SG11201900589PA - Methods for gynecologic neoplasm diagnosis - Google Patents
Methods for gynecologic neoplasm diagnosisInfo
- Publication number
- SG11201900589PA SG11201900589PA SG11201900589PA SG11201900589PA SG11201900589PA SG 11201900589P A SG11201900589P A SG 11201900589PA SG 11201900589P A SG11201900589P A SG 11201900589PA SG 11201900589P A SG11201900589P A SG 11201900589PA SG 11201900589P A SG11201900589P A SG 11201900589PA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- gynecologic
- pct
- methods
- english
- Prior art date
Links
- 208000009849 Female Genital Neoplasms Diseases 0.000 title abstract 4
- 208000028149 female reproductive system neoplasm Diseases 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000006607 hypermethylation Effects 0.000 abstract 1
- 230000036210 malignancy Effects 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57442—Specifically defined cancers of the uterus and endometrial
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/12—Post-translational modifications [PTMs] in chemical analysis of biological material alkylation, e.g. methylation, (iso-)prenylation, farnesylation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
AW O 18/0 19 29 4 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 01 February 2018 (01.02.2018) WIP0 I PCT °mons °nolo olumiolommommo (10) International Publication Number WO 2018/019294 Al (51) International Patent Classification: A61K 48/00 (2006.01) GO1N 33/483 (2006.01) G01N 33/48 (2006.01) G01N 33/50 (2006.01) (21) International Application Number: PCT/CN2017/094917 (22) International Filing Date: 28 July 2017 (28.07.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/368,182 29 July 2016 (29.07.2016) US (72) Inventor; and (71) Applicant: LAI, Hung-Cheng [CN/CN]; 5F., No.169, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City, Taiwan 114 (CN). (74) Agent: CHINA ZHENGHE INTELLECTUAL PROP- ERTY AGENCY; Unit C7, Floor 17, Block 2, Xihuan Plaza No. 1, Xizhimenwai Street, Xicheng District, Beijing 100044 (CN). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a)) (54) Title: METHODS FOR GYNECOLOGIC NEOPLASM DIAGNOSIS (57) : Disclosed herein are various methods for assessing the pres- ence of gynecologic neoplasm or the malignancy of the gynecologic neo- plasm, based on the hypermethylation of one or more marker genes. FIG. 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662368182P | 2016-07-29 | 2016-07-29 | |
| PCT/CN2017/094917 WO2018019294A1 (en) | 2016-07-29 | 2017-07-28 | Methods for gynecologic neoplasm diagnosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201900589PA true SG11201900589PA (en) | 2019-02-27 |
Family
ID=61015645
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201900589PA SG11201900589PA (en) | 2016-07-29 | 2017-07-28 | Methods for gynecologic neoplasm diagnosis |
| SG10202101024UA SG10202101024UA (en) | 2016-07-29 | 2017-07-28 | Methods for gynecologic neoplasm diagnosis |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202101024UA SG10202101024UA (en) | 2016-07-29 | 2017-07-28 | Methods for gynecologic neoplasm diagnosis |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20190153544A1 (en) |
| EP (1) | EP3490612A4 (en) |
| JP (3) | JP6767512B2 (en) |
| KR (1) | KR102258887B1 (en) |
| CN (1) | CN109069670B (en) |
| AU (1) | AU2017304949A1 (en) |
| BR (1) | BR112019001712A2 (en) |
| CA (1) | CA3032038A1 (en) |
| IL (1) | IL264542B2 (en) |
| MX (1) | MX2019001214A (en) |
| NZ (1) | NZ750327A (en) |
| RU (1) | RU2723531C1 (en) |
| SG (2) | SG11201900589PA (en) |
| TW (1) | TWI648403B (en) |
| WO (1) | WO2018019294A1 (en) |
| ZA (1) | ZA201900570B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113337614A (en) * | 2021-08-05 | 2021-09-03 | 北京起源聚禾生物科技有限公司 | Marker, primer probe and kit for early screening and diagnosis of endometrial cancer |
| EP4130297A1 (en) * | 2021-08-05 | 2023-02-08 | Beijing OriginPoly Bio-Tec Co., Ltd. | Markers, primers, probes and kit for early screening and diagnosis of endometrial cancer |
| EP4265738A1 (en) | 2022-03-03 | 2023-10-25 | Beijing OriginPoly Bio-Tec Co., Ltd. | Dna methylation marker combination, use, primer probe for early detection of ovarian cancer and kit |
| CN115725591A (en) * | 2022-09-22 | 2023-03-03 | 上海奕谱生物科技有限公司 | Novel tumor detection marker TAGMe and application thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1953748A (en) * | 2004-05-12 | 2007-04-25 | 生物如恩克斯株式会社 | A therapeutic agent containing nicotinic acid or its derivatives as an effective ingredient for prevention and treatment of cancer |
