SG11201906301UA - Methods of manufacture of nut flours and formulations for oral immunotherapy - Google Patents

Methods of manufacture of nut flours and formulations for oral immunotherapy

Info

Publication number
SG11201906301UA
SG11201906301UA SG11201906301UA SG11201906301UA SG11201906301UA SG 11201906301U A SG11201906301U A SG 11201906301UA SG 11201906301U A SG11201906301U A SG 11201906301UA SG 11201906301U A SG11201906301U A SG 11201906301UA SG 11201906301U A SG11201906301U A SG 11201906301UA
Authority
SG
Singapore
Prior art keywords
international
formulations
nut
methods
manufacture
Prior art date
Application number
SG11201906301UA
Inventor
Reyna Simon
Nicholas Birringer
Original Assignee
Aimmune Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aimmune Therapeutics Inc filed Critical Aimmune Therapeutics Inc
Publication of SG11201906301UA publication Critical patent/SG11201906301UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L25/00Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
    • A23L25/30Mashed or comminuted products, e.g. pulp, pastes, meal, powders; Products made therefrom, e.g. blocks, flakes, snacks; Liquid or semi-liquid products
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 19 July 2018 (19.07.2018) WIP0 1 PCT omitia °nolo 011101110100111H 0111111 oimIE (10) International Publication Number WO 2018/132733 Al (51) International Patent Classification: A23L 5/20 (2016.01) A23L 7/10 (2016.01) (21) International Application Number: PCT/US2018/013612 (22) International Filing Date: 12 January 2018 (12.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/446,147 13 January 2017 (13.01.2017) US (71) Applicant: AIMMUNE THERAPEUTICS, INC. [US/US]; 8000 Marina Boulevard, Suite 200, Brisbane, CA 94005-1884 (US). (72) Inventors: SIMON, Reyna, Joy; c/o Aimmune Therapeu- tics, Inc., 8000 Marina Boulevard, Suite 200, Brisbane, CA 94005-1884 (US). BIRRINGER, Nicholas, William; c/o Aimmune Therapeutics, Inc., 8000 Marina Boulevard, Suite 200, Brisbane, CA 94005-1884 (US). (74) Agent: WEINER, Ethan, M. et al.; Morrison & Foerster LLP, 755 Page Mill Road, Palo Alto, CA 94304-1018 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) 11 N 11 00 11 O C (54) Title: METHODS OF MANUFACTURE OF NUT FLOURS AND FORMULATIONS FOR ORAL IMMUNOTHERAPY (57) : The present technology relates generally to methods of manufacture of nut flours and/or formulations, ultra-low fat nut flours and uses for nut flour formulations. In particular, several embodiments are directed to methods of manufacturing ultra-low fat tree nut or peanut flour formulations for oral administration in immunotherapy of subjects affected by allergies.
SG11201906301UA 2017-01-13 2018-01-12 Methods of manufacture of nut flours and formulations for oral immunotherapy SG11201906301UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762446147P 2017-01-13 2017-01-13
PCT/US2018/013612 WO2018132733A1 (en) 2017-01-13 2018-01-12 Methods of manufacture of nut flours and formulations for oral immunotherapy

Publications (1)

Publication Number Publication Date
SG11201906301UA true SG11201906301UA (en) 2019-08-27

Family

ID=62838507

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201913846XA SG10201913846XA (en) 2017-01-13 2018-01-12 Methods of manufacture of nut flours and formulations for oral immunotherapy
SG11201906301UA SG11201906301UA (en) 2017-01-13 2018-01-12 Methods of manufacture of nut flours and formulations for oral immunotherapy

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201913846XA SG10201913846XA (en) 2017-01-13 2018-01-12 Methods of manufacture of nut flours and formulations for oral immunotherapy

Country Status (10)

