SG11202009193VA - Full flow-through process for purifying recombinant proteins - Google Patents

Full flow-through process for purifying recombinant proteins

Info

Publication number
SG11202009193VA
SG11202009193VA SG11202009193VA SG11202009193VA SG11202009193VA SG 11202009193V A SG11202009193V A SG 11202009193VA SG 11202009193V A SG11202009193V A SG 11202009193VA SG 11202009193V A SG11202009193V A SG 11202009193VA SG 11202009193V A SG11202009193V A SG 11202009193VA
Authority
SG
Singapore
Prior art keywords
recombinant proteins
full flow
purifying recombinant
purifying
full
Prior art date
Application number
SG11202009193VA
Inventor
Didier Duthe
Céline Hemet
Benoit Mothes
Jérome Pezzini
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of SG11202009193VA publication Critical patent/SG11202009193VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/165Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
SG11202009193VA 2018-03-27 2019-03-27 Full flow-through process for purifying recombinant proteins SG11202009193VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18305338.8A EP3546475A1 (en) 2018-03-27 2018-03-27 Full flow-through process for purifying recombinant proteins
PCT/EP2019/057687 WO2019185691A1 (en) 2018-03-27 2019-03-27 Full flow-through process for purifying recombinant proteins

Publications (1)

Publication Number Publication Date
SG11202009193VA true SG11202009193VA (en) 2020-10-29

Family

ID=61972052

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202009193VA SG11202009193VA (en) 2018-03-27 2019-03-27 Full flow-through process for purifying recombinant proteins

Country Status (13)

Country Link
US (1) US20210009634A1 (en)
EP (2) EP3546475A1 (en)
JP (1) JP7396997B2 (en)
KR (1) KR20200135371A (en)
CN (1) CN112189015A (en)
AU (1) AU2019246328A1 (en)
BR (1) BR112020019409A2 (en)
CA (1) CA3095078A1 (en)
IL (1) IL277544A (en)
MX (1) MX2020010077A (en)
SG (1) SG11202009193VA (en)
TW (1) TWI828671B (en)
WO (1) WO2019185691A1 (en)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2001898A1 (en) * 2006-03-20 2008-12-17 Medarex Inc. Protein purification
MX2011001506A (en) * 2008-08-14 2011-03-15 Genentech Inc Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography.
SG189872A1 (en) * 2010-10-11 2013-06-28 Abbvie Inc Processes for purification of proteins
US20120238730A1 (en) * 2011-03-15 2012-09-20 Abbott Laboratories Integrated approach to the isolation and purification of antibodies
MX2013010737A (en) * 2011-03-25 2014-03-12 Genentech Inc Novel protein purification methods.
US9096648B2 (en) 2011-08-19 2015-08-04 Emd Millipore Corporation Methods of reducing level of one or more impurities in a sample during protein purification
WO2013075740A1 (en) * 2011-11-23 2013-05-30 Sanofi Antibody purification method
KR20200008022A (en) * 2011-12-22 2020-01-22 제넨테크, 인크. Ion exchange membrane chromatography
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
EP2864346B1 (en) * 2012-06-21 2018-10-17 Synthon Biopharmaceuticals B.V. Method of purifying an antibody
EP2682168A1 (en) * 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
US9650411B2 (en) * 2012-08-07 2017-05-16 Kyowa Hakko Kirin Co., Ltd. Method of purifying protein
MX2015012114A (en) 2013-03-08 2016-01-12 Genzyme Corp Continuous purification of therapeutic proteins.
DK3301115T3 (en) * 2013-05-06 2022-01-31 Sanofi Sa CONTINUOUS MULTI-STEP PROCEDURE FOR PURIFICATION OF ANTIBODIES
KR101569783B1 (en) * 2013-06-05 2015-11-19 한화케미칼 주식회사 A Method of Antibody Purification
EP3348565A1 (en) * 2014-02-19 2018-07-18 Agency For Science, Technology And Research Fractionation method
JP2017025025A (en) 2015-07-23 2017-02-02 旭化成メディカル株式会社 Protein purification method
JP7032046B2 (en) * 2016-01-22 2022-03-08 旭化成メディカル株式会社 Continuous constant flow rate purification method for bioactive substances
WO2018170488A1 (en) * 2017-03-17 2018-09-20 Gilead Sciences, Inc. Method of purifying an antibody

Also Published As

Publication number Publication date
TW201945385A (en) 2019-12-01
CA3095078A1 (en) 2019-10-03
RU2020131568A (en) 2022-04-27
US20210009634A1 (en) 2021-01-14
WO2019185691A1 (en) 2019-10-03
JP2021519303A (en) 2021-08-10
TWI828671B (en) 2024-01-11
EP3774839A1 (en) 2021-02-17
AU2019246328A1 (en) 2020-10-15
BR112020019409A2 (en) 2021-01-05
KR20200135371A (en) 2020-12-02
CN112189015A (en) 2021-01-05
JP7396997B2 (en) 2023-12-12
MX2020010077A (en) 2020-10-28
EP3546475A1 (en) 2019-10-02
IL277544A (en) 2020-11-30

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