SG11202001801PA - Method for separating eighteen components in traditional chinese medicine composition - Google Patents

Method for separating eighteen components in traditional chinese medicine composition

Info

Publication number
SG11202001801PA
SG11202001801PA SG11202001801PA SG11202001801PA SG11202001801PA SG 11202001801P A SG11202001801P A SG 11202001801PA SG 11202001801P A SG11202001801P A SG 11202001801PA SG 11202001801P A SG11202001801P A SG 11202001801PA SG 11202001801P A SG11202001801P A SG 11202001801PA
Authority
SG
Singapore
Prior art keywords
chinese medicine
traditional chinese
medicine composition
separating
eighteen components
Prior art date
Application number
SG11202001801PA
Inventor
Shuo Shen
chuangfeng Zhang
Dan Bi
Feng Wei
Yunbo Sun
Original Assignee
Shijiazhuang Yiling Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shijiazhuang Yiling Pharmaceutical Co Ltd filed Critical Shijiazhuang Yiling Pharmaceutical Co Ltd
Publication of SG11202001801PA publication Critical patent/SG11202001801PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • C07H1/06Separation; Purification
    • C07H1/08Separation; Purification from natural products
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/265Adsorption chromatography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/562Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
    • C07C45/565Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom by reaction with hexamethylene-tetramine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78Separation; Purification; Stabilisation; Use of additives
    • C07C45/79Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/56Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06Benzopyran radicals
    • C07H17/065Benzo[b]pyrans
    • C07H17/07Benzo[b]pyran-4-ones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/55Liquid-liquid separation; Phase separation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
SG11202001801PA 2017-09-05 2018-09-05 Method for separating eighteen components in traditional chinese medicine composition SG11202001801PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201710789895.5A CN109422780B (en) 2017-09-05 2017-09-05 Method for separating eighteen components in traditional Chinese medicine composition
PCT/CN2018/104148 WO2019047848A1 (en) 2017-09-05 2018-09-05 Method for separating eighteen components in traditional chinese medicine composition

Publications (1)

Publication Number Publication Date
SG11202001801PA true SG11202001801PA (en) 2020-03-30

Family

ID=65513453

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202001801PA SG11202001801PA (en) 2017-09-05 2018-09-05 Method for separating eighteen components in traditional chinese medicine composition

Country Status (6)

Country Link
US (1) US11458417B2 (en)
EP (1) EP3680248A4 (en)
KR (1) KR102404533B1 (en)
CN (1) CN109422780B (en)
SG (1) SG11202001801PA (en)
WO (1) WO2019047848A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112014481B (en) * 2019-05-29 2022-10-25 湖北梦阳药业股份有限公司 Detection method of raw white oral liquid fingerprint spectrum
CN111337586B (en) * 2020-01-09 2022-09-20 西南大学 Method for evaluating honeysuckle characteristics by using labeled flavonoid screened based on metabolome
CN114573539A (en) * 2020-12-02 2022-06-03 中国科学院大连化学物理研究所 Method for preparing compound Phellibaumin D from phellinus igniarius medicinal material
CN116004747A (en) * 2022-09-07 2023-04-25 福建农林大学 Method for extracting 2, 3-butanediol monoglucoside from Raffaelea lauricola
CN116626183B (en) * 2023-04-07 2024-02-06 湖南易能生物医药有限公司 Fingerprint construction method of traditional Chinese medicine compound containing radix scutellariae and application of fingerprint construction method

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1194752C (en) 2003-07-01 2005-03-30 河北以岭医药研究院有限公司 Anti-virus Chinese medicine composition and preparation process thereof
CN1318439C (en) * 2003-12-24 2007-05-30 天津市南开医院 Preparation method of amygdalin and its application in preparation of amygdalin preparation for promoting the blood circulation of heart, brain, pancreas and wound
CN100350916C (en) 2005-01-24 2007-11-28 王永钧 Extraction process of effective component for compound Chinese medicine composition of asiaticoside
CN101862391B (en) * 2009-04-17 2014-12-17 北京以岭药业有限公司 Application of Chinese medicinal composition in preparing medicament for treating human cases of bird flu
CN101797307B (en) 2010-04-09 2011-08-10 广州中医药大学 Phenethyl alcohol glycoside-containing callicarpa kochiana extractive and preparation method thereof
CN102727653B (en) * 2011-04-01 2015-09-09 北京中医药大学 The preparation method of the pharmaceutical composition of control acute coronary syndrome and active site thereof
CN103304609B (en) * 2012-03-10 2016-01-20 中国科学院广州生物医药与健康研究院 Houttuynine sodium bisulfite heterozygosis flavonoids and its production and use
CN103800523B (en) 2012-11-13 2018-09-25 河北以岭医药研究院有限公司 A kind of preparation method of anti virus herb composition and the assay method of finger-print
CN104547209A (en) * 2013-10-25 2015-04-29 石家庄以岭药业股份有限公司 Preparation method of traditional Chinese medicine composition
CN105287610B (en) * 2014-06-27 2021-11-16 石家庄以岭药业股份有限公司 Application of forsythoside I and preparation method thereof
CN104861015A (en) * 2015-01-16 2015-08-26 李玉山 Synergistic clean extraction method of effective components in licorice root
CN105461765B (en) 2015-11-25 2018-11-02 江苏康缘药业股份有限公司 A kind of preparation method of amarogentin

Also Published As

Publication number Publication date
CN109422780B (en) 2021-07-13
EP3680248A4 (en) 2021-06-16
US11458417B2 (en) 2022-10-04
EP3680248A1 (en) 2020-07-15
KR102404533B1 (en) 2022-06-02
KR20200040886A (en) 2020-04-20
WO2019047848A1 (en) 2019-03-14
US20200398188A1 (en) 2020-12-24
CN109422780A (en) 2019-03-05

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