SG11202002065VA - Preeclampsia biomarkers and related systems and methods - Google Patents
Preeclampsia biomarkers and related systems and methodsInfo
- Publication number
- SG11202002065VA SG11202002065VA SG11202002065VA SG11202002065VA SG11202002065VA SG 11202002065V A SG11202002065V A SG 11202002065VA SG 11202002065V A SG11202002065V A SG 11202002065VA SG 11202002065V A SG11202002065V A SG 11202002065VA SG 11202002065V A SG11202002065V A SG 11202002065VA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- related systems
- preeclampsia biomarkers
- preeclampsia
- biomarkers
- Prior art date
Links
- 239000000090 biomarker Substances 0.000 title 1
- 201000011461 pre-eclampsia Diseases 0.000 title 1
Classifications
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762558184P | 2017-09-13 | 2017-09-13 | |
PCT/US2018/050893 WO2019055661A1 (en) | 2017-09-13 | 2018-09-13 | Preeclampsia biomarkers and related systems and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202002065VA true SG11202002065VA (en) | 2020-04-29 |
Family
ID=65723874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202002065VA SG11202002065VA (en) | 2017-09-13 | 2018-09-13 | Preeclampsia biomarkers and related systems and methods |
Country Status (10)
Country | Link |
---|---|
US (3) | US20200264188A1 (en) |
EP (1) | EP3682250A4 (en) |
JP (1) | JP2020533595A (en) |
KR (1) | KR20200109293A (en) |
CN (1) | CN111094988A (en) |
AU (1) | AU2018331400A1 (en) |
CA (1) | CA3075688A1 (en) |
MX (1) | MX2020002788A (en) |
SG (1) | SG11202002065VA (en) |
WO (1) | WO2019055661A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019055661A1 (en) | 2017-09-13 | 2019-03-21 | Progenity, Inc. | Preeclampsia biomarkers and related systems and methods |
EP4070113A4 (en) | 2019-12-04 | 2023-12-20 | Biora Therapeutics, Inc. | Assessment of preeclampsia using assays for free and dissociated placental growth factor |
GB202012830D0 (en) * | 2020-08-17 | 2020-09-30 | Univ Tartu | Method of prognosing preeclampsia |
CN113724873B (en) * | 2021-08-31 | 2024-01-12 | 陕西佰美基因股份有限公司 | Preeclampsia risk prediction method based on MLP multi-platform calibration |
Family Cites Families (178)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4777964A (en) | 1986-01-02 | 1988-10-18 | David Briggs | System for obtaining blood samples and submitting for testing of aids |
US5223440A (en) | 1987-11-17 | 1993-06-29 | Adeza Biomedical Corporation | Ex vivo product of conception test to determine abortion |
US5096830A (en) | 1987-11-17 | 1992-03-17 | Adeza Biomedical Corporation | Preterm labor and membrane rupture test |
US5281522A (en) | 1988-09-15 | 1994-01-25 | Adeza Biomedical Corporation | Reagents and kits for determination of fetal fibronectin in a vaginal sample |
US4919889A (en) | 1988-09-15 | 1990-04-24 | Aspen Diagnostics Corporation | Sample collection and transport fluid composition |
JP3222135B2 (en) | 1991-11-04 | 2001-10-22 | アデザ バイオメディカル コーポレイション | Screening method to identify women at increased risk of preterm labor |
WO1993009432A1 (en) | 1991-11-04 | 1993-05-13 | Adeza Biomedical Corporation | Screening method for identifying women at increased risk for imminent delivery |
US5516702A (en) | 1991-11-06 | 1996-05-14 | Adeza Biomedical Corporation | Screening method for identifying women at increased risk for imminent delivery |
US5898005A (en) | 1993-02-24 | 1999-04-27 | Dade Behring Inc. | Rapid detection of analytes with receptors immobilized on soluble submicron particles |
