SG11201908052PA - Lipid-based nanoparticles with enhanced stability - Google Patents
Lipid-based nanoparticles with enhanced stabilityInfo
- Publication number
- SG11201908052PA SG11201908052PA SG11201908052PA SG11201908052PA SG11201908052PA SG 11201908052P A SG11201908052P A SG 11201908052PA SG 11201908052P A SG11201908052P A SG 11201908052PA SG 11201908052P A SG11201908052P A SG 11201908052PA SG 11201908052P A SG11201908052P A SG 11201908052PA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- pct
- lipid
- ohio
- english
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 20 September 2018 (20.09.2018) WIP0 I PCT mu °million °nolo om onoin looimmo oimIE (10) International Publication Number WO 2018/169954 Al (51) International Patent Classification: A61K 38/28 (2006.01) A61K 47/28 (2006.01) A61K 47/24 (2006.01) A61K 9/127 (2006.01) (21) International Application Number: PCT/US2018/022182 (22) International Filing Date: 13 March 2018 (13.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/470,478 13 March 2017 (13.03.2017) US (71) Applicant: SDG, INC. [US/US]; 10000 Cedar Avenue, Suite 6, Cleveland, Ohio 44106 (US). (72) Inventor: GEHO, W. Blair; 533 Beechwood Drive, Wooster, Ohio 44691 (US). (74) Agent: SILVA, Domingos J. et al.; Saul Ewing Arnstein & Lehr LLP, 1500 Market Street, 38th Floor, Philadelphia, Pennsylvania 19102 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: with international search report (Art. 21(3)) 71' 01 01 1-1 (54) Title: LIPID-BASED NANOPARTICLES WITH ENHANCED STABILITY ▪ (57) : The invention provides an improved lipid-based nanoparticle, which can be used to deliver a therapeutic agent to a O subject, such as but not limited to a mammal, such as but not limited to a human. In certain embodiments, the nanoparticle of the N invention has reduced aggregation properties as compared to those taught in the prior art. C
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762470478P | 2017-03-13 | 2017-03-13 | |
PCT/US2018/022182 WO2018169954A1 (en) | 2017-03-13 | 2018-03-13 | Lipid-based nanoparticles with enhanced stability |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201908052PA true SG11201908052PA (en) | 2019-09-27 |
Family
ID=63522523
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201908052PA SG11201908052PA (en) | 2017-03-13 | 2018-03-13 | Lipid-based nanoparticles with enhanced stability |
Country Status (12)
Country | Link |
---|---|
US (3) | US20210137838A1 (en) |
EP (1) | EP3595701A4 (en) |
JP (2) | JP7306718B2 (en) |
KR (1) | KR20190124269A (en) |
CN (1) | CN110612114A (en) |
AU (1) | AU2018236190A1 (en) |
BR (1) | BR112019018989A2 (en) |
CA (1) | CA3055561A1 (en) |
MX (1) | MX2019010852A (en) |
SG (1) | SG11201908052PA (en) |
WO (1) | WO2018169954A1 (en) |
ZA (1) | ZA201906043B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
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US8962015B2 (en) | 2007-09-28 | 2015-02-24 | Sdg, Inc. | Orally bioavailable lipid-based constructs |
US11077173B2 (en) | 2017-03-13 | 2021-08-03 | Sdg, Inc. | Lipid-based nanoparticles and methods using same |
KR20200106912A (en) * | 2018-01-05 | 2020-09-15 | 에스디지,인코포레이티드 | Composition comprising lipid-based nanoparticles for treating diabetes |
WO2020206250A1 (en) * | 2019-04-03 | 2020-10-08 | The Johns Hopkins University | Lipid nanoparticles as oral vehicles of immunotherapy |
CA3136665A1 (en) * | 2019-04-12 | 2020-10-15 | Sdg, Inc. | Lipid-based nanoparticles and use of same in optimized insulin dosing regimens |
WO2021070778A1 (en) * | 2019-10-10 | 2021-04-15 | 株式会社カネカ | Nanodisc |
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-
2018
- 2018-03-13 WO PCT/US2018/022182 patent/WO2018169954A1/en unknown
- 2018-03-13 BR BR112019018989A patent/BR112019018989A2/en unknown
- 2018-03-13 MX MX2019010852A patent/MX2019010852A/en unknown
- 2018-03-13 AU AU2018236190A patent/AU2018236190A1/en active Pending
- 2018-03-13 CA CA3055561A patent/CA3055561A1/en active Pending
- 2018-03-13 SG SG11201908052PA patent/SG11201908052PA/en unknown
- 2018-03-13 CN CN201880028804.9A patent/CN110612114A/en active Pending
- 2018-03-13 EP EP18766906.4A patent/EP3595701A4/en active Pending
- 2018-03-13 US US16/491,834 patent/US20210137838A1/en not_active Abandoned
- 2018-03-13 KR KR1020197028580A patent/KR20190124269A/en not_active Application Discontinuation
- 2018-03-13 JP JP2020500002A patent/JP7306718B2/en active Active
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2019
- 2019-09-06 US US16/563,119 patent/US11071715B2/en active Active
- 2019-09-12 ZA ZA2019/06043A patent/ZA201906043B/en unknown
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2023
- 2023-02-01 US US18/104,620 patent/US20230172868A1/en active Pending
- 2023-06-22 JP JP2023102473A patent/JP2023120371A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2018236190A1 (en) | 2019-09-26 |
CN110612114A (en) | 2019-12-24 |
US20210137838A1 (en) | 2021-05-13 |
KR20190124269A (en) | 2019-11-04 |
US20230172868A1 (en) | 2023-06-08 |
JP2020510705A (en) | 2020-04-09 |
BR112019018989A2 (en) | 2020-04-14 |
JP7306718B2 (en) | 2023-07-11 |
EP3595701A1 (en) | 2020-01-22 |
WO2018169954A1 (en) | 2018-09-20 |
JP2023120371A (en) | 2023-08-29 |
EP3595701A4 (en) | 2021-01-06 |
ZA201906043B (en) | 2022-11-30 |
CA3055561A1 (en) | 2018-09-20 |
MX2019010852A (en) | 2019-10-30 |
US20200022922A1 (en) | 2020-01-23 |
US11071715B2 (en) | 2021-07-27 |
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