SG11201807500RA - Agent for increasing intestinal butyric acid and proliferation agent for butyric acid-producing bacteria - Google Patents
Agent for increasing intestinal butyric acid and proliferation agent for butyric acid-producing bacteriaInfo
- Publication number
- SG11201807500RA SG11201807500RA SG11201807500RA SG11201807500RA SG11201807500RA SG 11201807500R A SG11201807500R A SG 11201807500RA SG 11201807500R A SG11201807500R A SG 11201807500RA SG 11201807500R A SG11201807500R A SG 11201807500RA SG 11201807500R A SG11201807500R A SG 11201807500RA
- Authority
- SG
- Singapore
- Prior art keywords
- butyric acid
- agent
- producing bacteria
- increasing intestinal
- intestinal
- Prior art date
Links
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 title abstract 26
- 230000000968 intestinal effect Effects 0.000 title abstract 10
- 239000003795 chemical substances by application Substances 0.000 title abstract 6
- 241000894006 Bacteria Species 0.000 title abstract 5
- 230000035755 proliferation Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 3
- VAWYEUIPHLMNNF-OESPXIITSA-N 1-kestose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 VAWYEUIPHLMNNF-OESPXIITSA-N 0.000 abstract 2
- GIUOHBJZYJAZNP-DVZCMHTBSA-N 1-kestose Natural products OC[C@@H]1O[C@](CO)(OC[C@]2(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)O[C@@H](O)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O GIUOHBJZYJAZNP-DVZCMHTBSA-N 0.000 abstract 2
- 206010009944 Colon cancer Diseases 0.000 abstract 2
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 2
- 208000004930 Fatty Liver Diseases 0.000 abstract 2
- 206010019708 Hepatic steatosis Diseases 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 208000008589 Obesity Diseases 0.000 abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 abstract 2
- 208000010706 fatty liver disease Diseases 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- VAWYEUIPHLMNNF-UHFFFAOYSA-N kestotriose Natural products OC1C(O)C(CO)OC1(CO)OCC1(OC2C(C(O)C(O)C(CO)O2)O)C(O)C(O)C(CO)O1 VAWYEUIPHLMNNF-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 235000020824 obesity Nutrition 0.000 abstract 2
- 230000002062 proliferating effect Effects 0.000 abstract 2
- 231100000240 steatosis hepatitis Toxicity 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/308—Foods, ingredients or supplements having a functional effect on health having an effect on cancer prevention
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/32—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/324—Foods, ingredients or supplements having a functional effect on health having an effect on the immune system
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/328—Foods, ingredients or supplements having a functional effect on health having effect on glycaemic control and diabetes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/332—Promoters of weight control and weight loss
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/28—Oligosaccharides
- A23V2250/284—Oligosaccharides, non digestible
Abstract
[Problem] To provide: an agent for increasing intestinal butyric acid which is capable of effectively increasing intestinal butyric acid; a food composition for increasing intestinal butyric acid; a proliferation agent for butyric acid-producing bacteria; a food composition for proliferating butyric acid-producing bacteria; a method for increasing intestinal butyric acid; a method for proliferating butyric acid-producing bacteria; a method for treating or preventing intestinal inflammation, fatty liver, diabetes, colorectal cancer or obesity using the same; and use of 1-kestose for producing a pharmaceutical preparation for treatment or prevention of these diseases. [Solution] An agent for increasing intestinal butyric acid and a proliferation agent for butyric acid-producing bacteria, each comprising 1-kestose as an active ingredient. According to the present invention, intestinal butyric acid in humans or animals can be easily and effectively increased with little side effects or safety concerns. According to the present invention, furthermore, intestinal inflammation, fatty liver, diabetes, colorectal cancer or obesity can be prevented or treated by increasing intestinal butyric acid in humans or animals.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2016049561 | 2016-03-14 | ||
