SG11201805381TA - Electroporation device with detachable needle array with lock-out system - Google Patents

Electroporation device with detachable needle array with lock-out system

Info

Publication number
SG11201805381TA
SG11201805381TA SG11201805381TA SG11201805381TA SG11201805381TA SG 11201805381T A SG11201805381T A SG 11201805381TA SG 11201805381T A SG11201805381T A SG 11201805381TA SG 11201805381T A SG11201805381T A SG 11201805381TA SG 11201805381T A SG11201805381T A SG 11201805381TA
Authority
SG
Singapore
Prior art keywords
suite
international
inovio
pike
germantown
Prior art date
Application number
SG11201805381TA
Other languages
English (en)
Inventor
Beat Stadelmann
Stephen Kemmerrer
Alejandro Campillo-Agusti
Eduardo Ho
Nathan Lovell
Steven Masterson
Original Assignee
Inovio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inovio Pharmaceuticals Inc filed Critical Inovio Pharmaceuticals Inc
Publication of SG11201805381TA publication Critical patent/SG11201805381TA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A61N1/0424—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00172—Connectors and adapters therefor
    • A61B2018/00178—Electrical connectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00184—Moving parts
    • A61B2018/00196—Moving parts reciprocating lengthwise
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00613—Irreversible electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A61B2018/143—Needle multiple needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1475—Electrodes retractable in or deployable from a housing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Pathology (AREA)
  • Vascular Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Prostheses (AREA)
SG11201805381TA 2015-12-30 2016-12-30 Electroporation device with detachable needle array with lock-out system SG11201805381TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562272758P 2015-12-30 2015-12-30
PCT/US2016/069438 WO2017117508A1 (en) 2015-12-30 2016-12-30 Electroporation device with detachable needle array with lock-out system

Publications (1)

Publication Number Publication Date
SG11201805381TA true SG11201805381TA (en) 2018-08-30

Family

ID=59225790

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202110370PA SG10202110370PA (en) 2015-12-30 2016-12-30 Electroporation device with detachable needle array with lock-out system
SG11201805381TA SG11201805381TA (en) 2015-12-30 2016-12-30 Electroporation device with detachable needle array with lock-out system

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10202110370PA SG10202110370PA (en) 2015-12-30 2016-12-30 Electroporation device with detachable needle array with lock-out system

Country Status (17)

Country Link
US (3) US11071859B2 (ko)
EP (3) EP4311568A3 (ko)
JP (3) JP6961598B2 (ko)
KR (1) KR20180099751A (ko)
CN (2) CN109414580B (ko)
AU (2) AU2016381186B2 (ko)
CA (2) CA3200544A1 (ko)
ES (2) ES2843400T3 (ko)
IL (2) IL300102A (ko)
LT (1) LT3397337T (ko)
MX (2) MX2018008007A (ko)
PE (1) PE20181501A1 (ko)
PL (1) PL3397337T3 (ko)
PT (1) PT3397337T (ko)
RU (1) RU2746466C2 (ko)
SG (2) SG10202110370PA (ko)
WO (1) WO2017117508A1 (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4311568A3 (en) 2015-12-30 2024-03-20 Inovio Pharmaceuticals, Inc. Electroporation device with detachable needle array with lock-out system
SE541651C2 (en) 2017-07-28 2019-11-19 Scandinavian Chemotech Ab An electrode device and a needle electrode for use in delivery of electrical pulses to a desired tissue of a mammal
US11590345B2 (en) 2017-08-08 2023-02-28 Pulse Biosciences, Inc. Treatment of tissue by the application of energy
US10850095B2 (en) 2017-08-08 2020-12-01 Pulse Biosciences, Inc. Treatment of tissue by the application of energy
US10857347B2 (en) 2017-09-19 2020-12-08 Pulse Biosciences, Inc. Treatment instrument and high-voltage connectors for robotic surgical system
WO2020077019A1 (en) * 2018-10-10 2020-04-16 Pulse Biosciences, Inc. Treatment of dermal glands by the application of non-thermal energy
US11571569B2 (en) 2019-02-15 2023-02-07 Pulse Biosciences, Inc. High-voltage catheters for sub-microsecond pulsing
JP2022554401A (ja) * 2019-11-11 2022-12-28 プレシゲン，インコーポレイテッド エレクトロポレーション（ｅｌｅｃｔｒｏｐｏｒａｔｉｏｎ）装置および方法
WO2022214664A1 (en) 2021-04-09 2022-10-13 Philogen S.P.A. Improved interferon-gamma mutant
USD977094S1 (en) * 2021-04-23 2023-01-31 Pacira Cryotech, Inc. Tip assembly for a cryogenic device
WO2024023246A1 (en) 2022-07-28 2024-02-01 Philogen S.P.A. Antibody binding to pd1
WO2024033362A1 (en) 2022-08-08 2024-02-15 Atb Therapeutics Humanized antibodies against cd79b