ES2132392T3 (en) | 1993-02-24 | 1999-08-16 | Dade Behring Inc | IMMOBILIZATION OF SPECIFIC LINK TEST REAGENTS. |
US5783396A (en) | 1993-03-23 | 1998-07-21 | Voroteliak; Victor | Method of detecting rupture of the amniotic membranes in pregnant mammals |
US5431171A (en) | 1993-06-25 | 1995-07-11 | The Regents Of The University Of California | Monitoring fetal characteristics by radiotelemetric transmission |
ATE177842T1 (en) | 1993-09-03 | 1999-04-15 | Behringwerke Ag | FLUORESCENCE OXYGEN DUCTION IMMUNE TESTS |
US5650394A (en) | 1993-11-04 | 1997-07-22 | Adeza Biomedical | Use of urinastatin-like compounds to prevent premature delivery |
US5597700A (en) | 1994-04-28 | 1997-01-28 | California Research, Llc | Method for detecting free insulin-like growth-factor-binding protein 1 and a test device for detecting the ruptures of fetal membranes using the above method |
US6140099A (en) | 1994-05-20 | 2000-10-31 | The Trustees Of The University Of Pennsylvania | Method of delaying fetal membrane rupture by inhibiting matrix metalloproteinase-9 activity |
US5641636A (en) | 1994-05-20 | 1997-06-24 | University Of Pennsylvania | Method of predicting fetal membrane rupture based on matrix metalloproteinase-9 activity |
CA2211204C (en) | 1995-01-26 | 2003-10-07 | Merck Frosst Canada Inc. | Prostaglandin receptor dp |
EP0913405B1 (en) | 1995-10-31 | 2006-01-04 | Maruha Corporation | Monoclonal antibody specific for prostaglandin d synthetase |
US6678669B2 (en) | 1996-02-09 | 2004-01-13 | Adeza Biomedical Corporation | Method for selecting medical and biochemical diagnostic tests using neural network-related applications |
US6120460A (en) | 1996-09-04 | 2000-09-19 | Abreu; Marcio Marc | Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions |
US6544193B2 (en) | 1996-09-04 | 2003-04-08 | Marcio Marc Abreu | Noninvasive measurement of chemical substances |
FI963989A (en) | 1996-10-04 | 1998-04-05 | Wallac Oy | Homogeneous methods of determination based on the transmission of luminescence energy |
EP0968430A1 (en) | 1997-03-07 | 2000-01-05 | Mount Sinai Hospital Corporation | Methods to diagnose a required regulation of trophoblast invasion |
US6610480B1 (en) | 1997-11-10 | 2003-08-26 | Genentech, Inc. | Treatment and diagnosis of cardiac hypertrophy |
US6875567B1 (en) | 1997-11-10 | 2005-04-05 | Genentech, Inc. | Method of detecting cardiac hypertrophy through probe hybridization and gene expression analysis |
US20020031513A1 (en) | 1997-11-24 | 2002-03-14 | Shamir Leibovitz | Method and pharmaceutical composition for inhibiting premature rapture of fetal membranes, ripening of uterine cervix and preterm labor in mammals |
US6394952B1 (en) | 1998-02-03 | 2002-05-28 | Adeza Biomedical Corporation | Point of care diagnostic systems |
US6267722B1 (en) | 1998-02-03 | 2001-07-31 | Adeza Biomedical Corporation | Point of care diagnostic systems |
US6506789B2 (en) | 1998-06-03 | 2003-01-14 | Shionogi & Co., Ltd. | Methods for the treatment of itching comprising administering PGD2 receptor antagonist |
US6149590A (en) | 1998-07-22 | 2000-11-21 | Smith; Ramada S. | System for identifying premature rupture of membrane during pregnancy |
US6126597A (en) | 1998-07-22 | 2000-10-03 | Smith; Ramada S. | System for identifying premature rupture of membrane during pregnancy |
US20010025140A1 (en) | 1998-07-22 | 2001-09-27 | Torok Brian A. | System for identifying premature rupture of membrane during pregnancy |
