SG11201805527QA - Composition for reducing the frequency of urination, method of making and use thereof - Google Patents
Composition for reducing the frequency of urination, method of making and use thereofInfo
- Publication number
- SG11201805527QA SG11201805527QA SG11201805527QA SG11201805527QA SG11201805527QA SG 11201805527Q A SG11201805527Q A SG 11201805527QA SG 11201805527Q A SG11201805527Q A SG 11201805527QA SG 11201805527Q A SG11201805527Q A SG 11201805527QA SG 11201805527Q A SG11201805527Q A SG 11201805527QA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- pct
- urination
- frequency
- reducing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization IIIMIOH0110101011111 HO 11111 0101111110111110111110011111110111011# International Bureau ... ...... (10) International Publication Number (43) International Publication Date ..... .....\" WO 2017/058436 Al 6 April 2017 (06.04.2017) WIPO I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 31/19 (2006.01) A61P 7/12 (2006.01) kind A61K 31/192 (2006.01) A61P 7/00 (2006.01) AO, BZ, of national protection available): AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, (21) International Application Number: DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, PCT/US2016/049246 HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, (22) International Filing Date: KZ, 29 August 2016 (29.08.2016) MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, (25) Filing Language: English SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (26) Publication Language: English TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: (84) Designated States (unless otherwise indicated, for every 14/870,676 30 September 2015 (30.09.2015) US kind GM, of regional protection available): ARIPO (BW, GH, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, (71) Applicant: WELLESLEY PHARMACEUTICALS, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (72) LLC [US/US]; 3 Valley View Drive, Newtown, PA 18940 TJ, (US). DK, LV, Inventor: DILL, David, A.; 3 Valley View Drive, New TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, town, PA 18940 (US). TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (74) Agent: WANG, Ping, M. D.; Andrews Kurth, LLP, 1350 I Street, N.W. Suite 1100, Washington, DC 20005 (US). Published: — with international search report (Art. 21(3)) (54) Title: COMPOSITION FOR REDUCING THE FREQUENCY OF URINATION, METHOD OF MAKING AND USE THEREOF (57) : A method for manufacturing a pharmaceutical composition for reducing the frequency of urination is dis - NSA! D alone closed. The pharmaceutical composition comprises (1) an an- algesic agent and (2) an a-blocker, a 5a-reductase inhibitor or 0 3 -ci-t- both. 111 z 3 --o--atwetaminophoo 4, ,n m 17 -' ° a) ..c 250 - V ;,.., —E.—Aspirin t JIB thoproten 8 - no - 5 0 ,.. kJ 4- d I 8 ---*-- aproun i CD ° .tt U O .-- 100 - u ° 4 .., ,..) — e - .4 V; en Dose of NSAID 71' 15000-0.00005 ii,M) Ot kr) 0 IN ,-, © ei FIG. l'A O
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/870,676 US10596127B2 (en) | 2013-03-14 | 2015-09-30 | Composition for reducing the frequency of urination, method of making and use thereof |
PCT/US2016/049246 WO2017058436A1 (en) | 2015-09-30 | 2016-08-29 | Composition for reducing the frequency of urination, method of making and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201805527QA true SG11201805527QA (en) | 2018-07-30 |
Family
ID=58424324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201805527QA SG11201805527QA (en) | 2015-09-30 | 2016-08-29 | Composition for reducing the frequency of urination, method of making and use thereof |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP3355877A4 (en) |
JP (1) | JP2018529710A (en) |
KR (1) | KR20180066113A (en) |
CN (1) | CN108430465A (en) |
AU (1) | AU2016331879A1 (en) |
SG (1) | SG11201805527QA (en) |
WO (1) | WO2017058436A1 (en) |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5395626A (en) * | 1994-03-23 | 1995-03-07 | Ortho Pharmaceutical Corporation | Multilayered controlled release pharmaceutical dosage form |
KR100630290B1 (en) * | 1998-05-15 | 2006-09-29 | 쥬가이 세이야쿠 가부시키가이샤 | Regulated release preparations |
US20030194428A1 (en) * | 2002-04-10 | 2003-10-16 | Miller Frederick H. | Process for encapsulating multi-phase, multi-compartment capsules |
EP1501517B1 (en) * | 2002-04-24 | 2007-05-02 | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG | Pharmaceutical combination for the treatment of benign prostatic hyperplasia or for the long-term prevention of acute urinary retention |
CA2658170A1 (en) * | 2006-07-11 | 2008-01-17 | Mutual Pharmaceutical Company, Inc. | Controlled-release formulations |
KR101479324B1 (en) * | 2006-11-09 | 2015-01-05 | 오렉시젠 세러퓨틱스 인크. | Layered pharmaceutical formulations comprising an intermediate rapidly dissolving layer |
US9119878B2 (en) * | 2010-07-08 | 2015-09-01 | Wellesley Pharmaceuticals, Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
CN103191430A (en) * | 2012-01-04 | 2013-07-10 | 韦尔斯利医药有限公司 | Sustained release preparation for relieving frequent micturition and application method thereof |
CN103191429A (en) * | 2012-01-04 | 2013-07-10 | 韦尔斯利医药有限公司 | Extended release formulation for relieving frequent micturition and application method thereof |
AU2012363789B2 (en) * | 2012-01-04 | 2017-04-13 | Wellesley Pharmaceuticals, Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
MX2014011128A (en) * | 2012-03-19 | 2015-08-10 | Wellesley Pharmaceuticals Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof. |
MY171526A (en) * | 2012-07-27 | 2019-10-16 | Wellesley Pharmaceuticals Llc | Pharmaceutical formulation for reducing frequency of urination and method of use thereof |
TW201422254A (en) * | 2012-11-21 | 2014-06-16 | Ferring Bv | Composition for immediate and extended release |
BR102013020508B1 (en) * | 2013-08-12 | 2021-01-12 | Ems S/A. | DOSAGE FORM THAT UNDERSTANDS A 5-ALPHA REDUCTASE STEROID INHIBITOR AND AN ALPHA BLOCKER, PROCESS FOR THE PREPARATION OF A DOSAGE FORM AND USE OF THE DOSAGE FORM |
-
2016
- 2016-08-29 CN CN201680069818.6A patent/CN108430465A/en active Pending
- 2016-08-29 AU AU2016331879A patent/AU2016331879A1/en not_active Abandoned
- 2016-08-29 WO PCT/US2016/049246 patent/WO2017058436A1/en active Application Filing
- 2016-08-29 JP JP2018516063A patent/JP2018529710A/en active Pending
- 2016-08-29 EP EP16852276.1A patent/EP3355877A4/en not_active Withdrawn
- 2016-08-29 SG SG11201805527QA patent/SG11201805527QA/en unknown
- 2016-08-29 KR KR1020187011990A patent/KR20180066113A/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20180066113A (en) | 2018-06-18 |
WO2017058436A1 (en) | 2017-04-06 |
CN108430465A (en) | 2018-08-21 |
EP3355877A4 (en) | 2019-05-15 |
EP3355877A1 (en) | 2018-08-08 |
AU2016331879A1 (en) | 2018-05-17 |
JP2018529710A (en) | 2018-10-11 |
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