SG11202002943PA - Method for production of recombinant erwinia asparaginase - Google Patents
Method for production of recombinant erwinia asparaginaseInfo
- Publication number
- SG11202002943PA SG11202002943PA SG11202002943PA SG11202002943PA SG11202002943PA SG 11202002943P A SG11202002943P A SG 11202002943PA SG 11202002943P A SG11202002943P A SG 11202002943PA SG 11202002943P A SG11202002943P A SG 11202002943PA SG 11202002943P A SG11202002943P A SG 11202002943PA
- Authority
- SG
- Singapore
- Prior art keywords
- production
- erwinia asparaginase
- recombinant erwinia
- recombinant
- asparaginase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/01001—Asparaginase (3.5.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C12N9/82—Asparaginase (3.5.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/38—Pseudomonas
- C12R2001/39—Pseudomonas fluorescens
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762578305P | 2017-10-27 | 2017-10-27 | |
| PCT/US2018/056374 WO2019083793A1 (fr) | 2017-10-27 | 2018-10-17 | Procédé de production d'erwinia asparaginase de recombinaison |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202002943PA true SG11202002943PA (en) | 2020-05-28 |
Family
ID=66242732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202002943PA SG11202002943PA (en) | 2017-10-27 | 2018-10-17 | Method for production of recombinant erwinia asparaginase |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10787671B2 (fr) |
| EP (1) | EP3700921A4 (fr) |
| JP (2) | JP2021500896A (fr) |
| CN (1) | CN111278852A (fr) |
| AU (1) | AU2018354067B2 (fr) |
| SG (1) | SG11202002943PA (fr) |
| WO (1) | WO2019083793A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7358347B2 (ja) * | 2017-10-27 | 2023-10-10 | フェネックス インク． | 組み換えＥ．ｃｏｌｉアスパラギナーゼの製造のための方法 |
| WO2019083793A1 (fr) * | 2017-10-27 | 2019-05-02 | Pfenex Inc. | Procédé de production d'erwinia asparaginase de recombinaison |
| EP3747461A1 (fr) * | 2019-06-04 | 2020-12-09 | Kyon Biotech AG | Thérapie du cancer basée sur de l'asparaginase |
| BR112022007677A2 (pt) * | 2019-10-25 | 2022-10-25 | Jazz Pharmaceuticals Ireland Ltd | L-asparaginase recombinante |
| CN112341533A (zh) * | 2020-11-20 | 2021-02-09 | 东北师范大学 | 无标签人半乳糖凝集素13及其制备方法和应用 |
| KR20230125179A (ko) | 2020-12-23 | 2023-08-29 | 재즈 파마슈티칼즈 아일랜드 리미티드 | 전하-차폐 융합 단백질의 정제 방법 |
| WO2022211829A1 (fr) | 2021-03-30 | 2022-10-06 | Jazz Pharmaceuticals Ireland Ltd. | Dosage de l-asparaginase recombinante |
| WO2024015529A2 (fr) | 2022-07-14 | 2024-01-18 | Jazz Pharmaceuticals Ireland Ltd. | Polythérapies impliquant la l-asparaginase |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4551433A (en) | 1981-05-18 | 1985-11-05 | Genentech, Inc. | Microbial hybrid promoters |
| US4755465A (en) | 1983-04-25 | 1988-07-05 | Genentech, Inc. | Secretion of correctly processed human growth hormone in E. coli and Pseudomonas |
| US5281532A (en) | 1983-07-27 | 1994-01-25 | Mycogen Corporation | Pseudomas hosts transformed with bacillus endotoxin genes |
| US4695462A (en) | 1985-06-28 | 1987-09-22 | Mycogen Corporation | Cellular encapsulation of biological pesticides |
| US4695455A (en) | 1985-01-22 | 1987-09-22 | Mycogen Corporation | Cellular encapsulation of pesticides produced by expression of heterologous genes |
| GB8517071D0 (en) | 1985-07-05 | 1985-08-14 | Hoffmann La Roche | Gram-positive expression control sequence |
| GB8519753D0 (en) * | 1985-08-06 | 1985-09-11 | Health Lab Service Board | Production of 1-asparaginase |
| US5128130A (en) | 1988-01-22 | 1992-07-07 | Mycogen Corporation | Hybrid Bacillus thuringiensis gene, plasmid and transformed Pseudomonas fluorescens |
| US5055294A (en) | 1988-03-03 | 1991-10-08 | Mycogen Corporation | Chimeric bacillus thuringiensis crystal protein gene comprising hd-73 and berliner 1715 toxin genes, transformed and expressed in pseudomonas fluorescens |
