SG11202003888VA - Reagents and methods for elemental imaging mass spectrometry of biological samples - Google Patents

Reagents and methods for elemental imaging mass spectrometry of biological samples

Info

Publication number
SG11202003888VA
SG11202003888VA SG11202003888VA SG11202003888VA SG11202003888VA SG 11202003888V A SG11202003888V A SG 11202003888VA SG 11202003888V A SG11202003888V A SG 11202003888VA SG 11202003888V A SG11202003888V A SG 11202003888VA SG 11202003888V A SG11202003888V A SG 11202003888VA
Authority
SG
Singapore
Prior art keywords
reagents
methods
mass spectrometry
biological samples
imaging mass
Prior art date
Application number
SG11202003888VA
Inventor
Olga Ornatsky
Qing Chang
Bedilu Allo
Xudong Lou
Alexander Bouzekri
Original Assignee
Fluidigm Canada Inc
Qing Chang
Bedilu Allo
Xudong Lou
Alexander Bouzekri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fluidigm Canada Inc, Qing Chang, Bedilu Allo, Xudong Lou, Alexander Bouzekri filed Critical Fluidigm Canada Inc
Publication of SG11202003888VA publication Critical patent/SG11202003888VA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13Labelling of peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
SG11202003888VA 2017-11-03 2018-06-08 Reagents and methods for elemental imaging mass spectrometry of biological samples SG11202003888VA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762581584P 2017-11-03 2017-11-03
US201762582280P 2017-11-06 2017-11-06
US201862644903P 2018-03-19 2018-03-19
PCT/US2018/036622 WO2019089088A1 (en) 2017-11-03 2018-06-08 Reagents and methods for elemental imaging mass spectrometry of biological samples

Publications (1)

Publication Number Publication Date
SG11202003888VA true SG11202003888VA (en) 2020-05-28

Family

ID=66333317

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003888VA SG11202003888VA (en) 2017-11-03 2018-06-08 Reagents and methods for elemental imaging mass spectrometry of biological samples

Country Status (5)

Country Link
US (1) US20210181186A1 (en)
EP (1) EP3704133A4 (en)
CA (1) CA3081543A1 (en)
SG (1) SG11202003888VA (en)
WO (1) WO2019089088A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113167691A (en) * 2018-09-10 2021-07-23 富鲁达加拿大公司 Autofocus sample imaging apparatus and method
EP3850334A4 (en) * 2018-09-10 2022-06-01 Fluidigm Canada Inc. Fused-reference particle based normalisation for imaging mass spectrometry
EP3970208A4 (en) * 2019-05-13 2023-07-26 Shanghai Polaris Biology Co., Ltd. A tag for labeling biomolecules
US20230236105A1 (en) * 2019-12-18 2023-07-27 Standard Biotools Canada Inc. Mass cytometry reagents and methods for signal amplification
US11796721B2 (en) * 2020-06-09 2023-10-24 IonQ, Inc. Parabolic Cassegrain-type reflector for ablation loading
CN114085485B (en) * 2021-12-08 2022-12-13 四川大学 Preparation of modified collagen fiber and application thereof in rubber
CN116027023B (en) * 2022-08-15 2023-11-14 汉王科技股份有限公司 Metal nanocluster, preparation method thereof and method for detecting olfactory receptor activation signal
CN116429870A (en) * 2022-09-30 2023-07-14 上海立迪生物技术股份有限公司 Method for eliminating imaging mass spectrum flow type sensitivity difference

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225326A (en) 1988-08-31 1993-07-06 Research Development Foundation One step in situ hybridization assay
US8114636B2 (en) * 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids
EP2444804B1 (en) * 2006-05-27 2015-10-07 Fluidigm Canada Inc. Polymer backbone element tags
US20100092972A1 (en) 2007-03-16 2010-04-15 Human Genetic Signatures Pty Ltd. Assay for gene expression
WO2011038158A2 (en) * 2009-09-23 2011-03-31 Life Technologies Corporation Methods, compositions, systems and apparatus for molecular array fabrication
GB201001088D0 (en) * 2010-01-23 2010-03-10 Trillion Genomics Ltd Detection
EP2563935B1 (en) 2010-04-30 2014-04-16 Exiqon A/S In situ hybridization method and buffer.
CA2843955A1 (en) * 2011-08-01 2013-02-07 The General Hospital Corporation Protein and peptide libraries
MX2016011934A (en) * 2014-03-14 2017-04-13 J Capon Daniel Hybrid immunoglobulin containing non-peptidyl linkage.
WO2016145416A2 (en) * 2015-03-11 2016-09-15 The Broad Institute, Inc. Proteomic analysis with nucleic acid identifiers
EP3325493A4 (en) 2015-06-29 2019-03-13 Fluidigm Canada Inc. Systems, methods and compositions for simultaneous detection of rna and protein by mass spectrometry

Also Published As

Publication number Publication date
CA3081543A1 (en) 2019-05-09
WO2019089088A1 (en) 2019-05-09
EP3704133A1 (en) 2020-09-09
US20210181186A1 (en) 2021-06-17
EP3704133A4 (en) 2021-08-04

Similar Documents

Publication Publication Date Title
SG11202003888VA (en) Reagents and methods for elemental imaging mass spectrometry of biological samples
ZA201700540B (en) Instrument for analyzing biological samples and reagents
ZA201901986B (en) Devices and methods for sample analysis
ZA201901985B (en) Devices and methods for sample analysis
GB201811292D0 (en) Instrument for analytical sample preparation
GB2556994B (en) Identification of bacterial strains in biological samples using mass spectrometry
IL253860B (en) Devices for biological sample collection and analysis and methods of use thereof
GB2557891B (en) Improved sample preparation apparatus and method for elemental analysis spectrometer
GB2544838B (en) Elemental analysis of organic samples
GB2590574B (en) Biological sample processing device
EP3784768A4 (en) Reagents and methods for elemental mass spectrometry of biological samples
EP3553528A4 (en) Biological sample analysis device
EP3654021A4 (en) Biological sample analysis device
GB201802581D0 (en) Analysis of food samples
EP3410096A4 (en) Biological sample imaging device and biological sample imaging method
GB201610425D0 (en) Analysis of images of biological material
GB201610426D0 (en) Sample holder for image based analysis of samples
GB201610434D0 (en) Image based analysis of samples
PL3476297T3 (en) Apparatus for the analysis of samples taken by biopsy
GB2558482B (en) Biological sample analyzer and biological sample analysis method
EP3630358A4 (en) Devices and methods for rapid sample processing and analysis
GB2584934B (en) Evaluation of complex mass spectrometry data from biological samples
IL279184A (en) Methods for fingerprinting of biological samples
GB2556225B (en) Sample mass spectrum analysis
HK1247045A1 (en) Handling of biological samples