SG11201903622QA - Adherent cell culture substrate sampling device - Google Patents

Adherent cell culture substrate sampling device

Info

Publication number
SG11201903622QA
SG11201903622QA SG11201903622QA SG11201903622QA SG11201903622QA SG 11201903622Q A SG11201903622Q A SG 11201903622QA SG 11201903622Q A SG11201903622Q A SG 11201903622QA SG 11201903622Q A SG11201903622Q A SG 11201903622QA SG 11201903622Q A SG11201903622Q A SG 11201903622QA
Authority
SG
Singapore
Prior art keywords
international
cell culture
rule
adherent cell
pct
Prior art date
Application number
SG11201903622QA
Inventor
Vesa Turkki
Original Assignee
Trizell Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trizell Ltd filed Critical Trizell Ltd
Publication of SG11201903622QA publication Critical patent/SG11201903622QA/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/12—Apparatus for enzymology or microbiology with sterilisation, filtration or dialysis means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/04—Seals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates

Abstract

4 W O 20 18/087 690 Al FIGURE 1 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 17 May 2018 (17.05.2018) WIPO I PCT ~~~~~~~~~~~~~ 011101VIIIVIIIVIII olo omm VIII iflo Hs (10) International Publication Number WO 2018/087690 Al (51) International Patent Classification: C12M 1/12 (2006.01) Cl 2M 1/26 (2006.01) (21) International Application Number: PCT/IB2017/057008 (22) International Filing Date: 09 November 2017 (09.11.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/419,613 09 November 2016 (09.11.2016) US (71) Applicant: TRIZELL LTD. [GB/GB]; Sanderum House Oakley Road, Chinnor, Oxfordshire OX39 4TW (GB). (72) Inventor: TURKKI, Vesa; Microkatu 1S, Kuopio (FI). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: as to the identity of the inventor (Rule 4.17(i)) as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(ii)) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) of inventorship (Rule 4.17(iv)) Published: — with international search report (Art. 21(3)) (54) Title: ADHERENT CELL CULTURE SUBSTRATE SAMPLING DEVICE (57) : A device for aseptically obtaining a physical sample of an adherent cell culture substrate from an adherent cell culture biore- actor. This enables the operator to directly evaluate e.g., cell density / confluence on the substrate without contaminating the cell culture.
SG11201903622QA 2016-11-09 2017-11-09 Adherent cell culture substrate sampling device SG11201903622QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662419613P 2016-11-09 2016-11-09
PCT/IB2017/057008 WO2018087690A1 (en) 2016-11-09 2017-11-09 Adherent cell culture substrate sampling device

Publications (1)

Publication Number Publication Date
SG11201903622QA true SG11201903622QA (en) 2019-05-30

Family

ID=60421830

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201903622QA SG11201903622QA (en) 2016-11-09 2017-11-09 Adherent cell culture substrate sampling device

Country Status (9)

Country Link
US (1) US11932843B2 (en)
EP (1) EP3538639A1 (en)
JP (1) JP7016371B2 (en)
KR (1) KR102506395B1 (en)
CN (1) CN110088264B (en)
AU (1) AU2017356664B2 (en)
IL (1) IL266485B1 (en)
SG (1) SG11201903622QA (en)
WO (1) WO2018087690A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102506395B1 (en) 2016-11-09 2023-03-03 트리젤 엘티디. Adherent cell culture-based sampling device
WO2021097366A1 (en) * 2019-11-15 2021-05-20 City Of Hope System, device and method for production of bioproduct including high density cell respirator for intensified production of adeno-associated viruses

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DE19528871C2 (en) * 1994-08-24 1997-08-14 Forschungszentrum Juelich Gmbh Fumigation tube module with selectively gas-permeable hose membranes and reactors provided with them for cell culture technology as well as fluidized bed reactors for cell cultivation
JP2004500158A (en) * 1999-07-29 2004-01-08 キュアリス・インコーポレーテッド Storage package
US7435587B2 (en) 2002-03-01 2008-10-14 Memorial Sloan-Kettering Cancer Center Apparatus for growing cells under variable hydrostatic pressures
KR100489903B1 (en) * 2003-08-08 2005-05-17 주식회사 네오바이오 Sterlized cutting and transfer system of plant and annimal cells and tissues and micro organism from small scale bio-reactor to large scale bio-reactor
FI20045231A0 (en) * 2004-06-18 2004-06-18 Bio Nobile Oy Method and apparatus for sampling and dispensing
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EP2739978A4 (en) * 2011-08-07 2014-12-24 Amir Hadayer Sterile sample injector and method
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KR102506395B1 (en) 2016-11-09 2023-03-03 트리젤 엘티디. Adherent cell culture-based sampling device

Also Published As

Publication number Publication date
CN110088264B (en) 2023-03-21
US20200172847A1 (en) 2020-06-04
AU2017356664B2 (en) 2022-01-13
WO2018087690A1 (en) 2018-05-17
RU2019117396A3 (en) 2021-02-20
RU2019117396A (en) 2020-12-10
JP2019533482A (en) 2019-11-21
EP3538639A1 (en) 2019-09-18
US11932843B2 (en) 2024-03-19
CN110088264A (en) 2019-08-02
KR102506395B1 (en) 2023-03-03
AU2017356664A1 (en) 2019-05-16
IL266485B1 (en) 2024-01-01
IL266485A (en) 2019-07-31
KR20190076042A (en) 2019-07-01
JP7016371B2 (en) 2022-02-21

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