SG11201703296PA - Heterocyclic derivatives and use thereof - Google Patents
Heterocyclic derivatives and use thereofInfo
- Publication number
- SG11201703296PA SG11201703296PA SG11201703296PA SG11201703296PA SG11201703296PA SG 11201703296P A SG11201703296P A SG 11201703296PA SG 11201703296P A SG11201703296P A SG 11201703296PA SG 11201703296P A SG11201703296P A SG 11201703296PA SG 11201703296P A SG11201703296P A SG 11201703296PA
- Authority
- SG
- Singapore
- Prior art keywords
- heterocyclic derivatives
- heterocyclic
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20140170860 | 2014-12-02 | ||
| KR1020150128025A KR20160066490A (en) | 2014-12-02 | 2015-09-10 | Heterocyclic derivatives and use thereof |
| PCT/KR2015/012926 WO2016089062A2 (en) | 2014-12-02 | 2015-11-30 | Heterocyclic derivatives and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201703296PA true SG11201703296PA (en) | 2017-05-30 |
Family
ID=56092629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201703296PA SG11201703296PA (en) | 2014-12-02 | 2015-11-30 | Heterocyclic derivatives and use thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US10023591B2 (en) |
| EP (2) | EP3227270A4 (en) |
| JP (2) | JP6640222B2 (en) |
| KR (3) | KR20160066490A (en) |
| CN (2) | CN107231802B (en) |
| AU (2) | AU2015355839B2 (en) |
| BR (1) | BR112017011316B1 (en) |
| CA (2) | CA2966742A1 (en) |
| IL (1) | IL252560B (en) |
| MX (2) | MX2017006165A (en) |
| MY (1) | MY194314A (en) |
| PH (1) | PH12017550004B1 (en) |
| RU (2) | RU2734390C2 (en) |
| SG (1) | SG11201703296PA (en) |
| TW (2) | TWI691484B (en) |
| WO (1) | WO2016089060A2 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7114394B2 (en) * | 2017-08-18 | 2022-08-08 | 住友化学株式会社 | Compound, resist composition and method for producing resist pattern |
| CN107973788B (en) * | 2018-01-09 | 2021-07-09 | 沈阳药科大学 | BBI608 derivative and preparation and application thereof |
| CN109045013A (en) * | 2018-06-20 | 2018-12-21 | 新乡医学院第附属医院 | The new medical use of Nifuroxazide |
| CA3135802A1 (en) | 2019-04-05 | 2020-10-08 | Kymera Therapeutics, Inc. | Stat degraders and uses thereof |
| KR102426921B1 (en) * | 2019-09-24 | 2022-07-29 | 주식회사 이노보테라퓨틱스 | Heteroarylamidopyridinol derivatives and pharmaceutical composition for use in preventing or treating autoimmune diseases containing the same as an active ingredient |
| JP2022552735A (en) | 2019-10-25 | 2022-12-19 | ギリアード サイエンシーズ， インコーポレイテッド | GLP-1R modulating compounds |
| WO2021100942A1 (en) * | 2019-11-22 | 2021-05-27 | 재단법인 한국파스퇴르연구소 | Thienothiazolecarboxamide derivative which is antituberculous compound |
| US20230121233A1 (en) * | 2020-01-02 | 2023-04-20 | Accro Bioscience Inc. | Heteroaryl compounds as inhibitors of programmed necrosis pathway, composition and method using the same |
| CN113150009B (en) * | 2020-01-07 | 2023-05-23 | 爱科诺生物医药(香港)有限公司 | Heterocyclic compound with activity of inhibiting programmed cell necrosis pathway and application thereof |
| WO2022109182A1 (en) | 2020-11-20 | 2022-05-27 | Gilead Sciences, Inc. | Polyheterocyclic glp-1 r modulating compounds |
| EP4304711A1 (en) | 2021-03-11 | 2024-01-17 | Gilead Sciences, Inc. | Glp-1r modulating compounds |
| MX2023012418A (en) | 2021-04-21 | 2023-10-31 | Gilead Sciences Inc | Carboxy-benzimidazole glp-1r modulating compounds. |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5210090A (en) | 1989-09-05 | 1993-05-11 | G. D. Searle & Co. | Substituted N-benzylpiperidine amides and cardiac regulatory compositions thereof |
| GB9215361D0 (en) * | 1992-07-20 | 1992-09-02 | Wellcome Found | Heterocyclic compounds |
| AU688112B2 (en) * | 1994-08-22 | 1998-03-05 | Eli Lilly And Company | Methods of inhibiting endometrial cancer |
| EP0945438B1 (en) * | 1996-12-12 | 2003-03-05 | Banyu Pharmaceutical Co., Ltd. | Pyrazole derivatives |
| CA2450628A1 (en) | 2001-06-13 | 2002-12-19 | Genesoft Pharmaceuticals, Inc. | Benzothiophene compounds having antiinfective activity |
