SG11201701645WA - Pharmaceutical compositions comprising a dextromethorphan compound and quinidine for the treatment of agitation in dementia - Google Patents
Pharmaceutical compositions comprising a dextromethorphan compound and quinidine for the treatment of agitation in dementiaInfo
- Publication number
- SG11201701645WA SG11201701645WA SG11201701645WA SG11201701645WA SG11201701645WA SG 11201701645W A SG11201701645W A SG 11201701645WA SG 11201701645W A SG11201701645W A SG 11201701645WA SG 11201701645W A SG11201701645W A SG 11201701645WA SG 11201701645W A SG11201701645W A SG 11201701645WA
- Authority
- SG
- Singapore
- Prior art keywords
- quinidine
- dementia
- agitation
- treatment
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/49—Cinchonan derivatives, e.g. quinine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462050170P | 2014-09-14 | 2014-09-14 | |
US201462061451P | 2014-10-08 | 2014-10-08 | |
US201462063122P | 2014-10-13 | 2014-10-13 | |
US201462063861P | 2014-10-14 | 2014-10-14 | |
US201462068742P | 2014-10-26 | 2014-10-26 | |
US201562111053P | 2015-02-02 | 2015-02-02 | |
US201562111590P | 2015-02-03 | 2015-02-03 | |
US201562128446P | 2015-03-04 | 2015-03-04 | |
US201562162140P | 2015-05-15 | 2015-05-15 | |
US201562165535P | 2015-05-22 | 2015-05-22 | |
US201562169997P | 2015-06-02 | 2015-06-02 | |
US201562180026P | 2015-06-15 | 2015-06-15 | |
US201562193347P | 2015-07-16 | 2015-07-16 | |
US201562205061P | 2015-08-14 | 2015-08-14 | |
US201562216636P | 2015-09-10 | 2015-09-10 | |
US201562217470P | 2015-09-11 | 2015-09-11 | |
US201562217142P | 2015-09-11 | 2015-09-11 | |
PCT/US2015/049934 WO2016040930A1 (en) | 2014-09-14 | 2015-09-14 | Pharmaceutical compositions comprising a dextromethorphan compound and quinidine for the treatment of agitation in dementia |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201701645WA true SG11201701645WA (en) | 2017-04-27 |
Family
ID=55459653
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201701645WA SG11201701645WA (en) | 2014-09-14 | 2015-09-14 | Pharmaceutical compositions comprising a dextromethorphan compound and quinidine for the treatment of agitation in dementia |
SG10201901242PA SG10201901242PA (en) | 2014-09-14 | 2015-09-14 | Pharmaceutical compositions comprising a dextromethorphan compound and quinidine for the treatment of agitation in dementia |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201901242PA SG10201901242PA (en) | 2014-09-14 | 2015-09-14 | Pharmaceutical compositions comprising a dextromethorphan compound and quinidine for the treatment of agitation in dementia |
Country Status (14)
Country | Link |
---|---|
US (3) | US20190111047A1 (zh) |
EP (4) | EP4166141A1 (zh) |
JP (4) | JP2017531033A (zh) |
KR (1) | KR20170052684A (zh) |
CN (3) | CN107072990A (zh) |
AU (3) | AU2015314710A1 (zh) |
CA (1) | CA2960031A1 (zh) |
IL (2) | IL250786A0 (zh) |
MX (3) | MX2017003066A (zh) |
PH (1) | PH12017500444A1 (zh) |
RU (2) | RU2017112747A (zh) |
SG (2) | SG11201701645WA (zh) |
TW (3) | TW202231278A (zh) |
WO (1) | WO2016040930A1 (zh) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20180243289A1 (en) * | 2015-07-30 | 2018-08-30 | Concert Pharmaceuticals, Inc. | Deuterated morphinan compounds for treating agitation |
CA2994153A1 (en) * | 2015-07-30 | 2017-02-02 | Concert Pharmaceuticals, Inc. | Deuterated morphinan compounds for use in treating agitation |
KR20230017361A (ko) * | 2016-07-04 | 2023-02-03 | 아바니르 파마슈티컬스, 인코포레이티드 | 중수소화 덱스트로메토르판의 합성 방법 |
US11478467B2 (en) | 2017-05-04 | 2022-10-25 | Sreenivasarao Vepachedu | Targeted drug rescue with novel compositions, combinations, and methods thereof |
CA3100897A1 (en) * | 2018-05-18 | 2019-11-21 | Anavex Life Sciences Corp. | Optimized sigma-1 agonist method of responder selection and treatment |
