SG11201909228VA - Encapsulated nutritional and pharmaceutical compositions - Google Patents
Encapsulated nutritional and pharmaceutical compositionsInfo
- Publication number
- SG11201909228VA SG11201909228VA SG11201909228VA SG11201909228VA SG 11201909228V A SG11201909228V A SG 11201909228VA SG 11201909228V A SG11201909228V A SG 11201909228VA SG 11201909228V A SG11201909228V A SG 11201909228VA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- compositions
- pct
- encapsulated
- lcpufas
- Prior art date
Links
- 235000016709 nutrition Nutrition 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 4
- 102220547770 Inducible T-cell costimulator_A23L_mutation Human genes 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000000839 emulsion Substances 0.000 abstract 2
- 239000000416 hydrocolloid Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 241000132092 Aster Species 0.000 abstract 1
- 241000219501 Casuarina Species 0.000 abstract 1
- 241000219793 Trifolium Species 0.000 abstract 1
- 238000005538 encapsulation Methods 0.000 abstract 1
- 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 102220229106 rs753340463 Human genes 0.000 abstract 1
- 102220214412 rs886288172 Human genes 0.000 abstract 1
- 230000003019 stabilising effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
- A23D7/005—Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
- A23D7/0053—Compositions other than spreads
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
- A23D7/01—Other fatty acid esters, e.g. phosphatides
- A23D7/011—Compositions other than spreads
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/02—Other edible oils or fats, e.g. shortenings, cooking oils characterised by the production or working-up
- A23D9/04—Working-up
- A23D9/05—Forming free-flowing pieces
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/612—Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Marine Sciences & Fisheries (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Insects & Arthropods (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Edible Oils And Fats (AREA)
- General Preparation And Processing Of Foods (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 01 November 2018 (01.11.2018) WIPO I PCT 0111111010 0111 °nolo mu Kum IIl iflo oimIE (10) International Publication Number WO 2018/195601 Al (51) International Patent Classification: A23L 33/12 (2016.01) A61K 9/16 (2006.01) A23P 10/30 (2016.01) A23D 7/00 (2006.01) A23L 29/269 (2016.01) A61K 49/18 (2006.01) A61K 47/36 (2006.01) (21) International Application Number: PCT/AU2018/050384 (22) International Filing Date: 27 April 2018 (27.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 2017901524 27 April 2017 (27.04.2017) AU (71) Applicant: CLOVER CORPORATION LIMITED [AU/AU]; 39 Pinnacle Road, Altona North, Victoria 3025 (AU). (72) Inventors: WANG, Bo; 11 Inverary Place, Parkinson, Queensland 4115 (AU). CHENG, Mek Chu Ting; 12 Aster Place, Calamvale, Queensland 4116 (AU). ELLIOTT, Glenn; 18 Ebony Court, Casuarina, New South Wales 2487 (AU). (74) Agent: DAVIES COLLISON CAVE PTY LTD; 255 Elizabeth Street, Sydney, New South Wales 2000 (AU). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) O 00 O C (54) Title: ENCAPSULATED NUTRITIONAL AND PHARMACEUTICAL COMPOSITIONS (57) : Provided herein are encapsulated compositions comprising one or more long chain polyunsaturated fatty acids (LCPU- FAs) and at least one hydrocolloid, wherein the composition has a surface free fat content of less than about 5%. Also provided are methods for stabilising emulsions comprising one or more LCPUFAs and for increasing the efficiency of encapsulation of compositions comprising one or more LCPUFAs, the methods comprising incorporating at least one hydrocolloid into the emulsions or compositions.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2017901524A AU2017901524A0 (en) | 2017-04-27 | Encapsulated nutritional and pharmaceutical compositions | |
PCT/AU2018/050384 WO2018195601A1 (en) | 2017-04-27 | 2018-04-27 | Encapsulated nutritional and pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201909228VA true SG11201909228VA (en) | 2019-11-28 |
Family
ID=63917786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201909228V SG11201909228VA (en) | 2017-04-27 | 2018-04-27 | Encapsulated nutritional and pharmaceutical compositions |
Country Status (15)
Country | Link |
---|---|
US (1) | US20210093578A1 (en) |
EP (1) | EP3614865A4 (en) |
JP (2) | JP7458788B2 (en) |
KR (1) | KR20190142773A (en) |
CN (1) | CN110650636A (en) |
AU (1) | AU2018259160B2 (en) |
CA (1) | CA3062351A1 (en) |
CL (1) | CL2019003072A1 (en) |
IL (1) | IL270157B2 (en) |
MX (1) | MX2019012681A (en) |
NZ (1) | NZ757794A (en) |
PE (1) | PE20191794A1 (en) |
