SG11201909818SA - A medicament for the treatment of diseases by biofilm forming microorganisms - Google Patents

A medicament for the treatment of diseases by biofilm forming microorganisms

Info

Publication number
SG11201909818SA
SG11201909818SA SG11201909818SA SG11201909818SA SG 11201909818S A SG11201909818S A SG 11201909818SA SG 11201909818S A SG11201909818S A SG 11201909818SA SG 11201909818S A SG11201909818S A SG 11201909818SA
Authority
SG
Singapore
Prior art keywords
delhi
hauz
khas
kusuma
school
Prior art date
Application number
Inventor
Seyed Ehtesham Hasnain
Nasreen Zafar Ehtesham
Deeksha Tripathi
Sonam Grover
Ashutosh Kumar
Anwar Alam
Saurabh Pandey
Original Assignee
Indian Institute Of Technology Delhi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indian Institute Of Technology Delhi filed Critical Indian Institute Of Technology Delhi
Publication of SG11201909818SA publication Critical patent/SG11201909818SA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 25 October 2018 (25.10.2018) WIPO I PCT omit VIII °nolo Him olo Ho mo 10 1111111 ow (10) International Publication Number WO 2018/193477 Al W O 20 18/ 193 477 Al (51) International Patent Classification: A61K 35/76 (2015.01) (21) International Application Number: PCT/IN2018/050238 (22) International Filing Date: 20 April 2018 (20.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 201711014310 21 April 2017 (21.04.2017) IN (71) Applicant: INDIAN INSTITUTE OF TECHNOLOGY, DELHI [IN/IN]; Indian Institute of Technology Delhi Hauz Khas, New Delhi, Delhi 110 016 (IN). (72) Inventors: HASNAIN, Seyed Ehtesham; Kusuma School of Biological Sciences Indian Institute of Technology Del- hi Hauz Khas, New Delhi 110 016 (IN). EHTESHAM, Nasreen Zafar; National Institute of Pathology Safdarjang Hospital Campus, Ansari Nagar West, New Delhi 110029 (IN). TRIPATHI, Deeksha; Kusuma School of Biological Sciences Indian Institute of Technology Delhi Hauz Khas, New Delhi 110 016 (IN). GROVER, Sonam; Kusuma School of Biological Sciences Indian Institute of Technolo- gy Delhi Hauz Khas, New Delhi 110 016 (IN). KUMAR, Ashutosh; Kusuma School of Biological Sciences Indian Institute of Technology Delhi Hauz Khas, New Delhi 110 016 (IN). ALAM, Anwar; Kusuma School of Biological Sciences Indian Institute of Technology Delhi Hauz Khas, New Delhi 110 016 (IN). PANDEY, Saurabh; Kusuma School of Biological Sciences Indian Institute of Technolo- gy Delhi Hauz Khas, New Delhi 110 016 (IN). (74) Agent: LAKSHMIKUMARAN, Malathi et al.; B6/10, Safdarjung Enclave, New Delhi 110029 (IN). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: with international search report (Art. 21(3)) in black and white; the international application as filed contained color or greyscale and is available for download from PATENTSCOPE (54) Title: A MEDICAMENT FOR THE TREATMENT OF DISEASES BY BIOFILM FORMING MICROORGANISMS (57) : The present disclosure discloses a medicament comprising a drug selected from a group consisting of acarbose, cy- closporine A, its pharmaceutically acceptable salts thereof, and combinations thereof, for use in treatment of diseases caused by biofilm forming microorganisms. Also, provided herein are methods of treating diseases caused by biofilm forming microorganisms.
SG11201909818S 2017-04-21 2018-04-20 A medicament for the treatment of diseases by biofilm forming microorganisms SG11201909818SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201711014310 2017-04-21
PCT/IN2018/050238 WO2018193477A1 (en) 2017-04-21 2018-04-20 A medicament for the treatment of diseases by biofilm forming microorganisms

Publications (1)

Publication Number Publication Date
SG11201909818SA true SG11201909818SA (en) 2019-11-28

Family

ID=63855739

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201909818S SG11201909818SA (en) 2017-04-21 2018-04-20 A medicament for the treatment of diseases by biofilm forming microorganisms

Country Status (4)

Country Link
US (1) US20200188477A1 (en)
SG (1) SG11201909818SA (en)
WO (1) WO2018193477A1 (en)
ZA (1) ZA201907396B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020037260A1 (en) * 1997-10-16 2002-03-28 Budny John A. Compositions for treating biofilm
GB201003734D0 (en) * 2010-03-05 2010-04-21 Univ Strathclyde Delayed prolonged drug delivery

Also Published As

Publication number Publication date
ZA201907396B (en) 2020-07-29
WO2018193477A1 (en) 2018-10-25
US20200188477A1 (en) 2020-06-18

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