SG11202005360TA - Glycosidic derivatives of treprostinil - Google Patents
Glycosidic derivatives of treprostinilInfo
- Publication number
- SG11202005360TA SG11202005360TA SG11202005360TA SG11202005360TA SG11202005360TA SG 11202005360T A SG11202005360T A SG 11202005360TA SG 11202005360T A SG11202005360T A SG 11202005360TA SG 11202005360T A SG11202005360T A SG 11202005360TA SG 11202005360T A SG11202005360T A SG 11202005360TA
- Authority
- SG
- Singapore
- Prior art keywords
- treprostinil
- glycosidic derivatives
- glycosidic
- derivatives
- Prior art date
Links
- PAJMKGZZBBTTOY-ZFORQUDYSA-N treprostinil Chemical class C1=CC=C(OCC(O)=O)C2=C1C[C@@H]1[C@@H](CC[C@@H](O)CCCCC)[C@H](O)C[C@@H]1C2 PAJMKGZZBBTTOY-ZFORQUDYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17207329.8A EP3498283A1 (en) | 2017-12-14 | 2017-12-14 | Glycosidic derivatives of treprostinil |
| PCT/EP2018/084779 WO2019115702A1 (en) | 2017-12-14 | 2018-12-13 | Glycosidic derivatives of treprostinil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202005360TA true SG11202005360TA (en) | 2020-07-29 |
Family
ID=60673569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202005360TA SG11202005360TA (en) | 2017-12-14 | 2018-12-13 | Glycosidic derivatives of treprostinil |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US11427609B2 (he) |
| EP (2) | EP3498283A1 (he) |
| JP (1) | JP7295877B2 (he) |
| KR (1) | KR20200099134A (he) |
| CN (1) | CN111447933A (he) |
| AU (1) | AU2018382556B2 (he) |
| BR (1) | BR112020010945A2 (he) |
| CA (1) | CA3085398A1 (he) |
| CL (1) | CL2020001559A1 (he) |
| IL (1) | IL275127B2 (he) |
| MX (1) | MX2020006173A (he) |
| RU (1) | RU2020119175A (he) |
| SG (1) | SG11202005360TA (he) |
| WO (1) | WO2019115702A1 (he) |
| ZA (1) | ZA202002725B (he) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023529828A (ja) | 2020-06-09 | 2023-07-12 | ユナイテッド セラピューティクス コーポレイション | トレプロスチニルのフマリルジケトピペリジンプロドラッグ |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8814438D0 (en) | 1988-06-17 | 1988-07-20 | Wellcome Found | Compounds for use in medicine |
| US6521212B1 (en) | 1999-03-18 | 2003-02-18 | United Therapeutics Corporation | Method for treating peripheral vascular disease by administering benzindene prostaglandins by inhalation |
| CA2359652A1 (en) | 1999-03-31 | 2000-10-05 | United Therapeutics Corporation | Novel prostaglandin compounds and derivatives thereof, compositions containing the same and method of using the same for the treatment of peripheral vascular disease and pulmonaryhypertension |
| US20030108512A1 (en) | 2001-12-10 | 2003-06-12 | Robert Shorr | Modified prostaglandin compounds and analogs thereof, compositions containing the same useful for the treatment of cancer |
| CN102697790A (zh) * | 2003-05-22 | 2012-10-03 | 联合治疗公司 | 化合物和释放前列环素类似物的方法 |
| FI3851447T3 (fi) | 2006-10-12 | 2023-11-15 | Bellus Health Inc | Menetelmiä, yhdisteitä, koostumuksia ja vehikkeleitä 3-amino-1-propaanisulfonihapon vapauttamiseksi |