US7109044B1 (en) | 1998-09-04 | 2006-09-19 | Maruha Corporation | Method of detection and disease state management for renal diseases |
KR20010089381A (en) | 1998-10-29 | 2001-10-06 | 파라비 레이 | Use of thiazolidinediones derivatives for preventing uterine contractions in premature labour or lactation |
JP2000249709A (en) | 1999-02-26 | 2000-09-14 | Maruha Corp | Predicting method for restenosis after coronary blood vessel intervention execution |
US6126616A (en) | 1999-06-21 | 2000-10-03 | Sanyal; Mrinal K. | Collection of biological products from human accessory reproductive organs by absorbent systems |
ATE315230T1 (en) | 1999-08-23 | 2006-02-15 | Bml Inc | METHOD FOR IDENTIFYING PROSTAGLANDIN D2 RECEPTOR MODULATORS |
FR2809182B1 (en) | 2000-05-18 | 2003-08-15 | Univ Rene Descartes | DETECTION OF IL-6 FOR PREDICTING PREMATURE DELIVERY RISKS |
US20010053876A1 (en) | 2000-06-15 | 2001-12-20 | Torok Brian A. | System for identifying premature rupture of membrane during pregnancy |
US6878522B2 (en) | 2000-07-07 | 2005-04-12 | Baiyong Li | Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2 |
CA2417669C (en) | 2000-07-21 | 2009-09-15 | Maruha Corporation | Methods for differentiating demential diseases |
US6410583B1 (en) | 2000-07-25 | 2002-06-25 | Merck Frosst Canada & Co. | Cyclopentanoindoles, compositions containing such compounds and methods of treatment |
WO2002017770A2 (en) | 2000-08-28 | 2002-03-07 | Morand Patrick G | Use of blood and plasma donor samples and data in the drug discovery process |
US7217725B2 (en) | 2000-09-14 | 2007-05-15 | Allergan, Inc. | Prostaglandin D2 antagonist |
EP1351985A2 (en) | 2000-10-16 | 2003-10-15 | Bayer Aktiengesellschaft | Polynucleotide and polypeptide sequences of human dendritic cell immunoreceptors |
US7635571B2 (en) | 2000-12-07 | 2009-12-22 | Siemens Healthcare Diagnostics Products Gmbh | Amplified signal in binding assays |
AU2002302248B2 (en) | 2001-05-23 | 2008-03-06 | Merck Frosst Canada Ltd. | Dihydropyrrolo[1,2-A]indole and tetrahydropyrido[1,2-A]-indole derivatives as prostaglandin D2 receptor antagonists |
WO2003008978A2 (en) | 2001-07-18 | 2003-01-30 | Merck Frosst Canada & Co. | Eosinophil prostaglandin d2 receptor assays |
US20040197834A1 (en) | 2001-07-20 | 2004-10-07 | Francois Gervais | Method to increase expression of pgd2 receptors and assays for identifying modulators of prostaglandin d2 receptors |
US20050101841A9 (en) | 2001-12-04 | 2005-05-12 | Kimberly-Clark Worldwide, Inc. | Healthcare networks with biosensors |
WO2004003555A1 (en) | 2002-07-01 | 2004-01-08 | University Of Rochester Medical Center | Method for determination of likelihood of occurrence of preterm labor in pregnant females |
DK2308507T3 (en) | 2002-07-19 | 2015-04-20 | Beth Israel Hospital | Methods for the treatment of preeclampsia |
US7435419B2 (en) | 2002-07-19 | 2008-10-14 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating pre-eclampsia or eclampsia |
ATE465410T1 (en) | 2002-08-13 | 2010-05-15 | N Dia Inc | DEVICES AND METHODS FOR DETECTING AMBIENT FLUID IN VAGINAL SECRETIONS |
DE60334462D1 (en) | 2002-08-29 | 2010-11-18 | Diagnostic Technologies Ltd | EN |
US20050215609A1 (en) | 2002-09-30 | 2005-09-29 | Masaaki Yoshikawa | Novel uses of prostaglandin d2, prostaglandin d2 agonist and prostaglandin d2 antagonist |
AU2003284166A1 (en) | 2002-10-23 | 2004-05-13 | University Of Hawaii | Methods for diagnosing and treating pre-term labor |