| US5169760A (en) | 1989-07-27 | 1992-12-08 | Mycogen Corporation | Method, vectors, and host cells for the control of expression of heterologous genes from lac operated promoters |
| GB9017002D0 (en) | 1990-08-02 | 1990-09-19 | Health Lab Service Board | Improved method for the purification of erwina l-asparaginase |
| US9453251B2 (en) * | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| CN1906294B (zh) | 2003-11-19 | 2013-09-11 | 陶氏环球技术公司 | 改良的蛋白表达系统 |
| EP2327718B1 (fr) | 2003-11-21 | 2016-03-23 | Pfenex, Inc. | Systèmes d'expression ameliorés à sécrétion du système SEC |
| CA2574953A1 (fr) * | 2004-07-26 | 2006-02-09 | Dow Global Technolgies Inc. | Procede permettant d'ameliorer l'expression d'une proteine par mise au point d'une souche par genie genetique |
| MX2008015213A (es) | 2006-05-30 | 2008-12-09 | Dow Global Technologies Inc | Metodo de optimizacion de codon. |
| WO2008011234A2 (fr) | 2006-06-30 | 2008-01-24 | Enzon Pharmaceuticals, Inc. | Hôte recombinant pour obtention de l-asparaginase ii |
| US7618799B2 (en) | 2007-01-31 | 2009-11-17 | Dow Global Technologies Inc | Bacterial leader sequences for increased expression |
| CA2682677A1 (fr) | 2007-04-20 | 2008-10-30 | Dsm Ip Assets B.V. | Nouvelles asparaginases et leurs utilisations |
| CN101688213A (zh) * | 2007-04-27 | 2010-03-31 | 陶氏环球技术公司 | 用于快速筛选微生物宿主以鉴定某些在表达异源蛋白质方面具有改善的产量和/或质量的菌株的方法 |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| WO2011003633A1 (fr) * | 2009-07-06 | 2011-01-13 | Alize Pharma Ii | L-asparaginase pegylée |
| ME02945B (fr) * | 2009-07-06 | 2018-04-20 | Jazz Pharmaceuticals Ii S A S | L-asparaginase pegylée |
| GB0917647D0 (en) | 2009-10-08 | 2009-11-25 | Glaxosmithkline Biolog Sa | Expression system |
| KR20130072201A (ko) | 2010-03-30 | 2013-07-01 | 피페넥스 인크. | 재조합 독소 단백질의 고수준 발현 |
| RU2441914C1 (ru) * | 2010-10-06 | 2012-02-10 | Учреждение Российской академии медицинских наук Научно-исследовательский институт биомедицинской химии имени В.Н. Ореховича РАМН (ИБМХ РАМН) | Способ получения субстанции рекомбинантной l-аспарагиназы erwinia carotovora |
| BR102014000585B1 (pt) | 2014-01-10 | 2021-01-12 | Coppe/Ufrj-Instituto Alberto Luiz Coimbra De Pós-Graduação | l-asparaginase recombinante de zymomonas |
| KR102092225B1 (ko) | 2014-04-30 | 2020-03-23 | 주식회사 엘지화학 | 고효율 분비능을 가지는 단백질 분비 인자 및 이를 포함하는 발현 벡터 |
| DK3227455T3 (da) * | 2014-12-01 | 2023-08-21 | Pfenex Inc | Fusionspartnere til peptidfremstilling |
| SG11202002989SA (en) | 2017-10-27 | 2020-05-28 | Pfenex Inc | Bacterial leader sequences for periplasmic protein expression |
| WO2019083793A1 (fr) | 2017-10-27 | 2019-05-02 | Pfenex Inc. | Procédé de production d'erwinia asparaginase de recombinaison |
| JP7358347B2 (ja) * | 2017-10-27 | 2023-10-10 | フェネックス インク． | 組み換えＥ．ｃｏｌｉアスパラギナーゼの製造のための方法 |
-
2018
- 2018-10-17 WO PCT/US2018/056374 patent/WO2019083793A1/fr unknown
- 2018-10-17 SG SG11202002943PA patent/SG11202002943PA/en unknown
- 2018-10-17 AU AU2018354067A patent/AU2018354067B2/en active Active
- 2018-10-17 CN CN201880069961.4A patent/CN111278852A/zh active Pending
- 2018-10-17 US US16/163,382 patent/US10787671B2/en active Active
- 2018-10-17 EP EP18870766.5A patent/EP3700921A4/fr active Pending
- 2018-10-17 JP JP2020523432A patent/JP2021500896A/ja active Pending
-
2020
- 2020-08-14 US US16/994,442 patent/US11377661B2/en active Active
-
2023
- 2023-06-06 JP JP2023093346A patent/JP2023123512A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3700921A1 (fr) | 2020-09-02 |
| US20210032640A1 (en) | 2021-02-04 |
| EP3700921A4 (fr) | 2021-12-15 |
| CN111278852A (zh) | 2020-06-12 |
| JP2021500896A (ja) | 2021-01-14 |
| US10787671B2 (en) | 2020-09-29 |
| WO2019083793A1 (fr) | 2019-05-02 |
| JP2023123512A (ja) | 2023-09-05 |
| AU2018354067B2 (en) | 2023-03-30 |
| AU2018354067A1 (en) | 2020-06-04 |
| US20190127742A1 (en) | 2019-05-02 |
| US11377661B2 (en) | 2022-07-05 |
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