SG11202003888VA - Reagents and methods for elemental imaging mass spectrometry of biological samples - Google Patents

Reagents and methods for elemental imaging mass spectrometry of biological samples

Info

Publication number
SG11202003888VA
SG11202003888VA SG11202003888VA SG11202003888VA SG11202003888VA SG 11202003888V A SG11202003888V A SG 11202003888VA SG 11202003888V A SG11202003888V A SG 11202003888VA SG 11202003888V A SG11202003888V A SG 11202003888VA SG 11202003888V A SG11202003888V A SG 11202003888VA
Authority
SG
Singapore
Prior art keywords
reagents
methods
mass spectrometry
biological samples
imaging mass
Prior art date
Application number
SG11202003888VA
Other languages
English (en)
Inventor
Olga Ornatsky
Qing Chang
Bedilu Allo
Xudong Lou
Alexander Bouzekri
Original Assignee
Fluidigm Canada Inc
Qing Chang
Bedilu Allo
Xudong Lou
Alexander Bouzekri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fluidigm Canada Inc, Qing Chang, Bedilu Allo, Xudong Lou, Alexander Bouzekri filed Critical Fluidigm Canada Inc
Publication of SG11202003888VA publication Critical patent/SG11202003888VA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13Labelling of peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
SG11202003888VA 2017-11-03 2018-06-08 Reagents and methods for elemental imaging mass spectrometry of biological samples SG11202003888VA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762581584P 2017-11-03 2017-11-03
US201762582280P 2017-11-06 2017-11-06
US201862644903P 2018-03-19 2018-03-19
PCT/US2018/036622 WO2019089088A1 (fr) 2017-11-03 2018-06-08 Réactifs et procédés de spectrométrie de masse pour l'imagerie élémentaire d'échantillons biologiques

Publications (1)

Publication Number Publication Date
SG11202003888VA true SG11202003888VA (en) 2020-05-28

Family

ID=66333317

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003888VA SG11202003888VA (en) 2017-11-03 2018-06-08 Reagents and methods for elemental imaging mass spectrometry of biological samples

Country Status (5)

Country Link
US (1) US20210181186A1 (fr)
EP (1) EP3704133A4 (fr)
CA (1) CA3081543A1 (fr)
SG (1) SG11202003888VA (fr)
WO (1) WO2019089088A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020055810A1 (fr) * 2018-09-10 2020-03-19 Fluidigm Canada Inc. Appareil et procédé d'imagerie d'échantillon à mise au point automatique
EP3850334A4 (fr) * 2018-09-10 2022-06-01 Fluidigm Canada Inc. Normalisation basée sur des particules de référence fusionnées pour spectrométrie de masse d'imagerie
AU2020274563A1 (en) * 2019-05-13 2021-12-09 Shanghai Polaris Biology Co., Ltd. A tag for labeling biomolecules
CN115135680A (zh) * 2019-12-18 2022-09-30 标准生物工具加拿大公司 用于信号放大的质谱细胞术试剂和方法
US11796721B2 (en) * 2020-06-09 2023-10-24 IonQ, Inc. Parabolic Cassegrain-type reflector for ablation loading
CN114085485B (zh) * 2021-12-08 2022-12-13 四川大学 改性胶原纤维的制备及其在橡胶中的应用
CN116027023B (zh) * 2022-08-15 2023-11-14 汉王科技股份有限公司 金属纳米簇及其制备方法和检测嗅觉受体激活信号的方法
CN115452929B (zh) * 2022-09-30 2023-04-21 上海立迪生物技术股份有限公司 一种成像质谱流式的信号校准方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225326A (en) 1988-08-31 1993-07-06 Research Development Foundation One step in situ hybridization assay
US8114636B2 (en) * 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids
DK2444804T3 (en) * 2006-05-27 2015-11-30 Fluidigm Canada Inc Polymer Skeleton element labels
JP2010521142A (ja) 2007-03-16 2010-06-24 ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド 遺伝子発現アッセイ
WO2011038158A2 (fr) * 2009-09-23 2011-03-31 Life Technologies Corporation Procédés, compositions, systèmes et appareil pour la production d'une matrice moléculaire
GB201001088D0 (en) * 2010-01-23 2010-03-10 Trillion Genomics Ltd Detection
WO2011134474A1 (fr) 2010-04-30 2011-11-03 Exiqon A/S Procédé et tampon d'hybridation in situ
WO2013019794A1 (fr) * 2011-08-01 2013-02-07 The General Hospital Corporation Banques de protéines et de peptides
LT3701971T (lt) * 2014-03-14 2023-01-10 Biomolecular Holdings Llc Junginiai, naudingi hibridinio imunoglobulino, turinčio nepeptidilo ryšį, gamyboje
WO2016145416A2 (fr) * 2015-03-11 2016-09-15 The Broad Institute, Inc. Analyse protéomique avec des identificateurs d'acide nucléique
WO2017004203A1 (fr) * 2015-06-29 2017-01-05 Fluidigm Canada Inc. Systèmes, procédés et compositions pour la détection simultanée d'arn et de protéine par spectrométrie de masse

Also Published As

Publication number Publication date
EP3704133A1 (fr) 2020-09-09
CA3081543A1 (fr) 2019-05-09
EP3704133A4 (fr) 2021-08-04
WO2019089088A1 (fr) 2019-05-09
US20210181186A1 (en) 2021-06-17

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