US20040100376A1 (en) | 2002-11-26 | 2004-05-27 | Kimberly-Clark Worldwide, Inc. | Healthcare monitoring system |
AU2003290773A1 (en) | 2003-02-05 | 2004-09-06 | Ciphergen Biosystems, Inc. | Non-invasive assessment of intra-amniotic environment |
US20040266025A1 (en) | 2003-02-06 | 2004-12-30 | Durlin Hickok | Screening and treatment methods for prevention of preterm delivery |
US8068990B2 (en) | 2003-03-25 | 2011-11-29 | Hologic, Inc. | Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids |
US7191068B2 (en) | 2003-03-25 | 2007-03-13 | Proteogenix, Inc. | Proteomic analysis of biological fluids |
US8003765B2 (en) | 2003-04-09 | 2011-08-23 | Stony Brook Anaesthesiology, University Faculty Practice Corporation | Methods, antibodies and kits for detecting cerebrospinal fluid in a sample |
US20040203079A1 (en) | 2003-04-09 | 2004-10-14 | Research Foundation Of The State University Of New York | Methods and kits for detecting cerebrospinal fluid in a sample |
US20070003992A1 (en) | 2003-04-09 | 2007-01-04 | Pentyala Srinivas N | Methods and kits for detecting cerebrospinal fluid in a sample |
WO2004098389A2 (en) | 2003-05-02 | 2004-11-18 | Johns Hopkins University | Devices, systems and methods for bioimpendence measurement of cervical tissue and methods for diagnosis and treatment of human cervix |
WO2004103970A1 (en) | 2003-05-20 | 2004-12-02 | Merck Frosst Canada Ltd. | Fluoro-methanesulfonyl-substituted cycloalkanoindoles and their use as prostaglandin d2 antagonists |
WO2005007223A2 (en) | 2003-07-16 | 2005-01-27 | Sasha John | Programmable medical drug delivery systems and methods for delivery of multiple fluids and concentrations |
JP3897117B2 (en) | 2003-09-24 | 2007-03-22 | マルハ株式会社 | Method for determining and predicting the severity of pregnancy toxemia, and for evaluating fetal / placental function in pregnancy toxemia |
WO2005031360A1 (en) | 2003-09-26 | 2005-04-07 | Maruha Corporation | Method of detecting or discriminating articular rheumatism and method of determining stage of disease or degree of dysfunction |
US20050131287A1 (en) | 2003-12-16 | 2005-06-16 | Kimberly-Clark Worldwide, Inc. | Detection of premature rupture of the amniotic membrane |
CA2575675A1 (en) | 2004-07-30 | 2006-03-09 | Adeza Biomedical Corporation | Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin |
US20080254479A1 (en) | 2004-08-30 | 2008-10-16 | Cervimark, Llc | Methods and Kits For Predicting Risk For Preterm Labor |
US20080090759A1 (en) | 2004-08-30 | 2008-04-17 | Robert Kokenyesi | Methods and kits for predicting risk for preterm labor |
CA2581336C (en) | 2004-09-24 | 2022-10-04 | S. Ananth Karumanchi | Diagnosis of pregnancy-related hypertensive disorder by measurement of soluble endoglin |
GB0422057D0 (en) | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
GT200500284A (en) | 2004-10-15 | 2006-03-27 | Aventis Pharma Inc | PYRIMIDINS AS ANTAGONISTS OF PROSTAGLANDINA D2 RECEPTOR |
CN101163970A (en) | 2004-12-21 | 2008-04-16 | 耶鲁大学 | Diagnosis of preeclampsia |
US20060166242A1 (en) | 2005-01-06 | 2006-07-27 | Mount Sinai Hospital | Markers of pre-term labor |
DOP2006000016A (en) | 2005-01-26 | 2006-07-31 | Aventis Pharma Inc | 2-PHENYL-INDOLES AS ANTAGONISTS OF THE PROSTAGLANDIN RECEPTOR D2. |
GB0505048D0 (en) | 2005-03-11 | 2005-04-20 | Oxagen Ltd | Compounds with PGD antagonist activity |
JP2008537776A (en) * | 2005-03-24 | 2008-09-25 | ベス イスラエル デアコネス メディカル センター | Method of diagnosing fetal trisomy 13 or risk of fetal trisomy 13 during pregnancy |
