SG11201703280TA - Strontium phosphate microparticle for radiological imaging and therapy - Google Patents

Strontium phosphate microparticle for radiological imaging and therapy

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Publication number
SG11201703280TA
SG11201703280TA SG11201703280TA SG11201703280TA SG11201703280TA SG 11201703280T A SG11201703280T A SG 11201703280TA SG 11201703280T A SG11201703280T A SG 11201703280TA SG 11201703280T A SG11201703280T A SG 11201703280TA SG 11201703280T A SG11201703280T A SG 11201703280TA
Authority
SG
Singapore
Prior art keywords
therapy
radiological imaging
strontium phosphate
phosphate microparticle
microparticle
Prior art date
Application number
SG11201703280TA
Other languages
English (en)
Inventor
Delbert E Day
Yiyong He
Original Assignee
Mo Sci Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mo Sci Corp filed Critical Mo Sci Corp
Publication of SG11201703280TA publication Critical patent/SG11201703280TA/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A61K51/1244Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
    • A61K51/1251Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles micro- or nanospheres, micro- or nanobeads, micro- or nanocapsules
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    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0489Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
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    • C01B25/00Phosphorus; Compounds thereof
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SG11201703280TA 2014-10-21 2014-10-21 Strontium phosphate microparticle for radiological imaging and therapy SG11201703280TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2014/061597 WO2016064379A1 (fr) 2010-09-16 2014-10-21 Microparticules de phosphate de strontium pour l'imagerie et la thérapie radiologiques

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SG11201703280TA true SG11201703280TA (en) 2017-05-30

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EP (1) EP3209337B1 (fr)
JP (1) JP6608925B2 (fr)
KR (1) KR102253251B1 (fr)
CN (1) CN107073142B (fr)
AU (1) AU2014409581B2 (fr)
CA (1) CA2965308C (fr)
SG (1) SG11201703280TA (fr)
WO (1) WO2016064379A1 (fr)
ZA (1) ZA201703327B (fr)

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WO2020047662A1 (fr) * 2018-09-05 2020-03-12 Ir Scientific Inc. Composition de verre
US20220184238A1 (en) * 2019-03-29 2022-06-16 National Institutes for Quantum Science and Technology Radiolabeled Compound Producing Method and Producing Apparatus, Radiolabeled Compound and Radioisotope Producing Apparatus
WO2020206459A1 (fr) * 2019-04-05 2020-10-08 Northeastern University Biosynthèse de nanoparticules de sélénium ayant une activité antimicrobienne
JP2022547277A (ja) 2019-09-16 2022-11-11 エービーケー バイオメディカル インコーポレイテッド 放射性微粒子及び非放射性微粒子の組成物
WO2022170206A1 (fr) * 2021-02-08 2022-08-11 University Of Virginia Patent Foundation Particules fonctionnalisées avec des radio-isotopes thérapeutiques et leurs procédés de fabrication et d'utilisation

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
US5011797A (en) * 1988-01-29 1991-04-30 The Curators Of The University Of Missouri Composition and method for radiation synovectomy of arthritic joints
US6537518B1 (en) * 1994-01-21 2003-03-25 Sirtex Medical Limited Particulate material
ATE281886T1 (de) * 1994-01-21 2004-11-15 Sirtex Medical Ltd Yttria partikelförmiges gut
AU1064800A (en) * 1998-11-12 2000-06-05 Nycomed Amersham Plc Products and methods
WO2005087274A1 (fr) 2004-03-05 2005-09-22 Xl Sci-Tech, Inc. Materiaux pulverulents et compositions de radiotherapie
EP2461840A4 (fr) * 2009-08-04 2013-11-06 Biomatcell Ab Particules de phosphate de calcium à substitution ionique
CN102671219B (zh) * 2011-03-11 2013-12-11 成都云克药业有限责任公司 一种放射性阴离子树脂微球及其制备方法

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CN107073142A (zh) 2017-08-18
CA2965308A1 (fr) 2016-04-28
ZA201703327B (en) 2018-08-29
KR20170066658A (ko) 2017-06-14
EP3209337A1 (fr) 2017-08-30
JP6608925B2 (ja) 2019-11-20
CN107073142B (zh) 2021-02-05
WO2016064379A1 (fr) 2016-04-28
AU2014409581B2 (en) 2020-09-03
JP2018502054A (ja) 2018-01-25
CA2965308C (fr) 2023-02-28
AU2014409581A1 (en) 2017-05-25
EP3209337B1 (fr) 2021-03-31
KR102253251B1 (ko) 2021-05-17

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