SG11201911572YA - Adenoviral vectors - Google Patents
Adenoviral vectorsInfo
- Publication number
- SG11201911572YA SG11201911572YA SG11201911572YA SG11201911572YA SG11201911572YA SG 11201911572Y A SG11201911572Y A SG 11201911572YA SG 11201911572Y A SG11201911572Y A SG 11201911572YA SG 11201911572Y A SG11201911572Y A SG 11201911572YA SG 11201911572Y A SG11201911572Y A SG 11201911572YA
- Authority
- SG
- Singapore
- Prior art keywords
- oxford
- international
- medawar
- avenue
- floor
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6009—Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
- C12N2810/6018—Adenoviridae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/005—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB
Abstract
FigureW O 20 19/02099 2 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 31 January 2019 (31.01.2019) WIPO I PCT omit liononoi Imo lII ow (10) International Publication Number WO 2019/020992 Al (51) International Patent Classification: C12N 7/00 (2006.01) (21) International Application Number: PCT/GB2018/052083 (22) International Filing Date: 24 July 2018 (24.07.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1711971.0 25 July 2017 (25.07.2017) GB 1806375.0 19 April 2018 (19.04.2018) GB (71) Applicant: OXFORD GENETICS LIMITED [GB/GB]; First Floor, Medawar 1, Robert Robinson Avenue, The Ox- ford Science Park, Oxford Oxfordshire OX4 4GA (GB). (72) Inventors: CAWOOD, Ryan; c/o Oxford Genetics Ltd, First Floor, Medawar 1, Robert Robinson Avenue, The Ox- ford Science Park, Oxford Oxfordshire OX4 4GA (GB). SU, Weiheng; c/o Oxford Genetics Ltd, First Floor, Medawar 1, Robert Robinson Avenue, The Oxford Science Park, Oxford Oxfordshire OX4 4GA (GB). (74) Agent: DEHNS; St Bride's House, 10 Salisbury Square, London Greater London EC4Y 8JD (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). — (54) Title: ADENOVIRAL VECTORS (57) : The present invention relates to an adenoviral vector com- prising a regulatable Major Late Promoter and an exogenous transgene. The invention also provides cells comprising such adenoviral vectors, and processes using such vectors. [Continued on next page] WO 2019/020992 Al MIDEDIMOMOIDIONOICIEHM01010110111011101011MOVOIMIE Published: — with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a))
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1711971.0A GB201711971D0 (en) | 2017-07-25 | 2017-07-25 | Vectors |
GBGB1806375.0A GB201806375D0 (en) | 2018-04-19 | 2018-04-19 | Vectors |
PCT/GB2018/052083 WO2019020992A1 (en) | 2017-07-25 | 2018-07-24 | Adenoviral vectors |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201911572YA true SG11201911572YA (en) | 2020-02-27 |
Family
ID=63077905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201911572YA SG11201911572YA (en) | 2017-07-25 | 2018-07-24 | Adenoviral vectors |
Country Status (10)
Country | Link |
---|---|
US (1) | US20200239909A1 (en) |
EP (1) | EP3658668A1 (en) |
JP (1) | JP7105866B2 (en) |
KR (1) | KR102609021B1 (en) |
CN (1) | CN110892064A (en) |
AU (1) | AU2018307569B2 (en) |
BR (1) | BR112019027765A2 (en) |
CA (1) | CA3070654C (en) |
SG (1) | SG11201911572YA (en) |
WO (1) | WO2019020992A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4031670A4 (en) * | 2019-09-16 | 2023-10-18 | Excepgen Inc. | Systems and methods for protein expression |
CN115298316A (en) | 2020-02-04 | 2022-11-04 | 牛津遗传学有限公司 | Method for producing adeno-associated virus vector |