EP1910555A2 (en) | 2005-07-13 | 2008-04-16 | ECI Biotech Inc. | Substrates, sensors, and methods for assessing conditions in females |
US7842692B2 (en) | 2005-07-22 | 2010-11-30 | Shionogi & Co., Ltd. | Azaindole derivative having PGD2 receptor antagonistic activity |
EP1937709A4 (en) | 2005-09-15 | 2011-06-08 | Swiss Asian Property Ltd | A marker for prolonged rupture of membranes |
GT200600457A (en) | 2005-10-13 | 2007-04-27 | Aventis Pharma Inc | DIHYDROGEN PHOSPHATE SALT AS ANTAGONIST OF PROSTAGLANDINA D2 RECEPTOR |
WO2007047372A2 (en) | 2005-10-14 | 2007-04-26 | The Board Of Trustees Of The University Of Illinois | Pharmacological treatments for sleep disorders (apnoe) with prostanoid receptor antagonists |
US20070111326A1 (en) | 2005-11-14 | 2007-05-17 | Abbott Laboratories | Diagnostic method for proteinaceous binding pairs, cardiovascular conditions and preeclampsia |
US20080009552A1 (en) | 2006-03-23 | 2008-01-10 | Craig Pennell | Markers of pre-term labor |
DOP2007000068A (en) | 2006-04-12 | 2007-10-31 | Sanofi Aventis Us Llc | AMINO-PYRIMIDINE COMPOUNDS 2,6-SUBSTITUTES-4-MONOSUSTITUTES AS ANTAGONISTS OF PROSTAGLANDINA D2 RECEIVER |
ES2618352T3 (en) | 2006-06-16 | 2017-06-21 | The Trustees Of The University Of Pennsylvania | Prostaglandin D2 receptor antagonists for the treatment of androgenetic alopecia |
DE602007010010D1 (en) | 2006-07-25 | 2010-12-02 | Sanofi Aventis | 2-PHENYLINDOLE AS ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTOR |
US8133859B2 (en) | 2006-09-27 | 2012-03-13 | The United States Of America As Represented By The Department Of Health And Human Services | SCGB3A2 as a growth factor and anti-apoptotic agent |
US8642034B2 (en) | 2006-10-03 | 2014-02-04 | Genzyme Corporation | Use of TGF-β antagonists to treat infants at risk of developing bronchopulmonary dysplasia |
WO2008073491A1 (en) | 2006-12-11 | 2008-06-19 | University Of Florida Research Foundation, Inc. | System and method for analyzing progress of labor and preterm labor |
CA2672373C (en) | 2006-12-19 | 2011-08-30 | Pfizer Products Inc. | Nicotinamide derivatives as inhibitors of h-pgds and their use for treating prostaglandin d2 mediated diseases |
WO2008079407A1 (en) | 2006-12-26 | 2008-07-03 | Brigham Young University | Serum proteomics system and associated methods |
JP2010519328A (en) | 2007-02-26 | 2010-06-03 | ファイザー・プロダクツ・インク | Nicotinamide derivatives as inhibitors of H-PGDS and their use for the treatment of diseases mediated by prostaglandin D2 |
US20090058072A1 (en) | 2007-08-30 | 2009-03-05 | Shirlee Ann Weber | Record sheets with integrated themes |
WO2009039476A1 (en) | 2007-09-20 | 2009-03-26 | Johns Hopkins University | Treatment and prevention of ischemic brain injury |
WO2009059259A2 (en) | 2007-10-31 | 2009-05-07 | Children's Hospital Medical Center | Detection of worsening renal disease in subjects with systemic lupus erythematosus |
US20110002866A1 (en) | 2007-10-31 | 2011-01-06 | Lubit Beverly W | Methods to prevent a hair-related side effect of treatment with a chemotherapeutic agent |
WO2009061681A2 (en) | 2007-11-06 | 2009-05-14 | Amira Pharmaceuticals, Inc | Antagonists of pgd2 receptors |
US20130177485A1 (en) | 2007-11-27 | 2013-07-11 | Momtec Life Ltd. Of Yazmot Haemek | Diagnostic device for identifying rupture of membrane during pregnancy |
US20110065139A1 (en) | 2007-11-27 | 2011-03-17 | Jacob Mullerad | diagnostic device for identifying rupture of membrane during pregnancy |