| US7754428B2 (en) * | 2006-05-03 | 2010-07-13 | The Chinese University Of Hong Kong | Fetal methylation markers |
| CN101230399B (en) * | 2008-01-07 | 2010-06-02 | 中国科学院化学研究所 | Method for detecting DNA methylation |
| CN101570779B (en) * | 2008-04-29 | 2016-02-17 | 赖鸿政 | A kind of method of cancer screening |
| CN105224827B (en) * | 2008-07-01 | 2019-12-24 | 小利兰·斯坦福大学托管委员会 | Computer system and storage medium for developing analytical data for IVF treatment protocols |
| CN101864480B (en) * | 2009-04-17 | 2013-12-18 | 国防医学院 | Cancer screening method |
| US20110195848A1 (en) * | 2010-01-08 | 2011-08-11 | Roopra Avtar S | Gene expression and breast cancer |
| EP2683834B1 (en) * | 2011-03-10 | 2017-12-06 | Oslo Universitetssykehus HF | Methods and biomarkers for detection of gastrointestinal cancers |
| AU2012301937A1 (en) * | 2011-08-30 | 2014-03-27 | National Defense Medical Center | Gene biomarkers for prediction of susceptibility of ovarian neoplasms and/or prognosis or malignancy of ovarian cancers |
| WO2013174432A1 (en) * | 2012-05-24 | 2013-11-28 | Fundació Institut D'investigació Biomèdica De Bellvitge (Idibell) | Method for the identification of the origin of a cancer of unknown primary origin by methylation analysis |
| ES2701742T3 (en) * | 2012-10-29 | 2019-02-25 | Univ Johns Hopkins | Papanicolaou test for ovarian and endometrial cancers |
| CN104513851B (en) * | 2013-10-08 | 2017-01-11 | 陈永恩 | Novel epigenetic biomarker for detecting bladder cancer and method thereof |
| EP3126529B1 (en) * | 2014-03-31 | 2020-05-27 | Mayo Foundation for Medical Education and Research | Detecting colorectal neoplasm |
| WO2016049024A2 (en) * | 2014-09-24 | 2016-03-31 | The Broad Institute Inc. | Delivery, use and therapeutic applications of the crispr-cas systems and compositions for modeling competition of multiple cancer mutations in vivo |
| WO2016115354A1 (en) * | 2015-01-14 | 2016-07-21 | Taipei Medical University | Methods for cancer diagnosis and prognosis |
-
2017
- 2017-07-27 TW TW106125367A patent/TWI648403B/en active
- 2017-07-28 MX MX2019001214A patent/MX2019001214A/en unknown
- 2017-07-28 BR BR112019001712-7A patent/BR112019001712A2/en unknown
- 2017-07-28 CN CN201780015221.8A patent/CN109069670B/en active Active
- 2017-07-28 JP JP2018563103A patent/JP6767512B2/en active Active
- 2017-07-28 SG SG11201900589PA patent/SG11201900589PA/en unknown
- 2017-07-28 NZ NZ750327A patent/NZ750327A/en unknown
- 2017-07-28 RU RU2019105547A patent/RU2723531C1/en active
- 2017-07-28 EP EP17833597.2A patent/EP3490612A4/en active Pending
- 2017-07-28 KR KR1020197002674A patent/KR102258887B1/en active IP Right Grant
- 2017-07-28 US US16/321,238 patent/US20190153544A1/en not_active Abandoned
- 2017-07-28 IL IL264542A patent/IL264542B2/en unknown
- 2017-07-28 WO PCT/CN2017/094917 patent/WO2018019294A1/en unknown
- 2017-07-28 AU AU2017304949A patent/AU2017304949A1/en active Pending
- 2017-07-28 SG SG10202101024UA patent/SG10202101024UA/en unknown
- 2017-07-28 CA CA3032038A patent/CA3032038A1/en active Pending
-
2019
- 2019-01-28 ZA ZA201900570A patent/ZA201900570B/en unknown
-
2020
- 2020-09-15 JP JP2020154865A patent/JP6971502B2/en active Active
-
2021
- 2021-10-26 JP JP2021174475A patent/JP7182317B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| NZ750327A (en) | 2022-07-29 |
| CN109069670A (en) | 2018-12-21 |
| JP7182317B2 (en) | 2022-12-02 |
| JP2019524058A (en) | 2019-09-05 |
| US20190153544A1 (en) | 2019-05-23 |
| JP2021019587A (en) | 2021-02-18 |
| SG10202101024UA (en) | 2021-03-30 |
| KR102258887B1 (en) | 2021-06-01 |
| IL264542A (en) | 2019-05-30 |
| AU2017304949A1 (en) | 2019-02-21 |
| CN109069670B (en) | 2022-05-10 |
| ZA201900570B (en) | 2019-10-30 |
| KR20190025941A (en) | 2019-03-12 |
| CA3032038A1 (en) | 2018-02-01 |
| IL264542B2 (en) | 2024-02-01 |
| WO2018019294A1 (en) | 2018-02-01 |
| MX2019001214A (en) | 2019-09-19 |
| JP2022036935A (en) | 2022-03-08 |
| JP6767512B2 (en) | 2020-10-14 |
| RU2723531C1 (en) | 2020-06-16 |
| TWI648403B (en) | 2019-01-21 |
| TW201805433A (en) | 2018-02-16 |
| IL264542B1 (en) | 2023-10-01 |
| EP3490612A1 (en) | 2019-06-05 |
| EP3490612A4 (en) | 2020-04-01 |
| JP6971502B2 (en) | 2021-11-24 |
| BR112019001712A2 (en) | 2019-05-07 |
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