GB202001484D0 (en) * | 2020-02-04 | 2020-03-18 | Oxford Genetics Ltd | DNA amplification method |
GB202013058D0 (en) | 2020-08-21 | 2020-10-07 | Oxford Genetics Ltd | Process for making a recombinant AAV library |
GB202013060D0 (en) | 2020-08-21 | 2020-10-07 | Oxford Genetics Ltd | Cell line |
GB202013057D0 (en) | 2020-08-21 | 2020-10-07 | Oxford Genetics Ltd | Method of making recombinant aavs |
WO2022038367A1 (en) | 2020-08-21 | 2022-02-24 | Oxford Genetics Limited | Process for making a recombinant aav library |
CN112501207B (en) * | 2020-12-07 | 2022-08-09 | 和元生物技术(上海)股份有限公司 | Adenovirus packaging method capable of realizing controllable expression of exogenous gene |
CN112501209B (en) * | 2020-12-07 | 2024-02-13 | 和元生物技术(上海)股份有限公司 | Method for packaging adeno-associated virus with controllable expression of exogenous gene |
WO2022223954A1 (en) | 2021-04-19 | 2022-10-27 | Oxford Genetics Limited | Dna amplification method using care elements |
GB202105581D0 (en) | 2021-04-19 | 2021-06-02 | Oxford Genetics Ltd | DNA amplification method |
EP4112731A1 (en) * | 2021-07-01 | 2023-01-04 | Charité - Universitätsmedizin Berlin | System for high-level raav production |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3875990B2 (en) * | 1993-10-25 | 2007-01-31 | カンジ,インコーポレイテッド | Recombinant adenoviral vectors and methods of use |
NZ502175A (en) * | 1998-04-15 | 2002-12-20 | Univ New York State Res Found | Selective regulation of adenovirus packaging with COUP-TF or lac repressor |
US6383794B1 (en) * | 1998-08-24 | 2002-05-07 | Uab Research Foundation | Methods of producing high titer recombinant adeno-associated virus |
HU226602B1 (en) | 1998-10-15 | 2009-04-28 | Canji | Selectively replicating viral vectors, pharmaceutical preparations containing them and process for producing them |
CN101035901A (en) * | 2004-07-22 | 2007-09-12 | 细胞基因系统有限公司 | Addition of transgenes into adenoviral vectors |
KR20080052512A (en) * | 2005-05-23 | 2008-06-11 | 박신, 인크. | Rapid production of adenovirus-free recombinant adenovirus vectors |
CN102533657B (en) * | 2010-12-28 | 2015-04-22 | 中国疾病预防控制中心病毒病预防控制所 | Human 41 type adenovirus (Ad41) packaging cell line and application thereof |
GB202001484D0 (en) * | 2020-02-04 | 2020-03-18 | Oxford Genetics Ltd | DNA amplification method |
-
2018
- 2018-07-24 WO PCT/GB2018/052083 patent/WO2019020992A1/en unknown
- 2018-07-24 EP EP18749100.6A patent/EP3658668A1/en active Pending
- 2018-07-24 AU AU2018307569A patent/AU2018307569B2/en active Active
- 2018-07-24 SG SG11201911572YA patent/SG11201911572YA/en unknown
- 2018-07-24 KR KR1020207004660A patent/KR102609021B1/en active IP Right Grant
- 2018-07-24 US US16/634,024 patent/US20200239909A1/en active Pending
- 2018-07-24 CN CN201880047035.7A patent/CN110892064A/en active Pending
- 2018-07-24 BR BR112019027765-0A patent/BR112019027765A2/en unknown
- 2018-07-24 JP JP2020503812A patent/JP7105866B2/en active Active
- 2018-07-24 CA CA3070654A patent/CA3070654C/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR102609021B1 (en) | 2023-12-06 |
WO2019020992A1 (en) | 2019-01-31 |
AU2018307569B2 (en) | 2022-03-10 |
JP2020533956A (en) | 2020-11-26 |
CA3070654A1 (en) | 2019-01-31 |
JP7105866B2 (en) | 2022-07-25 |
KR20200031141A (en) | 2020-03-23 |
CA3070654C (en) | 2021-07-27 |
EP3658668A1 (en) | 2020-06-03 |
US20200239909A1 (en) | 2020-07-30 |
AU2018307569A1 (en) | 2020-02-20 |
CN110892064A (en) | 2020-03-17 |
BR112019027765A2 (en) | 2020-07-14 |
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