Country Link
US (2) US20180200361A1 (en)
EP (1) EP3568027A4 (en)
JP (2) JP2020514306A (en)
CN (1) CN110381749A (en)
AU (2) AU2018207167A1 (en)
CA (1) CA3050093A1 (en)
IL (1) IL267882A (en)
MX (1) MX2019008419A (en)
SG (2) SG10201913846XA (en)
WO (1) WO2018132733A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2924349B1 (en) 2007-12-03 2010-01-01 Dbv Tech ALLERGEN DISENSIBILITY METHOD
US9492535B2 (en) 2013-03-14 2016-11-15 Aimmune Therapeutics, Inc. Peanut formulations and uses thereof
EP3482771B1 (en) 2013-03-14 2023-01-18 Société des Produits Nestlé S.A. Manufacture of peanut formulations for oral desensitization
WO2016033094A1 (en) 2014-08-25 2016-03-03 Aimmune Therapeutics, Inc. Egg protein formulations and methods of manufacture thereof
US11452774B2 (en) 2015-02-20 2022-09-27 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US10166286B2 (en) 2015-02-20 2019-01-01 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US10149904B2 (en) 2015-02-20 2018-12-11 The Board Of Trusteees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
SG11202000419QA (en) 2017-07-18 2020-02-27 Before Brands Inc Methods for making mixed allergen compositions
MX2020004683A (en) 2017-11-02 2020-08-13 Aimmune Therapeutics Inc Methods of oral immunotherapy.
CN112638413A (en) 2018-07-27 2021-04-09 艾慕恩治疗公司 Oral immunotherapy unit dose dispensing systems and methods
EP3914098A1 (en) 2019-01-23 2021-12-01 Before Brands, Inc. Methods for making mixed allergen compositions
CN113966229A (en) 2019-05-10 2022-01-21 爱沐疗法公司 Method for improving the quality of life of peanut allergic patients
US20230330169A1 (en) * 2019-12-23 2023-10-19 Prota Therapeutics Pty Ltd Pharmaceutical compositions
CN112890199B (en) * 2021-02-27 2022-05-31 中国农业科学院油料作物研究所 Composition for stably and efficiently regulating immunologic function and preparation and application thereof
US20240151702A1 (en) * 2021-03-05 2024-05-09 Societe Des Produits Nestle S.A. Methods of making and assessing allergenic tree nut compositions

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU641135B2 (en) * 1990-01-08 1993-09-16 Procter & Gamble Company, The Improved nut butter and nut solid milling process
US20120164306A1 (en) * 1993-08-03 2012-06-28 Girsh Leonard S Process for preparing hypoallergenic and reduced fat foods
US6197356B1 (en) * 1993-08-03 2001-03-06 Immunopath Profile, Inc. Process for preparing hypoallergenic foods
US7381434B2 (en) * 2003-04-08 2008-06-03 Herbalscience Llc Methods and compositions of Areca catechu
BRPI0708505A2 (en) * 2006-03-03 2011-05-31 Specialty Protein Producers Inc fat separation processes from soybean materials and compositions produced therefrom
JP2012240975A (en) * 2011-05-20 2012-12-10 Nitto Denko Corp Pharmaceutical composition and jerry-form preparation
WO2013087119A1 (en) * 2011-12-16 2013-06-20 Hal Allergy Holding B.V. Pharmaceutical formulations and the use thereof for the treatment of peanut allergy
EP3482771B1 (en) * 2013-03-14 2023-01-18 Société des Produits Nestlé S.A. Manufacture of peanut formulations for oral desensitization
CN103535508A (en) * 2013-10-22 2014-01-29 陕西天玉实业有限公司 \Walnut protein powder and preparation method thereof
PL3258962T3 (en) * 2015-02-20 2023-04-24 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
CN106165870B (en) * 2016-07-08 2020-03-31 北京市农林科学院 Walnut defatted whole powder and preparation method and application thereof

Also Published As

Publication number Publication date
CA3050093A1 (en) 2018-07-19
US20180200361A1 (en) 2018-07-19
JP2022136170A (en) 2022-09-15
CN110381749A (en) 2019-10-25
SG10201913846XA (en) 2020-03-30
IL267882A (en) 2019-09-26
AU2018207167A1 (en) 2019-07-25
US20230233672A1 (en) 2023-07-27
JP2020514306A (en) 2020-05-21
WO2018132733A1 (en) 2018-07-19
MX2019008419A (en) 2019-12-02
EP3568027A4 (en) 2020-11-11
EP3568027A1 (en) 2019-11-20
AU2023202625A1 (en) 2023-05-18

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