AU2008337342B2 (en) | 2007-12-14 | 2012-05-24 | Pulmagen Therapeutics (Asthma) Limited | Indoles and their therapeutic use |
BRPI0907253A2 (en) | 2008-01-07 | 2015-07-14 | Ortho Clinical Diagnostics Inc | Determination of sflt-1 complex: angiogenic factor |
JP2011509985A (en) | 2008-01-18 | 2011-03-31 | プルマジェン セラピューティクス (アズマ) リミテッド | Indole active against CRTH2 receptor |
ES2523220T3 (en) | 2008-01-25 | 2014-11-24 | Perkinelmer Health Sciences, Inc. | Methods to determine the risk of prenatal complications |
WO2009097584A1 (en) | 2008-01-30 | 2009-08-06 | Proteogenix, Inc. | Maternal serum biomarkers for detection of pre-eclampsia |
US20100017143A1 (en) | 2008-01-30 | 2010-01-21 | Proteogenix, Inc. | Gestational age dependent proteomic changes of human maternal serum for monitoring maternal and fetal health |
EP2245002A4 (en) | 2008-02-01 | 2011-08-17 | Amira Pharmaceuticals Inc | N,n-disubstituted aminoalkylbiphenyl antagonists of prostaglandin d2 receptors |
US8168678B2 (en) | 2008-02-01 | 2012-05-01 | Panmira Pharmaceuticals, Inc. | N,N-disubstituted aminoalkylbiphenyl antagonists of prostaglandin D2 receptors |
WO2009102893A2 (en) | 2008-02-14 | 2009-08-20 | Amira Pharmaceuticals, Inc. | CYCLIC DIARYL ETHER COMPOUNDS AS ANTAGONISTS OF PROSTAGLANDIN D2 receptors |
US8497381B2 (en) | 2008-02-25 | 2013-07-30 | Panmira Pharmaceuticals, Llc | Antagonists of prostaglandin D2 receptors |
WO2009145989A2 (en) | 2008-04-02 | 2009-12-03 | Amira Pharmaceuticals, Inc. | Aminoalkylphenyl antagonists of prostaglandin d2 receptors |
US20110112134A1 (en) | 2008-05-16 | 2011-05-12 | Amira Pharmaceuticals, Inc. | Tricyclic Antagonists of Prostaglandin D2 Receptors |
US20110166070A1 (en) | 2008-05-16 | 2011-07-07 | Stewart Dennis R | Method of preventing premature delivery |
WO2010008864A2 (en) | 2008-06-24 | 2010-01-21 | Amira Pharmaceuticals, Inc. | Cycloalkane[b]indole angtagonists of prostaglandin d2 receptors |
BRPI0913930A2 (en) | 2008-07-03 | 2015-10-20 | Amira Pharmaceuticals Inc | prostaglandin d2 receptor antagonists |
FR2934681B1 (en) | 2008-07-29 | 2011-09-30 | Bastien Karkouche | DEVICE FOR CAPTURING BIOLOGICAL PARTICLES AND USE. |
AU2009279809A1 (en) | 2008-08-04 | 2010-02-11 | Risk Assessment Labs, L.L.C. | Multiplexed diagnostic test for preterm labor |
KR101406433B1 (en) | 2008-09-22 | 2014-06-13 | 카이맨 케미칼 컴파니 인코포레이티드 | Multiheteroaryl compounds as inhibitors of h-pgds and their use for treating prostaglandin d2 mediated diseases |
GB2463788B (en) | 2008-09-29 | 2010-12-15 | Amira Pharmaceuticals Inc | Heteroaryl antagonists of prostaglandin D2 receptors |
US8378107B2 (en) | 2008-10-01 | 2013-02-19 | Panmira Pharmaceuticals, Llc | Heteroaryl antagonists of prostaglandin D2 receptors |
WO2010042652A2 (en) | 2008-10-08 | 2010-04-15 | Amira Pharmaceuticals, Inc. | Heteroalkyl biphenyl antagonists of prostaglandin d2 receptors |
GB2465062B (en) | 2008-11-06 | 2011-04-13 | Amira Pharmaceuticals Inc | Cycloalkane(B)azaindole antagonists of prostaglandin D2 receptors |
WO2010057118A2 (en) | 2008-11-17 | 2010-05-20 | Amira Pharmaceuticals, Inc. | Heterocyclic antagonists of prostaglandin d2 receptors |
US9180114B2 (en) | 2008-11-26 | 2015-11-10 | President And Fellows Of Harvard College | Neurodegenerative diseases and methods of modeling |
WO2010085820A2 (en) | 2009-01-26 | 2010-07-29 | Amira Pharmaceuticals, Inc. | Tricyclic compounds as antagonists of prostaglandin d2 receptors |
