SG11202000899PA - Anti-apelin antibodies and uses thereof - Google Patents
Anti-apelin antibodies and uses thereofInfo
- Publication number
- SG11202000899PA SG11202000899PA SG11202000899PA SG11202000899PA SG11202000899PA SG 11202000899P A SG11202000899P A SG 11202000899PA SG 11202000899P A SG11202000899P A SG 11202000899PA SG 11202000899P A SG11202000899P A SG 11202000899PA SG 11202000899P A SG11202000899P A SG 11202000899PA
- Authority
- SG
- Singapore
- Prior art keywords
- apelin
- antibodies
- apelin antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Biotechnology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Ophthalmology & Optometry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762549523P | 2017-08-24 | 2017-08-24 | |
| US201762579287P | 2017-10-31 | 2017-10-31 | |
| US201862656586P | 2018-04-12 | 2018-04-12 | |
| US201862658111P | 2018-04-16 | 2018-04-16 | |
| PCT/US2018/047144 WO2019040390A1 (en) | 2017-08-24 | 2018-08-21 | ANTI-APELIN ANTIBODIES AND USES THEREOF |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202000899PA true SG11202000899PA (en) | 2020-03-30 |
Family
ID=65440110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202000899PA SG11202000899PA (en) | 2017-08-24 | 2018-08-21 | Anti-apelin antibodies and uses thereof |
Country Status (12)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119613548A (zh) * | 2018-06-13 | 2025-03-14 | 鸿运华宁（杭州）生物医药有限公司 | APJ抗体及其与Elabela的融合蛋白质，以及其药物组合物和应用 |
| US20220220214A1 (en) * | 2019-06-19 | 2022-07-14 | Ab Initio Biotherapeutics, Inc. | Apj modulators and uses thereof |
| IL293868A (en) * | 2019-12-17 | 2022-08-01 | Phanes Therapeutics Inc | Bispecific antibodies with alternatively matched interchain cysteines and uses thereof |
| CN112442534B (zh) * | 2020-11-06 | 2022-03-15 | 温州医科大学 | 循环血外泌体miR-146a-5p作为视网膜静脉阻塞治疗及预后评估标志物中的应用 |
| CN114539415B (zh) * | 2020-11-24 | 2024-02-02 | 普米斯生物技术(珠海)有限公司 | 一种抗PD-L1/VEGF/TGF-β多特异性抗体及其用途 |
| CN112480267A (zh) * | 2020-12-04 | 2021-03-12 | 复旦大学附属华山医院 | 一种可特异性识别增殖状态内皮细胞的启动分子及工程细胞 |
| CN112546198B (zh) * | 2020-12-17 | 2022-03-25 | 温州医科大学慈溪生物医药研究院 | 一种用于治疗脑中风和急性脑梗的药物组合物 |
| CN114099642A (zh) * | 2021-11-12 | 2022-03-01 | 南通大学 | 基因Apln在制备治疗与细胞成血管有关疾病药物中的应用 |
| CN114031686A (zh) * | 2021-12-23 | 2022-02-11 | 杭州百凌生物科技有限公司 | 一种四型胶原蛋白ɑ5的抗体、检测试剂盒及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8946382B2 (en) * | 2009-02-27 | 2015-02-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Apelin peptides and methods of use |
| US9156911B2 (en) * | 2011-07-18 | 2015-10-13 | Amgen Inc. | Apelin antigen-binding proteins and uses thereof |
| EP2836510A1 (en) * | 2012-04-11 | 2015-02-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Polypeptides as apelin inhibitors and uses thereof |
| EA201591700A1 (ru) * | 2013-03-14 | 2015-12-30 | Ридженерон Фармасьютикалз, Инк. | Гибридные белки апелина и их применение |
| BR112015030892A2 (pt) | 2013-06-10 | 2017-08-29 | Merck Sharp & Dohme | Proteína de ligação ao antígeno, anticorpo monoclonal, ácido nucleico recombinante, vetor de expressão, célula hospedeira, composição farmacêutica, uso de uma proteína de ligação ao antígeno ou anticorpo humanizado, e, método para produzir uma proteína de ligação ao antígeno |
-
2018
- 2018-08-21 JP JP2020511350A patent/JP7219265B2/ja active Active
- 2018-08-21 EP EP18848958.7A patent/EP3672987B1/en active Active
- 2018-08-21 US US16/639,808 patent/US11365242B2/en active Active
- 2018-08-21 CA CA3072261A patent/CA3072261A1/en active Pending
- 2018-08-21 WO PCT/US2018/047144 patent/WO2019040390A1/en active IP Right Grant
- 2018-08-21 BR BR112020003584-0A patent/BR112020003584A2/pt not_active IP Right Cessation
- 2018-08-21 MX MX2020002042A patent/MX2020002042A/es unknown
- 2018-08-21 KR KR1020207008305A patent/KR20200038311A/ko not_active Withdrawn
- 2018-08-21 AU AU2018322452A patent/AU2018322452A1/en not_active Abandoned
- 2018-08-21 CN CN201880055019.2A patent/CN111032689B/zh active Active
- 2018-08-21 SG SG11202000899PA patent/SG11202000899PA/en unknown
-
2020
- 2020-02-05 IL IL272476A patent/IL272476A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019040390A1 (en) | 2019-02-28 |
| MX2020002042A (es) | 2020-08-13 |
| CN111032689A (zh) | 2020-04-17 |
| JP7219265B2 (ja) | 2023-02-07 |
| US20200362021A1 (en) | 2020-11-19 |
| BR112020003584A2 (pt) | 2020-09-01 |
| CN111032689B (zh) | 2024-02-27 |
| EP3672987A1 (en) | 2020-07-01 |
| US11365242B2 (en) | 2022-06-21 |
| IL272476A (en) | 2020-03-31 |
| KR20200038311A (ko) | 2020-04-10 |
| EP3672987B1 (en) | 2025-04-16 |
| AU2018322452A1 (en) | 2020-03-05 |
| CA3072261A1 (en) | 2019-02-28 |
| JP2020536492A (ja) | 2020-12-17 |
| EP3672987C0 (en) | 2025-04-16 |
| EP3672987A4 (en) | 2021-08-18 |
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