| US20040142981A1 (en) | 2002-08-23 | 2004-07-22 | Atli Thorarensen | Antibacterial benzoic acid derivatives |
| AU2003275056A1 (en) * | 2002-09-17 | 2004-04-08 | Arqule, Inc. | Novel lapacho compounds and methods of use thereof |
| BR0318640A (en) | 2003-12-04 | 2006-11-28 | Wyeth Corp | biaryl sulfonamides as inhibitors of mmp |
| EP1598353A1 (en) | 2004-05-17 | 2005-11-23 | Boehringer Ingelheim International GmbH | Pyrrolobenzimidazolones and their use as antiproliferative agents |
| EP1954287B2 (en) * | 2005-10-31 | 2016-02-24 | Merck Sharp & Dohme Corp. | Cetp inhibitors |
| UA95978C2 (en) * | 2006-10-02 | 2011-09-26 | Оцука Фармас'Ютікел Ко., Лтд. | Stat3/5 activation inhibitor |
| WO2008124000A2 (en) * | 2007-04-02 | 2008-10-16 | Ligand Pharmaceuticals Incorporated | Thiazole derivatives as androgen receptor modulator compounds |
| CN101854802B (en) * | 2007-09-10 | 2014-12-03 | 北京强新生物科技有限公司 | Novel compositions and methods for cancer treatment |
| ES2622575T3 (en) * | 2008-07-10 | 2017-07-06 | General Incorporated Association Pharma Valley Project Supporting Organization | STAT3 inhibitor containing a quinolincarboxamide derivative as active ingredient |
| EP2430015B1 (en) * | 2009-05-12 | 2015-06-17 | Merck Sharp & Dohme Corp. | Fused tricyclic compounds useful for the treatment of viral diseases |
| JP2012529518A (en) * | 2009-06-09 | 2012-11-22 | アブラクシス バイオサイエンス リミテッド ライアビリティー カンパニー | Pyridyl-triazine inhibitors of hedgehog signaling |
| DK2470173T3 (en) * | 2009-08-25 | 2016-06-06 | Abraxis Bioscience Llc | Combination therapy of nanoparticle composition of the taxane and the hedgehog inhibitors |
| US20140357633A1 (en) | 2011-12-23 | 2014-12-04 | Novartis Ag | Compounds for inhibiting the interaction of bcl2 with binding partners |
| EP3004057B1 (en) * | 2013-06-05 | 2018-07-25 | C&C Research Laboratories | Heterocyclic derivatives and their use as stat 3 inhibitors |
| EP3125883B1 (en) * | 2014-04-04 | 2020-08-12 | Iomet Pharma Ltd. | Indole derivatives for use in medicine |
-
2015
- 2015-09-10 KR KR1020150128025A patent/KR20160066490A/en unknown
- 2015-11-30 EP EP15864809.7A patent/EP3227270A4/en active Pending
- 2015-11-30 KR KR1020177017836A patent/KR102534262B1/en active IP Right Grant
- 2015-11-30 BR BR112017011316-3A patent/BR112017011316B1/en active IP Right Grant
- 2015-11-30 WO PCT/KR2015/012920 patent/WO2016089060A2/en active Application Filing
- 2015-11-30 CN CN201580062816.XA patent/CN107231802B/en active Active
- 2015-11-30 CA CA2966742A patent/CA2966742A1/en active Pending
- 2015-11-30 JP JP2017529771A patent/JP6640222B2/en active Active
- 2015-11-30 SG SG11201703296PA patent/SG11201703296PA/en unknown
- 2015-11-30 AU AU2015355839A patent/AU2015355839B2/en active Active
- 2015-11-30 MY MYPI2017701759A patent/MY194314A/en unknown
- 2015-11-30 CA CA2966759A patent/CA2966759C/en active Active
- 2015-11-30 JP JP2017529772A patent/JP6648137B2/en active Active
- 2015-11-30 EP EP15865425.1A patent/EP3227271A4/en active Pending
- 2015-11-30 KR KR1020177017839A patent/KR102534266B1/en active IP Right Grant
- 2015-11-30 US US15/526,415 patent/US10023591B2/en active Active
- 2015-11-30 RU RU2017123170A patent/RU2734390C2/en active
- 2015-11-30 CN CN201580063393.3A patent/CN107001345B/en active Active
- 2015-11-30 AU AU2015355841A patent/AU2015355841B2/en active Active
- 2015-11-30 MX MX2017006165A patent/MX2017006165A/en unknown
- 2015-11-30 MX MX2017006224A patent/MX2017006224A/en unknown
- 2015-11-30 US US15/528,571 patent/US10633394B2/en active Active
- 2015-11-30 RU RU2017120973A patent/RU2711502C2/en active
- 2015-12-01 TW TW104140106A patent/TWI691484B/en active
- 2015-12-01 TW TW104140107A patent/TWI687423B/en active
-
2017
- 2017-05-05 PH PH12017550004A patent/PH12017550004B1/en unknown
- 2017-05-28 IL IL252560A patent/IL252560B/en active IP Right Grant
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