PCT/JP2017/010066 WO2017159643A1 (en) | 2016-03-14 | 2017-03-14 | Agent for increasing intestinal butyric acid and proliferation agent for butyric acid-producing bacteria |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201807500RA true SG11201807500RA (en) | 2018-09-27 |
Family
ID=59852313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201807500RA SG11201807500RA (en) | 2016-03-14 | 2017-03-14 | Agent for increasing intestinal butyric acid and proliferation agent for butyric acid-producing bacteria |
Country Status (8)
Country | Link |
---|---|
US (1) | US20190091248A1 (en) |
EP (1) | EP3431089A4 (en) |
JP (1) | JP6275931B1 (en) |
KR (1) | KR20180122379A (en) |
CN (1) | CN109069522A (en) |
PH (1) | PH12018501988A1 (en) |
SG (1) | SG11201807500RA (en) |
WO (1) | WO2017159643A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108064132A (en) | 2014-10-31 | 2018-05-22 | 霍勒拜欧姆公司 | The method and composition related with the antimicrobial treatments of illness and diagnosis |
CA3073838A1 (en) | 2017-08-30 | 2019-03-07 | Pendulum Therapeutics, Inc. | Methods and compositions for treatment of microbiome-associated disorders |
JP7235270B2 (en) * | 2018-02-09 | 2023-03-08 | エースバイオプロダクト株式会社 | Blood sugar elevation inhibitor and method for producing same |
EP3823651A4 (en) * | 2018-07-19 | 2022-04-27 | Pendulum Therapeutics, Inc. | Methods and compositions for microbial engraftment |
JP7216260B2 (en) * | 2018-11-06 | 2023-02-01 | 株式会社明治 | Composition for promoting growth of Coprococcus spp. |
JP6842072B2 (en) * | 2019-03-07 | 2021-03-17 | 物産フードサイエンス株式会社 | Eggerthella bacteria count suppressant |
KR102128287B1 (en) * | 2019-08-23 | 2020-06-30 | 주식회사 엔테로바이옴 | NEW Akkermansia muciniphila EB-AMDK19 strain AND uses thereof |
KR102128289B1 (en) * | 2019-08-23 | 2020-06-30 | 주식회사 엔테로바이옴 | NEW Akkermansia muciniphila EB-AMDK27 strain AND uses thereof |
JP2021115000A (en) | 2020-01-27 | 2021-08-10 | 物産フードサイエンス株式会社 | Method of manufacturing solid sugar containing 1-kestose, and solid sugar |
CN111820419B (en) * | 2020-07-24 | 2022-05-27 | 中国海洋大学 | Composition for targeted regulation and control of enteron-bacterium and short-chain fatty acid producing bacterium |
CN111996267A (en) * | 2020-08-11 | 2020-11-27 | 康美华大基因技术有限公司 | Fluorescent quantitative PCR (polymerase chain reaction) primer group and kit for rapidly detecting AKK (alkyl ketene dimer) bacteria and application of fluorescent quantitative PCR primer group and kit |
KR20220097324A (en) * | 2020-12-31 | 2022-07-07 | 주식회사 삼양사 | Growth suppression of gut microbiome using kestose |
CN113461751A (en) * | 2021-07-15 | 2021-10-01 | 量子高科(广东)生物有限公司 | Fructooligosaccharide with high kestose content and application thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004049093A (en) * | 2002-07-18 | 2004-02-19 | Meiji Milk Prod Co Ltd | Food composition and medicine for increasing intestinal butyric acid |
US20050118299A1 (en) * | 2003-12-01 | 2005-06-02 | The Iams Company | Companion animal compositions comprising short chain oligofructose |
JP2005247752A (en) * | 2004-03-04 | 2005-09-15 | Hokuren Federation Of Agricult Coop:The | Blood cholesterol rise inhibitor |
JP4669235B2 (en) * | 2004-04-21 | 2011-04-13 | ホクレン農業協同組合連合会 | Bifidobacteria growth agent in intestinal environment |
JP4162147B2 (en) * | 2005-04-21 | 2008-10-08 | ホクレン農業協同組合連合会 | Allergy suppressant |
CA2628035A1 (en) * | 2005-10-13 | 2007-04-19 | Meiji Seika Kaisha, Ltd. | Composition for improving intestinal microflora |
JP5921894B2 (en) * | 2012-01-20 | 2016-05-24 | アサヒカルピスウェルネス株式会社 | Intestinal butyric acid producing bacteria increasing agent |
-
2017
- 2017-03-14 CN CN201780017017.XA patent/CN109069522A/en active Pending
- 2017-03-14 US US16/084,310 patent/US20190091248A1/en not_active Abandoned
- 2017-03-14 EP EP17766642.7A patent/EP3431089A4/en not_active Withdrawn
- 2017-03-14 JP JP2017549362A patent/JP6275931B1/en active Active
- 2017-03-14 SG SG11201807500RA patent/SG11201807500RA/en unknown
- 2017-03-14 WO PCT/JP2017/010066 patent/WO2017159643A1/en active Application Filing
- 2017-03-14 KR KR1020187028400A patent/KR20180122379A/en not_active IP Right Cessation
-
2018
- 2018-09-14 PH PH12018501988A patent/PH12018501988A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP3431089A4 (en) | 2020-04-15 |
JPWO2017159643A1 (en) | 2018-03-22 |
US20190091248A1 (en) | 2019-03-28 |
CN109069522A (en) | 2018-12-21 |
EP3431089A1 (en) | 2019-01-23 |
WO2017159643A1 (en) | 2017-09-21 |
KR20180122379A (en) | 2018-11-12 |
PH12018501988A1 (en) | 2019-06-24 |
JP6275931B1 (en) | 2018-02-07 |
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