SG11201908136QA - Continuous countercurrent spiral chromatography - Google Patents

Continuous countercurrent spiral chromatography

Info

Publication number
SG11201908136QA
SG11201908136QA SG11201908136QA SG11201908136QA SG 11201908136Q A SG11201908136Q A SG 11201908136QA SG 11201908136Q A SG11201908136Q A SG 11201908136QA SG 11201908136Q A SG11201908136Q A SG 11201908136QA
Authority
SG
Singapore
Prior art keywords
stage
separator
international
pennsylvania
produce
Prior art date
Application number
Inventor
Oleg Shinkazh
Dmitriy Fedorenko
Original Assignee
Chromatan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chromatan Inc filed Critical Chromatan Inc
Publication of SG11201908136QA publication Critical patent/SG11201908136QA/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1892—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns the sorbent material moving as a whole, e.g. continuous annular chromatography, true moving beds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/42—Flow patterns using counter-current
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/58—Conditioning of the sorbent material or stationary liquid the sorbent moving as a whole
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/203—Equilibration or regeneration

Abstract

f 8 02 105 122 122 D>C 301 300 104 103 3 109 101 1-1 co co 00 O C (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 04 October 2018 (04.10.2018) W I PO I PCT omit °nolo HE mil mu mil ono oimIE (10) International Publication Number WO 2018/183483 Al (51) International Patent Classification: GO1N 30/42 (2006.01) BOlD 15/18 (2006.01) (21) International Application Number: PCT/US2018/024823 (22) International Filing Date: 28 March 2018 (28.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/477,917 28 March 2017 (28.03.2017) US (71) Applicant: CHROMATAN INC. [US/US]; 200 Innova- tion Blvd., Suite 260B, State College, Pennsylvania 16803 (US). (72) Inventors: SHINKAZH, Oleg; 200 Innovation Blvd., Suite 260B, State College, Pennsylvania 16803 (US). FE- DORENKO, Dmitriy; 200 Innovation Blvd., Suite 260B, State College, Pennsylvania 16803 (US). (74) Agent: MARCUS, David M. et al.; 100 Pine Street, P.O. Box 1166, Harrisburg, Pennsylvania 17108-1166 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (54) Title: CONTINUOUS COUNTERCURRENT SPIRAL CHROMATOGRAPHY FIG 4 (57) : A system, module and method for continuous countercurrent spiral chromatography are disclosed. The module includes an input port for receiving an input solution, a first mixer for mixing the input solution with a recycled solution to produce a first mixed output, a stage I separator for concentrating the first mixed output to produce a stage I solid fraction, a second mixer for mixing the stage I solid fraction from the stage I separator and an optional buffer solution to produce a second mixed output, and a stage II separator for concentrating the second mixed output to produce a stage II solid fraction which exits the module. At least one separator is a spiral separator. The system includes a plurality of modules, and at least one of the plurality of modules includes a spiral separator. The method includes purifying an unpurified solution with the plurality of modules. [Continued on next page] WO 2018/183483 Al MIDEDIMOMOIDEIREEMOMMENIVEMOVOIS GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))
SG11201908136Q 2017-03-28 2018-03-28 Continuous countercurrent spiral chromatography SG11201908136QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762477917P 2017-03-28 2017-03-28
PCT/US2018/024823 WO2018183483A1 (en) 2017-03-28 2018-03-28 Continuous countercurrent spiral chromatography

Publications (1)

Publication Number Publication Date
SG11201908136QA true SG11201908136QA (en) 2019-10-30

Family

ID=63678331

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201908136Q SG11201908136QA (en) 2017-03-28 2018-03-28 Continuous countercurrent spiral chromatography

Country Status (8)

Country Link
US (1) US11110374B2 (en)
EP (1) EP3602034A4 (en)
JP (2) JP2020520787A (en)
KR (1) KR102581732B1 (en)
CN (1) CN110462393B (en)
CA (1) CA3057681A1 (en)
SG (1) SG11201908136QA (en)
WO (1) WO2018183483A1 (en)

Families Citing this family (2)

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JP7434740B2 (en) * 2019-07-12 2024-02-21 株式会社Ihi Preparation system for test sample liquid and method for preparing test sample liquid
CN113608359B (en) * 2021-08-19 2023-08-11 中国科学院光电技术研究所 Mode-adjustable intracavity vortex beam generating device

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Also Published As

Publication number Publication date
WO2018183483A1 (en) 2018-10-04
JP2020520787A (en) 2020-07-16
JP2022188119A (en) 2022-12-20
US20200030717A1 (en) 2020-01-30
US11110374B2 (en) 2021-09-07
CA3057681A1 (en) 2018-10-04
CN110462393A (en) 2019-11-15
KR102581732B1 (en) 2023-09-21
EP3602034A1 (en) 2020-02-05
EP3602034A4 (en) 2020-12-30
KR20190127919A (en) 2019-11-13
CN110462393B (en) 2022-05-24

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