SG11202007900XA - Process-scale synthesis of urolithin a - Google Patents

Process-scale synthesis of urolithin a

Info

Publication number
SG11202007900XA
SG11202007900XA SG11202007900XA SG11202007900XA SG11202007900XA SG 11202007900X A SG11202007900X A SG 11202007900XA SG 11202007900X A SG11202007900X A SG 11202007900XA SG 11202007900X A SG11202007900X A SG 11202007900XA SG 11202007900X A SG11202007900X A SG 11202007900XA
Authority
SG
Singapore
Prior art keywords
urolithin
scale synthesis
synthesis
scale
Prior art date
Application number
SG11202007900XA
Inventor
Wolfgang Skranc
George Yiannikouros
Alexander Trofimov
Zhixing Shan
Christopher Goss
Original Assignee
Amazentis Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amazentis Sa filed Critical Amazentis Sa
Publication of SG11202007900XA publication Critical patent/SG11202007900XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J27/00Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • B01J27/02Sulfur, selenium or tellurium; Compounds thereof
    • B01J27/053Sulfates
    • B01J27/055Sulfates with alkali metals, copper, gold or silver
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
SG11202007900XA 2018-02-27 2019-02-27 Process-scale synthesis of urolithin a SG11202007900XA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862635893P 2018-02-27 2018-02-27
US201862765125P 2018-08-17 2018-08-17
PCT/US2019/019817 WO2019168972A1 (en) 2018-02-27 2019-02-27 Process-scale synthesis of urolithin a

Publications (1)

Publication Number Publication Date
SG11202007900XA true SG11202007900XA (en) 2020-09-29

Family

ID=65763822

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202007900XA SG11202007900XA (en) 2018-02-27 2019-02-27 Process-scale synthesis of urolithin a

Country Status (13)

Country Link
US (3) US10906883B2 (en)
EP (1) EP3759087A1 (en)
JP (2) JP7449232B2 (en)
KR (1) KR20210053259A (en)
CN (1) CN112074510A (en)
AU (1) AU2019227733A1 (en)
BR (1) BR112020017449A2 (en)
CA (1) CA3092106A1 (en)
IL (1) IL276886A (en)
MX (1) MX2020008842A (en)
RU (1) RU2020128799A (en)
SG (1) SG11202007900XA (en)
WO (1) WO2019168972A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7449232B2 (en) 2018-02-27 2024-03-13 アマゼンティス エスアー Process scale synthesis of urolithin A
GB201912107D0 (en) 2019-08-22 2019-10-09 Amazentis Sa Combination
JP2024503753A (en) 2021-01-27 2024-01-26 ヴァンドリア エスアー Urolithin derivatives and their usage
WO2023161453A1 (en) 2022-02-24 2023-08-31 Amazentis Sa Uses of urolithins
US20230301890A1 (en) 2022-03-22 2023-09-28 Amazentis Sa Compositions comprising urolithins
CN115747098B (en) * 2022-10-09 2024-04-02 江苏海洋大学 Streptococcus thermophilus FUA329 and method for producing urolithin A by fermentation of streptococcus thermophilus FUA329

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5610883B2 (en) 1973-12-27 1981-03-11
US4496590A (en) 1983-04-18 1985-01-29 Sterling Drug Inc. Benzyl alcohol derivatives, their preparation and use
US5519133A (en) 1995-06-02 1996-05-21 American Cyanamid Co. 3-(3-aryloxyphenyl)-1-(substituted methyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal agents
US20050282781A1 (en) 2004-06-18 2005-12-22 Shibnath Ghosal Compositions of stable bioactive metabolites of docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids
US8894993B2 (en) 2006-08-04 2014-11-25 Natreon Inc. Mitochondria-targeted antioxidants
DE102008039083A1 (en) 2008-08-21 2010-02-25 Bayer Schering Pharma Aktiengesellschaft Substituted 5-aminopyrazoles and their use
JP5385686B2 (en) * 2009-06-05 2014-01-08 サントリーホールディングス株式会社 Platelet aggregation inhibitor
TW201309663A (en) * 2011-02-09 2013-03-01 參天製藥股份有限公司 3-hydroxy-6H-benzo-(c) chromene-6-one derivative and producing method thereof
KR20140028016A (en) 2011-04-22 2014-03-07 알러간, 인코포레이티드 Fatty acid amide hydrolase inhihibitors for treating
US9394269B2 (en) * 2013-12-23 2016-07-19 Amazentis Sa Process-scale synthesis of urolithins
EP3412274B1 (en) * 2016-02-02 2023-11-08 Daicel Corporation Urolithins-containing aqueous solution, dried solid composition thereof and production method therefor, and urolithins stabilizing method
EP3354645A1 (en) 2017-01-26 2018-08-01 Patheon Austria GmbH & Co KG Process for preparing urolithins
JP7449232B2 (en) 2018-02-27 2024-03-13 アマゼンティス エスアー Process scale synthesis of urolithin A

Also Published As

Publication number Publication date
EP3759087A1 (en) 2021-01-06
US10906883B2 (en) 2021-02-02
RU2020128799A (en) 2022-03-28
JP7449232B2 (en) 2024-03-13
WO2019168972A1 (en) 2019-09-06
US20230357176A1 (en) 2023-11-09
JP2021513994A (en) 2021-06-03
US20190263772A1 (en) 2019-08-29
BR112020017449A2 (en) 2020-12-22
RU2020128799A3 (en) 2022-03-28
CA3092106A1 (en) 2019-09-06
JP2024063152A (en) 2024-05-10
US11634401B2 (en) 2023-04-25
CN112074510A (en) 2020-12-11
AU2019227733A1 (en) 2020-09-24
MX2020008842A (en) 2020-10-05
KR20210053259A (en) 2021-05-11
IL276886A (en) 2020-10-29
US20210198225A1 (en) 2021-07-01

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