SG11202109901TA - Protein binders for irhom2 - Google Patents
Protein binders for irhom2Info
- Publication number
- SG11202109901TA SG11202109901TA SG11202109901TA SG11202109901TA SG 11202109901T A SG11202109901T A SG 11202109901TA SG 11202109901T A SG11202109901T A SG 11202109901TA SG 11202109901T A SG11202109901T A SG 11202109901TA
- Authority
- SG
- Singapore
- Prior art keywords
- irhom2
- protein binders
- binders
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19168218 | 2019-04-09 | ||
| EP19209426 | 2019-11-15 | ||
| PCT/EP2020/060179 WO2020208150A1 (en) | 2019-04-09 | 2020-04-09 | Protein binders for irhom2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202109901TA true SG11202109901TA (en) | 2021-10-28 |
Family
ID=70166043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202109901T SG11202109901TA (en) | 2019-04-09 | 2020-04-09 | Protein binders for irhom2 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220204610A1 (en) |
| EP (1) | EP3952898A1 (en) |
| JP (2) | JP7285957B2 (en) |
| CN (1) | CN113993534A (en) |
| AU (2) | AU2020271402A1 (en) |
| CA (1) | CA3133163A1 (en) |
| SG (1) | SG11202109901TA (en) |
| WO (1) | WO2020208150A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024510415A (en) * | 2021-03-01 | 2024-03-07 | スキロム ゲゼルシャフト ミット ベシュレンクテル ハフツング | Humanized antibody against iRhom2 |
| CA3213771A1 (en) * | 2021-03-29 | 2022-10-06 | Scirhom Gmbh | Methods of treatment using protein binders to irhom2 epitopes |
| WO2023056365A2 (en) * | 2021-09-30 | 2023-04-06 | New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery | Irhom2 inhibitors and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US6548640B1 (en) | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| EP0368684B2 (en) | 1988-11-11 | 2004-09-29 | Medical Research Council | Cloning immunoglobulin variable domain sequences. |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| ES2176484T3 (en) | 1995-08-18 | 2002-12-01 | Morphosys Ag | PROTEIN BANKS / (POLI) PEPTIDES. |
| DE60301953T2 (en) | 2002-03-05 | 2006-07-27 | Artemis Pharmaceuticals Gmbh | MICE DERIVED FROM INNOVATION MALE DERIVED FROM EMBRYONIC STEM CELLS |
| US20150241429A1 (en) | 2012-09-11 | 2015-08-27 | Hospital For Special Surgery | Irhom2 inhibition for the treatment of complement mediated disorders |
| WO2014100602A1 (en) * | 2012-12-20 | 2014-06-26 | Hospital For Special Surgery | Treatment of egf-receptor dependent pathologies |
| US20170241986A1 (en) * | 2014-05-09 | 2017-08-24 | The Jackson Laboratory | Methods for identifying compounds that alter the activity of irhom polypeptides and use thereof |
-
2020
- 2020-04-09 SG SG11202109901T patent/SG11202109901TA/en unknown
- 2020-04-09 WO PCT/EP2020/060179 patent/WO2020208150A1/en active Search and Examination
- 2020-04-09 CN CN202080041229.3A patent/CN113993534A/en active Pending
- 2020-04-09 US US17/602,183 patent/US20220204610A1/en active Pending
- 2020-04-09 CA CA3133163A patent/CA3133163A1/en active Pending
- 2020-04-09 JP JP2021560639A patent/JP7285957B2/en active Active
- 2020-04-09 AU AU2020271402A patent/AU2020271402A1/en not_active Abandoned
- 2020-04-09 EP EP20716821.2A patent/EP3952898A1/en active Pending
-
2022
- 2022-10-11 AU AU2022252731A patent/AU2022252731A1/en active Pending
-
2023
- 2023-05-23 JP JP2023084229A patent/JP2023109906A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020208150A1 (en) | 2020-10-15 |
| JP7285957B2 (en) | 2023-06-02 |
| CN113993534A (en) | 2022-01-28 |
| JP2023109906A (en) | 2023-08-08 |
| EP3952898A1 (en) | 2022-02-16 |
| JP2022525239A (en) | 2022-05-11 |
| AU2020271402A1 (en) | 2021-10-07 |
| CA3133163A1 (en) | 2020-10-15 |
| US20220204610A1 (en) | 2022-06-30 |
| AU2022252731A1 (en) | 2022-11-10 |
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