SG11201706353WA - Compounds as well as separation method, synthetic method and use thereof - Google Patents
Compounds as well as separation method, synthetic method and use thereofInfo
- Publication number
- SG11201706353WA SG11201706353WA SG11201706353WA SG11201706353WA SG11201706353WA SG 11201706353W A SG11201706353W A SG 11201706353WA SG 11201706353W A SG11201706353W A SG 11201706353WA SG 11201706353W A SG11201706353W A SG 11201706353WA SG 11201706353W A SG11201706353W A SG 11201706353WA
- Authority
- SG
- Singapore
- Prior art keywords
- compounds
- well
- synthetic method
- separation method
- separation
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 238000000926 separation method Methods 0.000 title 1
- 238000010189 synthetic method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/12—Preparation of carboxylic acid esters from asymmetrical anhydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/56—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/58—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/62—Use of additives, e.g. for stabilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510058282.5A CN105985244A (en) | 2015-02-04 | 2015-02-04 | Compound as well as separation method, synthetic method and application thereof |
| PCT/CN2016/072306 WO2016124087A1 (en) | 2015-02-04 | 2016-01-27 | Compound, and separation method, synthesis method and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201706353WA true SG11201706353WA (en) | 2017-09-28 |
Family
ID=56563438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201706353WA SG11201706353WA (en) | 2015-02-04 | 2016-01-27 | Compounds as well as separation method, synthetic method and use thereof |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10099998B2 (en) |
| EP (1) | EP3255031B1 (en) |
| JP (1) | JP6686032B2 (en) |
| KR (1) | KR102160471B1 (en) |
| CN (2) | CN105985244A (en) |
| AU (1) | AU2016214849B2 (en) |
| MY (1) | MY188671A (en) |
| SG (1) | SG11201706353WA (en) |
| WO (1) | WO2016124087A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104024270B (en) | 2011-12-26 | 2016-07-06 | 北京北大维信生物科技有限公司 | A kind of sterol derivative, Preparation Method And The Use |
| CN112964812A (en) * | 2021-02-05 | 2021-06-15 | 山东省产品质量检验研究院 | Method for detecting 8 sweetening agents in dairy product |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5559140A (en) * | 1978-10-30 | 1980-05-02 | Sankyo Co Ltd | 3,5-dihydroxypentanoic alkyl ester derivative, its preparation and remedy for hyperlipemia containing the same as the effective component |
| JPS56154439A (en) * | 1980-04-30 | 1981-11-30 | Sankyo Co Ltd | Ml-236c derivative |
| JPS59137443A (en) * | 1983-01-27 | 1984-08-07 | Akira Endo | Metal salt and alkyl ester of dihydromonacolin l carboxylic acid and its preparation |
| US4997849A (en) * | 1989-06-23 | 1991-03-05 | Merck & Co., Inc. | Microbial transformation of simvastatin |
| SI20072A (en) * | 1998-09-18 | 2000-04-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | PROCEDURE OF PREPARATION OF INHIBITORS OF HMG-CoA REDUCTASE |
| US7141602B2 (en) | 1998-09-18 | 2006-11-28 | Lek Pharmaceuticals D.D. | Process for obtaining HMG-CoA reductase inhibitors of high purity |
| CN102617533B (en) * | 2011-02-01 | 2014-08-27 | 北京北大维信生物科技有限公司 | Compound separated from red yeast rice, its preparation method and application |
-
2015
- 2015-02-04 CN CN201510058282.5A patent/CN105985244A/en active Pending
-
2016
- 2016-01-27 AU AU2016214849A patent/AU2016214849B2/en active Active
- 2016-01-27 US US15/548,760 patent/US10099998B2/en active Active
- 2016-01-27 CN CN201680007999.XA patent/CN107207404B/en active Active
- 2016-01-27 KR KR1020177024626A patent/KR102160471B1/en active IP Right Grant
- 2016-01-27 SG SG11201706353WA patent/SG11201706353WA/en unknown
- 2016-01-27 MY MYPI2017702865A patent/MY188671A/en unknown
- 2016-01-27 WO PCT/CN2016/072306 patent/WO2016124087A1/en active Application Filing
- 2016-01-27 EP EP16746082.3A patent/EP3255031B1/en active Active
- 2016-01-27 JP JP2017541085A patent/JP6686032B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018505884A (en) | 2018-03-01 |
| KR102160471B1 (en) | 2020-09-29 |
| CN107207404A (en) | 2017-09-26 |
| CN107207404B (en) | 2021-07-13 |
| JP6686032B2 (en) | 2020-04-22 |
| CN105985244A (en) | 2016-10-05 |
| US10099998B2 (en) | 2018-10-16 |
| WO2016124087A1 (en) | 2016-08-11 |
| MY188671A (en) | 2021-12-22 |
| EP3255031A1 (en) | 2017-12-13 |
| AU2016214849B2 (en) | 2020-05-07 |
| EP3255031A4 (en) | 2018-09-26 |
| KR20170134344A (en) | 2017-12-06 |
| EP3255031B1 (en) | 2021-09-29 |
| AU2016214849A1 (en) | 2017-08-24 |
| US20180022688A1 (en) | 2018-01-25 |
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