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2045691C (en) * 1989-02-01 2005-09-27 Richard C. Sircom Disposable automatic hypodermic needle guard
US5320610A (en) * 1991-12-16 1994-06-14 Inbae Yoon Automatic retractable trocar with safety shield and method of use
US5360408A (en) * 1992-11-16 1994-11-01 Vaillancourt Vincent L Shielded hypodermic needle assembly and a shield assembly for a hypodermic needle
US5702359A (en) * 1995-06-06 1997-12-30 Genetronics, Inc. Needle electrodes for mediated delivery of drugs and genes
US5439440A (en) * 1993-04-01 1995-08-08 Genetronics, Inc. Electroporation system with voltage control feedback for clinical applications
US6055453A (en) 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
US6569123B2 (en) * 1999-10-14 2003-05-27 Becton, Dickinson And Company Prefillable intradermal injector
US6972002B2 (en) * 2000-04-28 2005-12-06 Specialized Health Products, Inc. Passively activated safety shield for a catheter insertion needle
EP1385560B1 (en) 2001-04-13 2018-05-16 Becton, Dickinson and Company Prefillable intradermal delivery device with hidden needle and passive shielding
US20040204669A1 (en) * 2001-07-05 2004-10-14 Hofmann Gunter A. Apparatus for electroporation mediated delivery for drugs and genes
CA2477872A1 (en) 2002-03-07 2003-09-18 Merck & Co., Inc. Clinical syringe with electrical stimulation aspects
AU2003201336A1 (en) * 2002-03-19 2003-10-16 Becton, Dickinson And Company Needle assembly
US6912417B1 (en) * 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
WO2003089043A2 (en) * 2002-04-19 2003-10-30 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
US20050070841A1 (en) * 2002-07-04 2005-03-31 Inovio As Electroporation device and injection apparatus
US7500963B2 (en) * 2003-07-22 2009-03-10 Safety Syringes, Inc. Systems and methods for automatic medical injection with safeguard
US20080058706A1 (en) * 2004-06-30 2008-03-06 Genetronics, Inc. Modular electroporation device with disposable electrode and drug delivery components
US20060036210A1 (en) * 2004-06-30 2006-02-16 Lei Zhang Modular electroporation device with disposable electrode and drug delivery components
WO2006084173A1 (en) * 2005-02-04 2006-08-10 The Johns Hopkins University Electroporation gene therapy gun system
CA2950817C (en) * 2006-06-30 2018-07-24 Abbvie Biotechnology Ltd. Automatic injection device
EP2152358B1 (en) * 2007-04-27 2011-03-02 Echo Therapeutics, Inc. Skin permeation device for analyte sensing or transdermal drug delivery
US8361066B2 (en) 2009-01-12 2013-01-29 Ethicon Endo-Surgery, Inc. Electrical ablation devices
GB0914981D0 (en) * 2009-08-28 2009-09-30 Micromode Medical Ltd Electrostimulation device
AU2011223753B2 (en) 2010-03-01 2014-06-26 Inovio Pharmaceuticals, Inc. A tolerable and minimally invasive skin electroporation device
CN102892461B (zh) * 2010-04-28 2015-11-25 因诺维奥制药公司 口部粘膜电穿孔装置及其用途
KR101066883B1 (ko) 2010-07-01 2011-09-26 최종수 전류 인가형 멀티 주사 바늘 및 자동주사장치
US9289606B2 (en) 2010-09-02 2016-03-22 St. Jude Medical, Atrial Fibrillation Division, Inc. System for electroporation therapy
US20120101475A1 (en) * 2010-10-21 2012-04-26 Meridian Medical Technologies, Inc. High Efficiency Auto-Injector
EP2489384A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
KR102171142B1 (ko) * 2011-06-28 2020-10-28 이노비오 파마수티컬즈, 인크. 최소 침습 피부 전기천공 장치
WO2013166203A2 (en) * 2012-05-01 2013-11-07 Life Technologies Corporation Pippette devices, systems, and methods of use thereof
WO2014066655A2 (en) * 2012-10-25 2014-05-01 Oncosec Medical Incorporation Electroporation device
WO2015089492A2 (en) 2013-12-13 2015-06-18 The Trustees Of The University Of Pennsylvania Dna antibody constructs and method of using same
EP4311568A3 (en) 2015-12-30 2024-03-20 Inovio Pharmaceuticals, Inc. Electroporation device with detachable needle array with lock-out system

Also Published As

Publication number Publication date
PT3397337T (pt) 2020-11-24
CN109414580A (zh) 2019-03-01
RU2018127656A3 (ko) 2020-05-14
EP3397337B1 (en) 2020-07-29
CA3200544A1 (en) 2017-07-06
US20210330967A1 (en) 2021-10-28
MX2018008007A (es) 2019-03-28
ES2970438T3 (es) 2024-05-28
BR112018013312A2 (pt) 2018-12-11
JP6961598B2 (ja) 2021-11-05
US20190009084A1 (en) 2019-01-10
US11883653B2 (en) 2024-01-30
CN109414580B (zh) 2022-09-20
ES2843400T3 (es) 2021-07-16
IL260072A (en) 2018-07-31
AU2022202620B2 (en) 2024-05-02
CN115475000A (zh) 2022-12-16
WO2017117508A1 (en) 2017-07-06
EP3397337A1 (en) 2018-11-07
MX2022009539A (es) 2022-09-09
RU2018127656A (ru) 2020-01-30
AU2016381186A1 (en) 2018-07-12
AU2016381186B2 (en) 2022-01-20
PE20181501A1 (es) 2018-09-18
JP7365383B2 (ja) 2023-10-19
LT3397337T (lt) 2020-11-25
EP4311568A2 (en) 2024-01-31
JP2022002758A (ja) 2022-01-11
EP3799922A1 (en) 2021-04-07
RU2746466C2 (ru) 2021-04-14
JP2019500158A (ja) 2019-01-10
SG10202110370PA (en) 2021-11-29
IL260072B2 (en) 2023-06-01
EP3799922B1 (en) 2023-08-30
PL3397337T3 (pl) 2021-01-25
AU2022202620A1 (en) 2022-05-12
EP3397337A4 (en) 2019-01-02
US20230398350A1 (en) 2023-12-14
IL300102A (en) 2023-03-01
KR20180099751A (ko) 2018-09-05
RU2021109844A3 (ko) 2021-10-07
US11071859B2 (en) 2021-07-27
RU2021109844A (ru) 2021-05-13
CA3009348A1 (en) 2017-07-06
JP2023168619A (ja) 2023-11-24
EP4311568A3 (en) 2024-03-20

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