CR20210368A (es) * | 2019-01-07 | 2021-12-10 | Antecip Bioventures Ii Llc | Combinación de dextrometorfano y bupropión para el tratamiento de depresión |
SG11202110150YA (en) * | 2019-03-18 | 2021-10-28 | Avanir Pharmaceuticals Inc | Methods of treating negative symptoms of schizophrenia using deuterated dextromethorphan and quinidine |
KR20230016636A (ko) * | 2020-04-27 | 2023-02-02 | 아바니르 파마슈티컬스, 인코포레이티드 | 알츠하이머병과 관련된 불안을 치료하는 방법 |
WO2022228363A1 (zh) * | 2021-04-27 | 2022-11-03 | 杭州剂泰医药科技有限责任公司 | 一种组合物的医药用途 |
CN113209042A (zh) * | 2021-05-28 | 2021-08-06 | 珠海润都制药股份有限公司 | 一种氢溴酸右美沙芬硫酸奎尼丁胶囊及其制备方法 |
CA3236017A1 (en) * | 2021-10-27 | 2023-05-04 | Sanjay Dube | Methods of treating agitation associated with alzheimer's disease |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
US5366980A (en) | 1991-06-17 | 1994-11-22 | Smith Richard A | Use of dextromethorphan and an oxidase inhibitor to treat dermatitis |
US5350756A (en) | 1991-06-17 | 1994-09-27 | Smith Richard A | Use of a cytochrome oxidase inhibitor to increase the cough-suppressing activity of dextromorphan |
US5206248A (en) | 1992-03-27 | 1993-04-27 | Smith Richard A | Method for reducing emotional lability |
US5166207A (en) | 1991-06-17 | 1992-11-24 | Neurotherapeutics, Inc. | Method for enhancing the systemic delivery of dextromethorphan for the treatment of neurological disorders |
TW264473B (zh) * | 1993-01-06 | 1995-12-01 | Hoffmann La Roche | |
EP1634597A1 (en) * | 1994-09-22 | 2006-03-15 | Richard Alan Smith | Compositions comprising dextromethorphan and quinidine or quinine for the treatment of emotional lability |
US5874443A (en) | 1995-10-19 | 1999-02-23 | Trega Biosciences, Inc. | Isoquinoline derivatives and isoquinoline combinatorial libraries |
US5886210A (en) | 1996-08-22 | 1999-03-23 | Rohm And Haas Company | Method for preparing aromatic compounds |
US5922683A (en) | 1997-05-29 | 1999-07-13 | Abbott Laboratories | Multicyclic erythromycin derivatives |
US6479484B1 (en) | 1997-11-21 | 2002-11-12 | Euro-Celtique S.A. | Substituted 2-aminoacetamides and the use thereof |
PL343249A1 (en) | 1998-03-26 | 2001-07-30 | Shionogi & Co | Indole derivatives with antiviral activity |
US6509331B1 (en) | 1998-06-22 | 2003-01-21 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
FR2784988B1 (fr) | 1998-10-23 | 2002-09-20 | Adir | Nouveaux composes dihydro et tetrahydroquinoleiniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
TWI326214B (en) * | 2002-07-17 | 2010-06-21 | Avanir Pharmaceuticals Inc | Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders |
CA2641392A1 (en) * | 2006-02-03 | 2007-08-16 | Avanir Pharmaceuticals | Pharmaceutical compositions for treating depression, anxiety and neurodegenerative disorders |
US20070224128A1 (en) * | 2006-03-07 | 2007-09-27 | Donn Michael Dennis | Drug adherence monitoring system |
WO2008097924A2 (en) * | 2007-02-05 | 2008-08-14 | Avanir Pharmaceuticals | Pharmaceutical compositions comprising dextromethorphan analogs for the treatment of neurological disorders |
DK2345653T3 (da) * | 2007-05-01 | 2013-04-08 | Concert Pharmaceuticals Inc | Morphinanforbindelser |
ES2402088T3 (es) * | 2008-09-19 | 2013-04-26 | Concert Pharmaceuticals Inc. | Compuestos de morfinano |
EP3090760A1 (en) * | 2008-10-30 | 2016-11-09 | Concert Pharmaceuticals, Inc. | Combination of morphinan compounds and antidepressant for the treatment of pseudobulbar affect, neurological diseases, intractable and chronic pain and brain injury |
CA2743902C (en) * | 2008-11-14 | 2016-09-20 | Concert Pharmaceuticals, Inc. | Substituted dioxopiperidinyl phthalimide derivatives |
NZ758431A (en) * | 2013-11-05 | 2021-07-30 | Antecip Bioventures Ii Llc | Compositions and methods comprising bupropion or related compounds and dextromethorphan |
-
2015
- 2015-09-14 SG SG11201701645WA patent/SG11201701645WA/en unknown