WO2010099211A2 (en) | 2009-02-27 | 2010-09-02 | University Of Utah Research Foundation | Compositions and methods for diagnosing and preventing spontaneous preterm birth |
GB0905964D0 (en) | 2009-04-06 | 2009-05-20 | King S College London | Marker |
JP2013501052A (en) | 2009-08-05 | 2013-01-10 | パンミラ ファーマシューティカルズ,エルエルシー. | DP2 antagonist and use thereof |
US20110090048A1 (en) | 2009-09-29 | 2011-04-21 | Li Conan K | Data Transmission Device with User Identification Capability |
CA2779270A1 (en) | 2009-10-29 | 2011-05-05 | The Trustees Of The University Of Pennsylvania | Method of predicting risk of preterm birth |
CN102300497B (en) | 2009-11-12 | 2015-06-03 | 塞维兰兹公司 | Devices and methods for cervix measurement |
CN102667486B (en) | 2009-11-25 | 2016-03-09 | 霍洛吉克股份有限公司 | The detection of IAI |
EP2510356B1 (en) | 2009-12-08 | 2018-10-31 | Cedars-Sinai Medical Center | Diagnostic method to identify women at risk for preterm delivery |
WO2011103473A2 (en) | 2010-02-18 | 2011-08-25 | The Johns Hopkins University | Preterm labor monitor |
RU2012143897A (en) | 2010-03-16 | 2014-04-27 | Авентис Фармасьютикалз Инк. | SUBSTITUTED PYRIMIDINES AS ANTAGONISTS OF PROSTAGLANDINE RECEPTORS D2 |
TW201204708A (en) | 2010-03-16 | 2012-02-01 | Aventis Pharma Inc | A substituted pyrimidine as a prostaglandin D2 receptor antagonist |
AR080703A1 (en) | 2010-03-22 | 2012-05-02 | Actelion Pharmaceuticals Ltd | DERIVATIVES OF 3- (HETEROARIL-AMINO) -1,2,3,4-TETRAHIDRO-9H-CARBAZOL, MODULATORS OF PROSTAGLANDINE D2 RECEPTORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEMSELVES AND USE OF THEM IN THE TREATMENT OF ALLERGIC OR IMMUNE DISORDERS AS ASTHMA. |
US20110237972A1 (en) | 2010-03-23 | 2011-09-29 | Robert Garfield | Noninvasive measurement of uterine emg propagation and power spectrum frequency to predict true preterm labor and delivery |
JP2013524251A (en) * | 2010-04-13 | 2013-06-17 | プロノタ エヌ.ヴェ. | Biomarkers for pregnancy-induced hypertension |
JP5959506B2 (en) * | 2010-05-14 | 2016-08-02 | ベス イスラエル デアコネス メディカル センター インコーポレイテッド | Extracorporeal devices and methods for treating pregnancy complications |
US20110312927A1 (en) | 2010-06-18 | 2011-12-22 | Satish Kumar Nachaegari | Progesterone Containing Oral Dosage Forms and Related Methods |
US20110312928A1 (en) | 2010-06-18 | 2011-12-22 | Lipocine Inc. | Progesterone Containing Oral Dosage Forms and Related Methods |
WO2011163554A2 (en) | 2010-06-25 | 2011-12-29 | Winthrop-University Hospital | Lipocalin-type prostaglandin d2 synthase as a biomarker for lung cancer progression and prognosis |
BR112013000254A2 (en) | 2010-07-05 | 2016-05-24 | Actelion Pharmaceuticals Ltd | 1-phenyl-substituted heterocyclic derivatives and their use as prostaglandin d2 receptor modulators |
WO2012024034A1 (en) | 2010-07-12 | 2012-02-23 | Therasyn Sensors, Inc. | A device and methods for in vivo monitoring of an individual |
US8765487B2 (en) | 2010-09-01 | 2014-07-01 | Clinical Innovations | Detection of amniotic fluid in vaginal secretions of pregnant women due to premature rupture of fetal membranes |
CN103201628B (en) | 2010-10-01 | 2015-09-16 | 霍罗杰克股份有限公司 | For the immunoassay test strip used in diagnostic system |
WO2012049316A1 (en) | 2010-10-15 | 2012-04-19 | Olink Ab | Dynamic range methods |
AU2011340630B2 (en) | 2010-12-06 | 2017-01-19 | Mycartis Nv | Biomarkers and parameters for hypertensive disorders of pregnancy |
