SG11201807766YA - Prenylation assay - Google Patents
Prenylation assayInfo
- Publication number
- SG11201807766YA SG11201807766YA SG11201807766YA SG11201807766YA SG11201807766YA SG 11201807766Y A SG11201807766Y A SG 11201807766YA SG 11201807766Y A SG11201807766Y A SG 11201807766YA SG 11201807766Y A SG11201807766Y A SG 11201807766YA SG 11201807766Y A SG11201807766Y A SG 11201807766YA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- nuffield
- pct
- rab
- headley
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
- C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
- C12Y205/0106—Protein geranylgeranyltransferase type II (2.5.1.60)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/9116—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
- G01N2333/91165—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5) general (2.5.1)
- G01N2333/91171—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5) general (2.5.1) with definite EC number (2.5.1.-)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD 1101111 II 11101 HOE 010 1111 1 0 111 01 MHO HO HO RIMINI 011 International Bureau 0.. .... .. (10) International Publication Number (43) International Publication Date ...... ... WO 2017/153774 Al 14 September 2017 (14.09.2017) WIP0 I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every C12Q 1/48 (2006.01) kind AO, of national protection available): AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, PCT/GB2017/050659 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, 10 March 2017 (10.03.2017) KP, MD, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (25) Filing Language: English NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (26) Publication Language: English RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (30) Priority Data: ZA, ZM, ZW. 1604146.9 10 March 2016 (10.03.2016) GB (84) Designated States (unless otherwise indicated, for every (71) Applicant: NIGHTSTARX LIMITED [GB/GB]; Gibbs kind Building, 215 Euston Road, London NW1 2BE (GB). GM, of regional protection available): ARIPO (BW, GH, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, (72) Inventors: MACLAREN, Robert E.; Nuffield Laboratory TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), of Ophthalmology, Nuffield Department of Clinical Neur- osciences, Level 6, West Wing, John Radcliffe Hospital, DK, European (AL, AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, _ LV, Headley Way, Oxford Oxfordshire OX3 9DU (GB). MOR- SM, EIRA PATRICIO, Maria Ines; Nuffield Laboratory of GW, KM, ML, MR, NE, SN, TD, TG). Ophthalmology, Nuffield Department of Clinical Neuros- ciences, Level 6, West Wing, John Radcliffe Hospital, Published: MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, _ — Headley Way, Oxford Oxfordshire OX3 9DU (GB). — — with international search report (Art. 21(3)) Agent: O'BRIEN, Simon; D Young & Co LLP, 120 Hol- with born, London EC1N 2DY (GB). (74) sequence listing part of description (Rule 5.2(a)) = = = = = = = = = = = = Il 7r IN IN M 11 in ,—, IN ,—, © (54) Title: PRENYLATION ASSAY ei r .- (57) : A method for determining the activity of Rab escort protein 1 (REP1) comprising the steps: (a) providing a sample 7 1 ,1 9 comprising REP1; (b) contacting the sample of step (a) with Rab6a, Rab geranylgeranyltransferase (Rab GGTase) and a lipid donor substrate; and (c) detecting the lipidated Rab6a product.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1604146.9A GB201604146D0 (en) | 2016-03-10 | 2016-03-10 | Prenylation assay |
| PCT/GB2017/050659 WO2017153774A1 (en) | 2016-03-10 | 2017-03-10 | Prenylation assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201807766YA true SG11201807766YA (en) | 2018-10-30 |
Family
ID=55952158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201807766YA SG11201807766YA (en) | 2016-03-10 | 2017-03-10 | Prenylation assay |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20190017096A1 (en) |
| EP (2) | EP3868892A1 (en) |
| JP (1) | JP7021122B2 (en) |
| KR (2) | KR20180120751A (en) |
| CN (1) | CN109072281B (en) |