- 2015-09-14 EP EP22195837.4A patent/EP4166141A1/en active Pending
- 2015-09-14 CN CN201580049454.0A patent/CN107072990A/zh active Pending
- 2015-09-14 RU RU2017112747A patent/RU2017112747A/ru not_active Application Discontinuation
- 2015-09-14 CN CN201910903770.XA patent/CN110664801A/zh active Pending
- 2015-09-14 KR KR1020177009991A patent/KR20170052684A/ko not_active Application Discontinuation
- 2015-09-14 JP JP2017533726A patent/JP2017531033A/ja active Pending
- 2015-09-14 SG SG10201901242PA patent/SG10201901242PA/en unknown
- 2015-09-14 TW TW110139834A patent/TW202231278A/zh unknown
- 2015-09-14 RU RU2020116666A patent/RU2020116666A/ru unknown
- 2015-09-14 AU AU2015314710A patent/AU2015314710A1/en not_active Abandoned
- 2015-09-14 MX MX2017003066A patent/MX2017003066A/es unknown
- 2015-09-14 EP EP21178170.3A patent/EP3932907A3/en not_active Withdrawn
- 2015-09-14 EP EP15840718.9A patent/EP3193872A4/en not_active Withdrawn
- 2015-09-14 TW TW109114123A patent/TW202106301A/zh unknown
- 2015-09-14 EP EP20159783.8A patent/EP3708168A3/en not_active Withdrawn
- 2015-09-14 CN CN202311175974.9A patent/CN117427077A/zh active Pending
- 2015-09-14 WO PCT/US2015/049934 patent/WO2016040930A1/en active Application Filing
- 2015-09-14 TW TW104130311A patent/TW201613591A/zh unknown
- 2015-09-14 US US15/510,498 patent/US20190111047A1/en not_active Abandoned
- 2015-09-14 CA CA2960031A patent/CA2960031A1/en active Pending
-
2017
- 2017-02-26 IL IL250786A patent/IL250786A0/en unknown
- 2017-03-08 MX MX2021010696A patent/MX2021010696A/es unknown
- 2017-03-08 MX MX2022008181A patent/MX2022008181A/es unknown
- 2017-03-09 PH PH12017500444A patent/PH12017500444A1/en unknown
-
2019
- 2019-10-08 US US16/596,236 patent/US20200289499A1/en not_active Abandoned
- 2019-11-06 JP JP2019201410A patent/JP2020019818A/ja not_active Withdrawn
-
2020
- 2020-05-18 IL IL274742A patent/IL274742A/en unknown
- 2020-12-15 AU AU2020289733A patent/AU2020289733A1/en not_active Abandoned
-
2021
- 2021-03-08 JP JP2021036318A patent/JP7360409B2/ja active Active
-
2022
- 2022-12-06 AU AU2022283671A patent/AU2022283671A1/en active Pending
-
2023
- 2023-04-24 US US18/305,589 patent/US20240082237A1/en active Pending
- 2023-06-12 JP JP2023096152A patent/JP2023105265A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL274742A (en) | Pharmaceutical preparations containing the compound dextromethorphan and quinidine for the treatment of restlessness in dementia | |
IL272820A (en) | History of sulfamolepyrolamide and their use as hepatitis B drugs | |
HK1258205A1 (zh) | 用於治療血紅蛋白病的組合物和方法 | |
ZA201707303B (en) | Compositions and methods for the treatment of immunodeficiency | |
IL265970B (en) | Sulfoxyalkyl organonitro compounds and related compounds and pharmaceutical preparations for use in medicine | |
GB201400442D0 (en) | Compositions for use in the treatment of ulcerative colitis | |
HK1254054A1 (zh) | 富馬酸二甲酯顆粒和其藥物組合物 | |
PL3129057T3 (pl) | Glikolipidy i ich kompozycje farmaceutyczne do stosowania w leczeniu | |
PL3373922T3 (pl) | Kompozycje i sposoby do stosowania do leczenia homocystynurii | |
HK1245113A1 (zh) | 藥物組合物及其用途 | |
IL251345B (en) | Preparations for use in the treatment of peri-implantitis | |
IL249440B (en) | Pharmaceutical compounds and preparations containing them for the treatment of neurodegenerative diseases | |
FI3842436T3 (fi) | Imidatsopyrimidiini- tai imidatsotriatsiinijohdannaisia käsittäviä farmaseuttisia koostumuksia käytettäväksi skitsofrenian hoidossa | |
SG11201609701UA (en) | Pharmaceutical composition for preventing and treating senile dementia and preparation method thereof | |
SI3548006T1 (sl) | Sestava za uporabo pri zdravljenju črevesnih sprememb | |
GB201616880D0 (en) | Compound for use in medicine | |
SG11201704282UA (en) | Compositions and methods for the treatment of multiple sclerosis |