| EA029760B1 (ru) | 2011-02-07 | 2018-05-31 | Сифарм Сарл | ПРИМЕНЕНИЕ КОМПОЗИЦИИ ПРОСТАЦИКЛИНА И ИНГИБИТОРА ФОСФОДИЭСТЕРАЗЫ 4 ИЛИ ИХ АНАЛОГОВ ДЛЯ ЛЕЧЕНИЯ МУКОВИСЦИДОЗА И УВЕЛИЧЕНИЯ цАМФ В ЭПИТЕЛИАЛЬНЫХ КЛЕТКАХ |
| AU2012296954B2 (en) | 2011-08-12 | 2016-09-15 | Ascendis Pharma A/S | Carrier-linked treprostinil prodrugs |
| PL2674413T3 (pl) | 2012-06-15 | 2018-05-30 | Scipharm Sàrl | Sposób wytwarzania treprostynilu i jego pochodnych |
| CA2893604A1 (en) | 2012-12-07 | 2014-06-12 | Cayman Chemical Company Incorporated | Methods of synthesizing a prostacyclin analog |
| ES2927844T3 (es) | 2013-01-11 | 2022-11-11 | Corsair Pharma Inc | Profármacos de treprostinil |
| US9505737B2 (en) * | 2013-01-11 | 2016-11-29 | Corsair Pharma, Inc. | Treprostinil derivative compounds and methods of using same |
| EP3250289A1 (en) | 2015-01-27 | 2017-12-06 | SciPharm SàRL | Composition for the treatment of hepatic veno-occlusive disease |
| US9643911B2 (en) * | 2015-06-17 | 2017-05-09 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
| US9394227B1 (en) * | 2015-06-17 | 2016-07-19 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
-
2017
- 2017-12-14 EP EP17207329.8A patent/EP3498283A1/en not_active Withdrawn
-
2018
- 2018-12-13 SG SG11202005360TA patent/SG11202005360TA/en unknown
- 2018-12-13 KR KR1020207015807A patent/KR20200099134A/ko active IP Right Grant
- 2018-12-13 JP JP2020552123A patent/JP7295877B2/ja active Active
- 2018-12-13 RU RU2020119175A patent/RU2020119175A/ru unknown
- 2018-12-13 CA CA3085398A patent/CA3085398A1/en active Pending
- 2018-12-13 CN CN201880079687.9A patent/CN111447933A/zh active Pending
- 2018-12-13 AU AU2018382556A patent/AU2018382556B2/en active Active
- 2018-12-13 IL IL275127A patent/IL275127B2/he unknown
- 2018-12-13 US US16/771,741 patent/US11427609B2/en active Active
- 2018-12-13 WO PCT/EP2018/084779 patent/WO2019115702A1/en active Application Filing
- 2018-12-13 EP EP18829270.0A patent/EP3723769A1/en active Pending
- 2018-12-13 MX MX2020006173A patent/MX2020006173A/es unknown
- 2018-12-13 BR BR112020010945-2A patent/BR112020010945A2/pt unknown
-
2020
- 2020-05-13 ZA ZA2020/02725A patent/ZA202002725B/en unknown
- 2020-06-11 CL CL2020001559A patent/CL2020001559A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3723769A1 (en) | 2020-10-21 |
| RU2020119175A (ru) | 2022-01-14 |
| IL275127A (he) | 2020-07-30 |
| IL275127B1 (he) | 2023-07-01 |
| AU2018382556A1 (en) | 2020-05-28 |
| KR20200099134A (ko) | 2020-08-21 |
| CL2020001559A1 (es) | 2021-03-12 |
| US20210087216A1 (en) | 2021-03-25 |
| CA3085398A1 (en) | 2019-06-20 |
| WO2019115702A1 (en) | 2019-06-20 |
| EP3498283A1 (en) | 2019-06-19 |
| IL275127B2 (he) | 2023-11-01 |
| JP2021506959A (ja) | 2021-02-22 |
| JP7295877B2 (ja) | 2023-06-21 |
| US11427609B2 (en) | 2022-08-30 |
| RU2020119175A3 (he) | 2022-01-14 |
| MX2020006173A (es) | 2020-10-12 |
| ZA202002725B (en) | 2021-08-25 |
| BR112020010945A2 (pt) | 2020-11-17 |
| CN111447933A (zh) | 2020-07-24 |
| AU2018382556B2 (en) | 2024-03-14 |
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