| AU (1) | AU2017230952B2 (en) |
| CA (1) | CA3016492A1 (en) |
| CY (1) | CY1124274T1 (en) |
| DK (1) | DK3426795T3 (en) |
| ES (1) | ES2862773T3 (en) |
| GB (1) | GB201604146D0 (en) |
| HK (1) | HK1258918A1 (en) |
| HR (1) | HRP20210273T1 (en) |
| HU (1) | HUE054217T2 (en) |
| LT (1) | LT3426795T (en) |
| PL (1) | PL3426795T3 (en) |
| PT (1) | PT3426795T (en) |
| RS (1) | RS62032B1 (en) |
| SG (1) | SG11201807766YA (en) |
| SI (1) | SI3426795T1 (en) |
| WO (1) | WO2017153774A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018085844A1 (en) * | 2016-11-07 | 2018-05-11 | Spark Therapeutics, Inc. | Rab escort protein potency assay |
| JP2021502820A (en) * | 2017-10-17 | 2021-02-04 | ナイトスタアールエックス リミテッド | Prenylation assay |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9803351D0 (en) | 1998-02-17 | 1998-04-15 | Oxford Biomedica Ltd | Anti-viral vectors |
| GB0009760D0 (en) | 2000-04-19 | 2000-06-07 | Oxford Biomedica Ltd | Method |
| GB201103062D0 (en) | 2011-02-22 | 2011-04-06 | Isis Innovation | Method |
| SE540689C2 (en) * | 2013-11-25 | 2018-10-09 | Esbe Ab | An valve for an indoor temperature regulating system and an air temperature conditioning unit including such a valve |
| TN2016000220A1 (en) * | 2013-12-06 | 2017-10-06 | Ct Hospitalier Universitaire Montpellier | Methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject. |
-
2016
- 2016-03-10 GB GBGB1604146.9A patent/GB201604146D0/en not_active Ceased
- 2016-03-10 US US16/080,186 patent/US20190017096A1/en not_active Abandoned
-
2017
- 2017-03-10 CA CA3016492A patent/CA3016492A1/en active Pending
- 2017-03-10 SG SG11201807766YA patent/SG11201807766YA/en unknown
- 2017-03-10 RS RS20210480A patent/RS62032B1/en unknown
- 2017-03-10 HU HUE17711290A patent/HUE054217T2/en unknown
- 2017-03-10 PT PT177112901T patent/PT3426795T/en unknown
- 2017-03-10 JP JP2018566650A patent/JP7021122B2/en active Active
- 2017-03-10 KR KR1020187029109A patent/KR20180120751A/en not_active IP Right Cessation
- 2017-03-10 CN CN201780023762.5A patent/CN109072281B/en active Active
- 2017-03-10 EP EP21152951.6A patent/EP3868892A1/en not_active Withdrawn
- 2017-03-10 LT LTEP17711290.1T patent/LT3426795T/en unknown
- 2017-03-10 PL PL17711290T patent/PL3426795T3/en unknown
- 2017-03-10 SI SI201730629T patent/SI3426795T1/en unknown
- 2017-03-10 KR KR1020237020248A patent/KR20230093528A/en not_active Application Discontinuation
- 2017-03-10 DK DK17711290.1T patent/DK3426795T3/en active
- 2017-03-10 EP EP17711290.1A patent/EP3426795B1/en active Active
- 2017-03-10 AU AU2017230952A patent/AU2017230952B2/en not_active Ceased
- 2017-03-10 ES ES17711290T patent/ES2862773T3/en active Active
- 2017-03-10 WO PCT/GB2017/050659 patent/WO2017153774A1/en active Application Filing
-
2019
- 2019-01-28 HK HK19101395.8A patent/HK1258918A1/en unknown
-
2021
- 2021-02-17 HR HRP20210273TT patent/HRP20210273T1/en unknown
- 2021-04-13 CY CY20211100321T patent/CY1124274T1/en unknown
- 2021-12-22 US US17/559,713 patent/US20220380831A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017153774A1 (en) | 2017-09-14 |
| CN109072281A (en) | 2018-12-21 |
| CN109072281B (en) | 2023-07-25 |
| KR20180120751A (en) | 2018-11-06 |
| ES2862773T3 (en) | 2021-10-07 |
| US20220380831A1 (en) | 2022-12-01 |
| PT3426795T (en) | 2021-04-07 |
| AU2017230952B2 (en) | 2022-03-10 |
| US20190017096A1 (en) | 2019-01-17 |
| GB201604146D0 (en) | 2016-04-27 |
| JP7021122B2 (en) | 2022-02-16 |
| HRP20210273T1 (en) | 2021-05-28 |
| CA3016492A1 (en) | 2017-09-14 |
| EP3868892A1 (en) | 2021-08-25 |
| KR20230093528A (en) | 2023-06-27 |
| EP3426795B1 (en) | 2021-01-27 |
| EP3426795A1 (en) | 2019-01-16 |
| JP2019509762A (en) | 2019-04-11 |
| DK3426795T3 (en) | 2021-03-01 |
| HK1258918A1 (en) | 2019-11-22 |
| CY1124274T1 (en) | 2022-07-22 |
| SI3426795T1 (en) | 2021-09-30 |
| AU2017230952A1 (en) | 2018-09-27 |
| HUE054217T2 (en) | 2021-08-30 |
| LT3426795T (en) | 2021-07-12 |
| RS62032B1 (en) | 2021-07-30 |
| PL3426795T3 (en) | 2021-12-06 |
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