SG11202006422PA - Methods of treating cancers with antagonistic anti-pd-1 antibodies - Google Patents
Methods of treating cancers with antagonistic anti-pd-1 antibodiesInfo
- Publication number
- SG11202006422PA SG11202006422PA SG11202006422PA SG11202006422PA SG11202006422PA SG 11202006422P A SG11202006422P A SG 11202006422PA SG 11202006422P A SG11202006422P A SG 11202006422PA SG 11202006422P A SG11202006422P A SG 11202006422PA SG 11202006422P A SG11202006422P A SG 11202006422PA
- Authority
- SG
- Singapore
- Prior art keywords
- antibodies
- methods
- treating cancers
- antagonistic anti
- antagonistic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862620106P | 2018-01-22 | 2018-01-22 | |
| US201962794195P | 2019-01-18 | 2019-01-18 | |
| PCT/IB2019/050449 WO2019142149A2 (en) | 2018-01-22 | 2019-01-19 | Methods of treating cancers with antagonistic anti-pd-1 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202006422PA true SG11202006422PA (en) | 2020-08-28 |
Family
ID=65529735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202006422PA SG11202006422PA (en) | 2018-01-22 | 2019-01-19 | Methods of treating cancers with antagonistic anti-pd-1 antibodies |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20190225689A1 (zh) |
| EP (1) | EP3743159A2 (zh) |
| JP (1) | JP2021511341A (zh) |
| KR (1) | KR20200112867A (zh) |
| CN (1) | CN111629788A (zh) |
| AU (1) | AU2019208537A1 (zh) |
| BR (1) | BR112020014618A2 (zh) |
| CA (1) | CA3089174A1 (zh) |
| IL (1) | IL275897A (zh) |
| JO (1) | JOP20200177A1 (zh) |
| MA (1) | MA51677A (zh) |
| MX (1) | MX2020007748A (zh) |
| PH (1) | PH12020500576A1 (zh) |
| SG (1) | SG11202006422PA (zh) |
| WO (1) | WO2019142149A2 (zh) |
| ZA (1) | ZA202005223B (zh) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021123202A1 (en) | 2019-12-20 | 2021-06-24 | Formycon Ag | Formulations of anti-pd1 antibodies |
| TW202140012A (zh) | 2020-02-12 | 2021-11-01 | 比利時商健生藥品公司 | 用於治療尿路上皮癌的ｆｇｆｒ酪胺酸激酶抑制劑和抗ｐｄ１藥劑 |
| IL297963A (en) | 2020-05-07 | 2023-01-01 | Adorx Therapeutics Ltd | Adenosine a2a receptor antagonists |
| GB202011996D0 (en) | 2020-07-31 | 2020-09-16 | Adorx Therapeutics Ltd | Antagonist compounds |
| CN112194723B (zh) * | 2020-09-25 | 2021-09-21 | 广州百吉生物制药有限公司 | 一种免疫细胞在治疗癌症中应用 |
| GB202019622D0 (en) | 2020-12-11 | 2021-01-27 | Adorx Therapeutics Ltd | Antagonist compounds |
| CN115466328A (zh) * | 2021-06-11 | 2022-12-13 | 广东菲鹏制药股份有限公司 | 抗pd-1人源化抗体或其抗原结合片段及其应用 |
| KR20240024941A (ko) | 2021-06-23 | 2024-02-26 | 포르미콘 아게 | 항-pd1 항체의 제제 |
| GB2615307A (en) | 2022-01-28 | 2023-08-09 | Adorx Therapeutics Ltd | Antagonist compounds |
| WO2024133625A1 (en) | 2022-12-21 | 2024-06-27 | Formycon Ag | Formulations of anti-pd1 antibodies |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| EP0281604B1 (en) | 1986-09-02 | 1993-03-31 | Enzon Labs Inc. | Single polypeptide chain binding molecules |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US6255458B1 (en) | 1990-08-29 | 2001-07-03 | Genpharm International | High affinity human antibodies and human antibodies against digoxin |
| CA2103059C (en) | 1991-06-14 | 2005-03-22 | Paul J. Carter | Method for making humanized antibodies |
| ATE199392T1 (de) | 1992-12-04 | 2001-03-15 | Medical Res Council | Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung |
| AUPO591797A0 (en) | 1997-03-27 | 1997-04-24 | Commonwealth Scientific And Industrial Research Organisation | High avidity polyvalent and polyspecific reagents |
| US6818749B1 (en) | 1998-10-31 | 2004-11-16 | The United States Of America As Represented By The Department Of Health And Human Services | Variants of humanized anti carcinoma monoclonal antibody cc49 |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US7041870B2 (en) | 2000-11-30 | 2006-05-09 | Medarex, Inc. | Transgenic transchromosomal rodents for making human antibodies |