WO2012106333A1 (en) | 2011-01-31 | 2012-08-09 | Esoterix Genetic Laboratories, Llc | Methods for enriching microparticles or nucleic acids using binding molecules |
GB201101621D0 (en) | 2011-01-31 | 2011-03-16 | Olink Ab | Method and product |
US8951996B2 (en) | 2011-07-28 | 2015-02-10 | Lipocine Inc. | 17-hydroxyprogesterone ester-containing oral compositions and related methods |
WO2013068475A1 (en) * | 2011-11-09 | 2013-05-16 | Roche Diagnostics Gmbh | Dynamic of sflt-1 or endoglin/plgf ratio as an indicator for imminent preeclampsia and/or hellp syndrome |
EP2812698B1 (en) | 2012-02-06 | 2020-10-28 | PerkinElmer Health Sciences Canada, Inc. | Dual-acceptor time-resolved-fret |
EP2847354A4 (en) | 2012-05-08 | 2015-12-30 | Univ Leland Stanford Junior | Methods and compositions for providing a preeclampsia assessment |
KR101996123B1 (en) | 2012-06-27 | 2019-07-03 | 에프. 호프만-라 로슈 아게 | MEANS AND METHODS APPLYING sFlt-1/PlGF OR ENDOGLIN/PlGF RATIO TO RULE-OUT ONSET OF PREECLAMPSIA WITHIN A CERTAIN TIME PERIOD |
WO2014036440A2 (en) | 2012-08-30 | 2014-03-06 | Ansh Labs Llc | Papp-a2 as a marker for monitoring, predicting and diagnosing preeclampsia |
WO2014066568A1 (en) | 2012-10-24 | 2014-05-01 | Winthrop-University Hospital | Non-invasive biomarker to identify subjects at risk of preterm delivery |
US20150330989A1 (en) * | 2012-11-15 | 2015-11-19 | The Brigham And Women's Hospital, Inc. | Method and system for diagnosing and treating preeclampsia |
EP2965088B1 (en) * | 2013-03-04 | 2018-12-05 | IQ Products B.V. | Prognostic marker to determine the risk for early-onset preeclampsia |
JP6639392B2 (en) * | 2013-12-03 | 2020-02-05 | セザンヌ ソシエテ パ アクシオンス シンプリフィエ | Method for selective measurement of placental growth factor 2 |
WO2015110624A1 (en) | 2014-01-24 | 2015-07-30 | Roche Diagnostics Gmbh | Prediction of postpartum hellp syndrome, postpartum eclampsia or postpartum preeclampsia |
US10281475B2 (en) | 2014-03-27 | 2019-05-07 | Wayne State University | Systems and methods to identify and treat subjects at risk for obstetrical complications |
CN107155350A (en) | 2014-07-30 | 2017-09-12 | 马修·库珀 | For diagnosing, prognosis and confirm pre-eclampsia method and composition |
WO2016132136A1 (en) * | 2015-02-18 | 2016-08-25 | Aston University | Diagnostic assay and treatment for preeclampsia |
WO2016134324A1 (en) | 2015-02-20 | 2016-08-25 | Neoteryx, Llc | Method and apparatus for acquiring blood for testing |
WO2016149759A1 (en) | 2015-03-23 | 2016-09-29 | Adelaide Research & Innovation Pty Ltd | Methods and systems for determining risk of a pregnancy complication occurring |
EP3502705B1 (en) | 2015-09-11 | 2020-09-09 | Universidad de los Andes | In vitro method for identifying a pregnancy related disease |
NL2016967B1 (en) | 2016-06-15 | 2017-12-21 | Iq Products B V | Markers and their ratio to determine the risk for early-onset preeclampsia. |
US20190353667A1 (en) | 2017-02-06 | 2019-11-21 | Astute Medical, Inc. | Methods and Compositions for Diagnosis and Prognosis of Renal Injury and Renal Failure |
US20190079097A1 (en) | 2017-09-13 | 2019-03-14 | Progenity, Inc. | Preeclampsia biomarkers and related systems and methods |
WO2019055661A1 (en) | 2017-09-13 | 2019-03-21 | Progenity, Inc. | Preeclampsia biomarkers and related systems and methods |
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JP2020533595A (en) | 2020-11-19 |
CN111094988A (en) | 2020-05-01 |
CA3075688A1 (en) | 2019-03-21 |
KR20200109293A (en) | 2020-09-22 |
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