PH (1) | PH12019502410A1 (en) |
SG (1) | SG11201909228VA (en) |
WO (1) | WO2018195601A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20210045409A1 (en) * | 2019-08-13 | 2021-02-18 | Givaudan S.A. | Fat delivery system, fat delivery method and food product containing the fat delivery system |
KR102663920B1 (en) * | 2020-11-16 | 2024-05-07 | 성균관대학교산학협력단 | Method for preparing perilla oil powder |
WO2022200636A1 (en) * | 2021-03-26 | 2022-09-29 | Insucaps Limited | Pharmaceutical formulations, and methods for the production thereof |
KR102687020B1 (en) * | 2021-05-14 | 2024-07-22 | 허미진 | rTG Omega-3 Manufacturing Method |
EP4340801A1 (en) * | 2021-06-28 | 2024-03-27 | Lonza Greenwood LLC | Liquid filled capsule with two phase liquid fill |
CN117813016A (en) * | 2021-07-28 | 2024-04-02 | N·V·努特里奇亚 | Method for preparing a powder by spray drying and powder obtainable by the same |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006025769A (en) | 2004-07-13 | 2006-02-02 | Kosshi:Kk | Health food and method for maintaining health |
CN101115404B (en) * | 2005-02-02 | 2013-06-05 | 帝斯曼知识产权资产管理有限公司 | Powder compositions |
ATE430488T1 (en) | 2005-08-30 | 2009-05-15 | Firmenich & Cie | ENCAPSULATED ACTIVE INGREDIENTS, METHOD OF PREPARATION AND USE THEREOF |
DK2234502T4 (en) * | 2007-12-21 | 2021-10-11 | Basf Se | MICROCAPLES CONTAINING A FAT SOLUBLE ACTIVE SUBSTANCE |
NL2003224C2 (en) * | 2009-07-17 | 2011-01-18 | Friesland Brands Bv | Method for encapsulation of an edible oil, compositions comprising edible oil and the use thereof. |
EA026128B1 (en) * | 2010-04-09 | 2017-03-31 | ДСМ АйПи АССЕТС Б.В. | Thermally stable oil-in-water emulsion comprising an oil that comprises polyunsaturated fatty acids and process for preparing same |
HUE044068T2 (en) * | 2011-02-11 | 2019-09-30 | Clover Corporation Ltd | Nutritional compositions and uses thereof |
US20140154377A1 (en) | 2011-04-04 | 2014-06-05 | Dsm Ip Assets B.V. | Oil-in-water emulsions comprising a polyunsaturated fatty acid and methods of making the same |
US20130004617A1 (en) | 2011-07-01 | 2013-01-03 | Pepsico, Inc. | Coacervate complexes, methods and food products |
WO2013067603A1 (en) * | 2011-11-10 | 2013-05-16 | Clover Corporation Limited | Encapsulation of food ingredients supplements and pharmaceuticals |
EP2792247A1 (en) * | 2013-04-19 | 2014-10-22 | Laboratoires Meiners Sarl | Encapsulation of an Oil Containing Unsaturated Fatty Acids |
MX2016008287A (en) * | 2013-12-27 | 2016-09-08 | Nestec Sa | Composition comprising ferric saccharate and high concentrations of microencapsulated lc-pufa with a reduced off taste. |
GB201509606D0 (en) * | 2015-06-03 | 2015-07-15 | Anabio Technologies Ltd | Microencapsulates containing stabilised marine-derived oil, and methods for production thereof |
-
2018
- 2018-04-17 US US16/608,740 patent/US20210093578A1/en active Pending
- 2018-04-27 IL IL270157A patent/IL270157B2/en unknown
- 2018-04-27 KR KR1020197033236A patent/KR20190142773A/en not_active Application Discontinuation
- 2018-04-27 EP EP18790879.3A patent/EP3614865A4/en active Pending
- 2018-04-27 NZ NZ757794A patent/NZ757794A/en unknown
- 2018-04-27 WO PCT/AU2018/050384 patent/WO2018195601A1/en unknown
- 2018-04-27 MX MX2019012681A patent/MX2019012681A/en unknown
- 2018-04-27 JP JP2019558758A patent/JP7458788B2/en active Active
- 2018-04-27 CA CA3062351A patent/CA3062351A1/en active Pending
- 2018-04-27 SG SG11201909228V patent/SG11201909228VA/en unknown
- 2018-04-27 PE PE2019002108A patent/PE20191794A1/en unknown
- 2018-04-27 CN CN201880027740.0A patent/CN110650636A/en active Pending
- 2018-04-27 AU AU2018259160A patent/AU2018259160B2/en active Active
-
2019
- 2019-10-24 PH PH12019502410A patent/PH12019502410A1/en unknown
- 2019-10-25 CL CL2019003072A patent/CL2019003072A1/en unknown
-
2023
- 2023-12-14 JP JP2023211167A patent/JP2024023672A/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU2018259160A1 (en) | 2019-10-24 |
KR20190142773A (en) | 2019-12-27 |
IL270157B2 (en) | 2024-02-01 |
US20210093578A1 (en) | 2021-04-01 |
IL270157B1 (en) | 2023-10-01 |
CL2019003072A1 (en) | 2020-02-28 |
CA3062351A1 (en) | 2018-11-01 |
PH12019502410A1 (en) | 2020-10-19 |
EP3614865A1 (en) | 2020-03-04 |
IL270157A (en) | 2019-12-31 |
PE20191794A1 (en) | 2019-12-24 |
WO2018195601A1 (en) | 2018-11-01 |
JP7458788B2 (en) | 2024-04-01 |
AU2018259160B2 (en) | 2023-04-27 |
RU2019137892A3 (en) | 2021-12-09 |
RU2019137892A (en) | 2021-05-27 |
CN110650636A (en) | 2020-01-03 |
MX2019012681A (en) | 2019-12-11 |
NZ757794A (en) | 2023-05-26 |
JP2024023672A (en) | 2024-02-21 |
JP2020524482A (en) | 2020-08-20 |
EP3614865A4 (en) | 2021-05-05 |
BR112019022260A2 (en) | 2020-05-19 |
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