| EP2298809A3 (en) | 2001-07-12 | 2012-02-15 | FOOTE, Jefferson | Super humanized antibodies |
| JP2009526856A (ja) * | 2006-02-15 | 2009-07-23 | イムクローン・リミテッド・ライアビリティ・カンパニー | 抗体製剤 |
| US8748356B2 (en) | 2007-10-19 | 2014-06-10 | Janssen Biotech, Inc. | Methods for use in human-adapting monoclonal antibodies |
| JP2011507519A (ja) | 2007-12-19 | 2011-03-10 | セントコア・オーソ・バイオテツク・インコーポレーテツド | ｐＩＸ又はｐＶＩＩへの融合を介したヒトデノボｐＩＸファージディスプレイライブラリの設計及び作製、ベクター、抗体、及び方法 |
| EP2347038A4 (en) | 2008-10-14 | 2013-06-12 | Janssen Biotech Inc | METHOD FOR HUMANIZATION AND AFFINITY TREATMENT OF ANTIBODIES |
| NZ627859A (en) * | 2012-01-23 | 2015-09-25 | Regeneron Pharma | Stabilized formulations containing anti-ang2 antibodies |
| WO2014031718A1 (en) * | 2012-08-23 | 2014-02-27 | Merck Sharp & Dohme Corp. | Stable formulations of antibodies to tslp |
| US10392438B2 (en) * | 2014-05-16 | 2019-08-27 | Pfizer Inc. | Bispecific antibodies |
| US20180155429A1 (en) * | 2015-05-28 | 2018-06-07 | Bristol-Myers Squibb Company | Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody |
| EA201890578A1 (ru) * | 2015-09-24 | 2018-12-28 | Тева Фармасьютикалз Интернэшнл Гмбх | Предотвращение, лечение и снижение (персистирующей) посттравматической головной боли |
| WO2017055966A1 (en) * | 2015-10-01 | 2017-04-06 | Pfizer Inc. | Low viscosity antibody compositions |
| KR20180069070A (ko) * | 2015-11-03 | 2018-06-22 | 얀센 바이오테크 인코포레이티드 | Tim-3과 특이적으로 결합하는 항체 및 그의 용도 |
| CN108473569B (zh) * | 2016-01-11 | 2022-11-22 | 苏黎世大学 | 针对人白介素-2的免疫刺激性人源化单克隆抗体及其融合蛋白 |
| KR102515509B1 (ko) * | 2016-06-03 | 2023-03-28 | 브리스톨-마이어스 스큅 컴퍼니 | 결장직장암을 갖는 환자의 치료에서의 항-pd-1 항체의 용도 |
| US20210085663A1 (en) | 2017-05-16 | 2021-03-25 | Biomed Valley Discoveries, Inc. | Compositions and methods for treating cancer with atypical braf mutations |
-
2019
- 2019-01-18 US US16/252,295 patent/US20190225689A1/en active Pending
- 2019-01-19 SG SG11202006422PA patent/SG11202006422PA/en unknown
- 2019-01-19 EP EP19707451.1A patent/EP3743159A2/en active Pending
- 2019-01-19 JO JOP/2020/0177A patent/JOP20200177A1/ar unknown
- 2019-01-19 CN CN201980009617.0A patent/CN111629788A/zh active Pending
- 2019-01-19 WO PCT/IB2019/050449 patent/WO2019142149A2/en active Application Filing
- 2019-01-19 AU AU2019208537A patent/AU2019208537A1/en active Pending
- 2019-01-19 MA MA051677A patent/MA51677A/fr unknown
- 2019-01-19 BR BR112020014618-8A patent/BR112020014618A2/pt unknown
- 2019-01-19 CA CA3089174A patent/CA3089174A1/en active Pending
- 2019-01-19 MX MX2020007748A patent/MX2020007748A/es unknown
- 2019-01-19 JP JP2020540403A patent/JP2021511341A/ja active Pending
- 2019-01-19 KR KR1020207022367A patent/KR20200112867A/ko unknown
-
2020
- 2020-07-02 PH PH12020500576A patent/PH12020500576A1/en unknown
- 2020-07-07 IL IL275897A patent/IL275897A/en unknown
- 2020-08-21 ZA ZA2020/05223A patent/ZA202005223B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021511341A (ja) | 2021-05-06 |
| MX2020007748A (es) | 2020-09-25 |
| EP3743159A2 (en) | 2020-12-02 |
| US20190225689A1 (en) | 2019-07-25 |
| JOP20200177A1 (ar) | 2020-07-19 |
| KR20200112867A (ko) | 2020-10-05 |
| IL275897A (en) | 2020-08-31 |
| WO2019142149A3 (en) | 2019-09-26 |
| MA51677A (fr) | 2020-12-02 |
| CA3089174A1 (en) | 2019-07-25 |
| PH12020500576A1 (en) | 2021-05-17 |
| CN111629788A (zh) | 2020-09-04 |
| AU2019208537A1 (en) | 2020-07-09 |
| WO2019142149A2 (en) | 2019-07-25 |
| ZA202005223B (en) | 2022-03-30 |
| BR112020014618A2 (pt) | 2020-12-08 |
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