SG11201806620TA - Compositions and methods for treating infections - Google Patents

Compositions and methods for treating infections

Info

Publication number
SG11201806620TA
SG11201806620TA SG11201806620TA SG11201806620TA SG11201806620TA SG 11201806620T A SG11201806620T A SG 11201806620TA SG 11201806620T A SG11201806620T A SG 11201806620TA SG 11201806620T A SG11201806620T A SG 11201806620TA SG 11201806620T A SG11201806620T A SG 11201806620TA
Authority
SG
Singapore
Prior art keywords
international
co7d
pct
new york
methods
Prior art date
Application number
SG11201806620TA
Other languages
English (en)
Inventor
Stephen Thomas
Allen Hopper
Mathew Welsch
Original Assignee
Vyera Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vyera Pharmaceuticals Llc filed Critical Vyera Pharmaceuticals Llc
Publication of SG11201806620TA publication Critical patent/SG11201806620TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50Three nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201806620TA 2016-02-05 2017-02-02 Compositions and methods for treating infections SG11201806620TA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662291900P 2016-02-05 2016-02-05
US201662375712P 2016-08-16 2016-08-16
PCT/US2017/016224 WO2017136556A1 (fr) 2016-02-05 2017-02-02 Compositions et méthodes de traitement d'infections bactériennes

Publications (1)

Publication Number Publication Date
SG11201806620TA true SG11201806620TA (en) 2018-09-27

Family

ID=59500993

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201806620TA SG11201806620TA (en) 2016-02-05 2017-02-02 Compositions and methods for treating infections
SG10202007239QA SG10202007239QA (en) 2016-02-05 2017-02-02 Compositions and methods for treating infections

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10202007239QA SG10202007239QA (en) 2016-02-05 2017-02-02 Compositions and methods for treating infections

Country Status (17)

Country Link
US (2) US10774073B2 (fr)
EP (1) EP3411367A4 (fr)
JP (1) JP6949055B2 (fr)
KR (1) KR20180119590A (fr)
CN (1) CN109071486A (fr)
AU (2) AU2017213824B9 (fr)
BR (1) BR112018015924A2 (fr)
CA (1) CA3013760A1 (fr)
CL (1) CL2018002074A1 (fr)
CU (1) CU20180083A7 (fr)
EA (1) EA201891766A1 (fr)
IL (2) IL260952B (fr)
MX (1) MX2018009504A (fr)
PH (1) PH12018501646A1 (fr)
SG (2) SG11201806620TA (fr)
TW (1) TW201731836A (fr)
WO (1) WO2017136556A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6949055B2 (ja) 2016-02-05 2021-10-13 ヴェラ ファーマシューティカルズ,エルエルシー 感染症を治療するための組成物および方法
AU2018312985A1 (en) * 2017-08-07 2020-02-27 Vyera Pharmaceuticals, LLC DHFR inhibitors, compositions, and methods related thereto
EP3795684A4 (fr) 2018-04-26 2022-01-05 Guangzhou Cas Lamvac Biotech Co., Ltd. Système d'atténuation et utilisation associée
JP2023539463A (ja) 2020-08-17 2023-09-14 アリゴス セラピューティクス インコーポレイテッド Pd-l1を標的とするための方法及び組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4532240A (en) 1982-09-09 1985-07-30 Warner-Lambert Company Diaminopyrimidines
CA1244028A (fr) 1983-04-14 1988-11-01 Hans Maag Derives de pyrimidine
AU4690999A (en) * 1998-08-13 2000-03-06 Warner-Lambert Company Diaminopyrimidines and combination therapies effective for treatment of p-glycoprotein positive cancers
US20040006042A1 (en) * 1998-08-13 2004-01-08 Berry David Allen Diaminopyrimidines and combination therapies effective for treatment of P-glycoprotein positive cancers
JP6949055B2 (ja) * 2016-02-05 2021-10-13 ヴェラ ファーマシューティカルズ,エルエルシー 感染症を治療するための組成物および方法
AU2018312985A1 (en) 2017-08-07 2020-02-27 Vyera Pharmaceuticals, LLC DHFR inhibitors, compositions, and methods related thereto

Also Published As

Publication number Publication date
BR112018015924A2 (pt) 2018-12-26
SG10202007239QA (en) 2020-09-29
WO2017136556A1 (fr) 2017-08-10
CU20180083A7 (es) 2019-03-04
CN109071486A (zh) 2018-12-21
TW201731836A (zh) 2017-09-16
AU2017213824B9 (en) 2021-11-25
EP3411367A4 (fr) 2019-07-10
EP3411367A1 (fr) 2018-12-12
KR20180119590A (ko) 2018-11-02
MX2018009504A (es) 2019-05-06
US10774073B2 (en) 2020-09-15
IL291266A (en) 2022-05-01
CL2018002074A1 (es) 2019-02-01
IL260952B (en) 2022-04-01
AU2017213824B2 (en) 2021-11-18
JP6949055B2 (ja) 2021-10-13
EA201891766A1 (ru) 2019-02-28
AU2022200967A1 (en) 2022-03-03
US20190077794A1 (en) 2019-03-14
US11530198B2 (en) 2022-12-20
PH12018501646A1 (en) 2019-05-27
CA3013760A1 (fr) 2017-08-10
AU2017213824A1 (en) 2018-09-06
JP2019504889A (ja) 2019-02-21
US20200407345A1 (en) 2020-12-31

Similar Documents

Publication Publication Date Title
SG11201900163PA (en) Macrocycle kinase inhibitors
SG11201906883SA (en) Methods for the administration of certain vmat2 inhibitors
SG11201805300QA (en) Heterocyclic compounds as immunomodulators
SG11201808990QA (en) Compositions for topical application of compounds
SG11201407580YA (en) Composition comprising two antibodies engineered to have reduced and increased effector function
SG11201805044WA (en) Compounds useful as kinase inhibitors
SG11201805645QA (en) Lsd1 inhibitors
SG11201811564QA (en) Methods of treating ovarian cancer
SG11201906386XA (en) Combination therapy involving diaryl macrocyclic compounds
SG11201810927QA (en) Pd-l1-specific antibodies and methods of using the same
SG11201808222RA (en) Methods of treatment of cholestatic diseases
SG11201900405XA (en) Compounds, compositions and methods for treating or preventing a sympton associated with gout or hyperuricemia
SG11201805001UA (en) Method of treating influenza a
SG11201907356SA (en) Piperidine-substituted mnk inhibitors and methods related thereto
SG11201900551WA (en) Spiro-lactam nmda receptor modulators and uses thereof
SG11201900558RA (en) Spiro-lactam nmda receptor modulators and uses thereof
SG11201900546UA (en) Spiro-lactam and bis-spiro-lactam nmda receptor modulators and uses thereof
SG11201903061YA (en) Combination treatments comprising administration of imidazopyrazinones
SG11201806620TA (en) Compositions and methods for treating infections
SG11201809882XA (en) Pharmaceutical combinations for treating cancer
SG11201909501TA (en) Personalized 3d neural culture system for generating human oligodendrocytes and studying myelination in vitro
SG11201408171SA (en) Fbxo3 inhibitors
SG11201903012RA (en) Anti-c1s antibodies and methods of use thereof
SG11201805755SA (en) Methods of administering hepcidin
SG11201900123TA (en) Compositions and methods for treating frontotemporal dementia