SG11201706562QA - NON-MEMBRANE DISRUPTIVE p53 ACTIVATING STAPLED PEPTIDES - Google Patents
NON-MEMBRANE DISRUPTIVE p53 ACTIVATING STAPLED PEPTIDESInfo
- Publication number
- SG11201706562QA SG11201706562QA SG11201706562QA SG11201706562QA SG11201706562QA SG 11201706562Q A SG11201706562Q A SG 11201706562QA SG 11201706562Q A SG11201706562Q A SG 11201706562QA SG 11201706562Q A SG11201706562Q A SG 11201706562QA SG 11201706562Q A SG11201706562Q A SG 11201706562QA
- Authority
- SG
- Singapore
- Prior art keywords
- activating
- stapled peptides
- membrane disruptive
- disruptive
- membrane
- Prior art date
Links
- 230000003213 activating effect Effects 0.000 title 1
- 239000012528 membrane Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10201501119W | 2015-02-13 | ||
| PCT/SG2016/050079 WO2016130092A1 (en) | 2015-02-13 | 2016-02-15 | Non-membrane disruptive p53 activating stapled peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201706562QA true SG11201706562QA (en) | 2017-09-28 |
Family
ID=56614951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201706562QA SG11201706562QA (en) | 2015-02-13 | 2016-02-15 | NON-MEMBRANE DISRUPTIVE p53 ACTIVATING STAPLED PEPTIDES |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11319344B2 (enrdf_load_stackoverflow) |
| EP (1) | EP3256484B1 (enrdf_load_stackoverflow) |
| JP (1) | JP7028643B2 (enrdf_load_stackoverflow) |
| CN (1) | CN107531759B (enrdf_load_stackoverflow) |
| SG (1) | SG11201706562QA (enrdf_load_stackoverflow) |
| WO (1) | WO2016130092A1 (enrdf_load_stackoverflow) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020027585A2 (ko) * | 2018-07-31 | 2020-02-06 | 주식회사 레모넥스 | 폴리펩타이드 전달용 조성물 |
| KR102388028B1 (ko) * | 2018-07-31 | 2022-04-20 | 주식회사 레모넥스 | 폴리펩타이드 전달용 조성물 |
| US20230174579A1 (en) * | 2019-12-05 | 2023-06-08 | Ajou University Industry-Academic Cooperation Foundation | Pharmaceutical composition for preventing or treating behcet's disease and rheumatoid arthritis, containing peptide or mixture thereof as active ingredient |
| CN111613275B (zh) * | 2020-05-26 | 2021-03-16 | 中国海洋大学 | 一种基于rmsd多特征的药物分子动力学结果分析方法 |
| US20230330238A1 (en) | 2020-10-14 | 2023-10-19 | Dana-Farber Cancer Institute, Inc. | Chimeric conjugates for degradation of viral and host proteins and methods of use |
| WO2024051616A1 (zh) * | 2022-09-09 | 2024-03-14 | 湖南大学 | 一种多肽及其制备方法和用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8343760B2 (en) | 2008-06-05 | 2013-01-01 | University Of Maryland, Baltimore | p53 activator peptides |
| AR077879A1 (es) * | 2009-08-17 | 2011-09-28 | Roche Glycart Ag | Inmunoconjugados dirigidos |
| US20120328692A1 (en) | 2011-06-24 | 2012-12-27 | University Of Maryland, Baltimore | Potent d-peptide antagonists of mdm2 and mdmx for anticancer therapy |
| US20150246946A1 (en) * | 2012-10-01 | 2015-09-03 | Agency For Science, Technology And Research | Peptides and methods for treating cancer |
| HK1222555A1 (zh) | 2013-03-13 | 2017-07-07 | President And Fellows Of Harvard College | 钉合且缝合的多肽及其用途 |
| US20150010932A1 (en) * | 2013-07-02 | 2015-01-08 | Salk Institute For Biological Studies | Methods for assaying protein-protein interactions |
-
2016
- 2016-02-15 WO PCT/SG2016/050079 patent/WO2016130092A1/en active Application Filing
- 2016-02-15 EP EP16749553.0A patent/EP3256484B1/en active Active
- 2016-02-15 US US15/550,766 patent/US11319344B2/en active Active
- 2016-02-15 CN CN201680021720.3A patent/CN107531759B/zh active Active
- 2016-02-15 JP JP2017542470A patent/JP7028643B2/ja active Active
- 2016-02-15 SG SG11201706562QA patent/SG11201706562QA/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US11319344B2 (en) | 2022-05-03 |
| US20180030090A1 (en) | 2018-02-01 |
| JP2018507689A (ja) | 2018-03-22 |
| CN107531759B (zh) | 2021-11-16 |
| EP3256484A1 (en) | 2017-12-20 |
| CN107531759A (zh) | 2018-01-02 |
| EP3256484A4 (en) | 2018-07-25 |
| WO2016130092A1 (en) | 2016-08-18 |
| EP3256484B1 (en) | 2021-06-23 |
| JP7028643B2 (ja) | 2022-03-02 |
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