SG11201610126RA - Systems and methods for synthetic biology design and host cell simulation - Google Patents

Systems and methods for synthetic biology design and host cell simulation

Info

Publication number
SG11201610126RA
SG11201610126RA SG11201610126RA SG11201610126RA SG11201610126RA SG 11201610126R A SG11201610126R A SG 11201610126RA SG 11201610126R A SG11201610126R A SG 11201610126RA SG 11201610126R A SG11201610126R A SG 11201610126RA SG 11201610126R A SG11201610126R A SG 11201610126RA
Authority
SG
Singapore
Prior art keywords
systems
methods
host cell
synthetic biology
cell simulation
Prior art date
Application number
SG11201610126RA
Other languages
English (en)
Inventor
Premkumar Jayaraman
Chueh Loo Poh
hui juan Wang
Original Assignee
Univ Nanyang Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nanyang Tech filed Critical Univ Nanyang Tech
Publication of SG11201610126RA publication Critical patent/SG11201610126RA/en

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G06F17/11—Complex mathematical operations for solving equations, e.g. nonlinear equations, general mathematical optimization problems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G16B5/30—Dynamic-time models
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Theoretical Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • General Physics & Mathematics (AREA)
  • Mathematical Physics (AREA)
  • Pure & Applied Mathematics (AREA)
  • Mathematical Analysis (AREA)
  • Data Mining & Analysis (AREA)
  • Computational Mathematics (AREA)
  • Mathematical Optimization (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Library & Information Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Computing Systems (AREA)
  • Operations Research (AREA)
  • Algebra (AREA)
  • Databases & Information Systems (AREA)
  • Software Systems (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201610126RA 2014-06-27 2015-06-19 Systems and methods for synthetic biology design and host cell simulation SG11201610126RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462018078P 2014-06-27 2014-06-27
PCT/SG2015/050169 WO2015199614A1 (en) 2014-06-27 2015-06-19 Systems and methods for synthetic biology design and host cell simulation

Publications (1)

Publication Number Publication Date
SG11201610126RA true SG11201610126RA (en) 2017-01-27

Family

ID=54938549

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201610126RA SG11201610126RA (en) 2014-06-27 2015-06-19 Systems and methods for synthetic biology design and host cell simulation

Country Status (5)

Country Link
US (1) US20170147742A1 (de)
EP (1) EP3161697A4 (de)
CN (1) CN106663146A (de)
SG (1) SG11201610126RA (de)
WO (1) WO2015199614A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3007635A1 (en) 2015-12-07 2017-06-15 Zymergen Inc. Promoters from corynebacterium glutamicum
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
US10544390B2 (en) 2016-06-30 2020-01-28 Zymergen Inc. Methods for generating a bacterial hemoglobin library and uses thereof
EP3478845A4 (de) 2016-06-30 2019-07-31 Zymergen, Inc. Verfahren zur erzeugung einer glucose-permease-bibliothek und verwendungen davon
US10892034B2 (en) 2016-07-01 2021-01-12 Microsoft Technology Licensing, Llc Use of homology direct repair to record timing of a molecular event
US11359234B2 (en) 2016-07-01 2022-06-14 Microsoft Technology Licensing, Llc Barcoding sequences for identification of gene expression
WO2018005117A1 (en) 2016-07-01 2018-01-04 Microsoft Technology Licensing, Llc Storage through iterative dna editing
WO2018152243A2 (en) * 2017-02-15 2018-08-23 Zymergen Inc. Bioreachable prediction tool
WO2020005628A1 (en) * 2018-06-28 2020-01-02 Microsoft Technology Licensing, Llc Dynamic characterization of synthetic genetic circuits in living cells
GB201810636D0 (en) * 2018-06-28 2018-08-15 Microsoft Technology Licensing Llc Dynamic characterisation of synthetic genetic circuits in living cells
US11393555B1 (en) * 2018-09-06 2022-07-19 X Development Llc Dynamic coordinating framework for model cell simulations
GB201900742D0 (en) 2019-01-18 2019-03-06 Microsoft Technology Licensing Llc Modelling ordinary differential equations using a variational auto encoder
CN110656121B (zh) * 2019-10-29 2022-04-29 江南大学 一种调控大肠杆菌细胞大小的方法
US20220036975A1 (en) * 2020-07-29 2022-02-03 X Development Llc Kinematic modeling of biochemical pathways
CN112562782B (zh) * 2020-12-16 2024-02-09 中国科学院深圳先进技术研究院 一种合成基因回路模型的构建方法
US11797274B2 (en) * 2021-06-22 2023-10-24 Altered State Machine Limited Interoperable composite data units for use in distributed computing execution environments

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2342664A1 (de) * 2008-09-03 2011-07-13 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Computerimplementiertes modell biologischer netzwerke
CN102459650B (zh) * 2009-06-08 2014-10-01 韩国生命工学研究院 采用人工基因线路筛选及量化各种酶活性的方法
US9697460B2 (en) * 2009-11-30 2017-07-04 Trustees Of Boston University Biological analog-to-digital and digital-to-analog converters
WO2011153372A2 (en) * 2010-06-02 2011-12-08 Board Of Regents Of The University Of Texas System Methods and systems for simulations of complex biological networks using gene expression indexing in computational models
WO2014015196A2 (en) * 2012-07-18 2014-01-23 The Board Of Trustees Of The Leland Stanford Junior University Techniques for predicting phenotype from genotype based on a whole cell computational model
US9691017B2 (en) * 2012-12-13 2017-06-27 Massachusetts Institute Of Technology Recombinase-based logic and memory systems
US20140180660A1 (en) * 2012-12-14 2014-06-26 Life Technologies Holdings Pte Limited Methods and systems for in silico design

Also Published As

Publication number Publication date
EP3161697A4 (de) 2018-03-14
US20170147742A1 (en) 2017-05-25
CN106663146A (zh) 2017-05-10
WO2015199614A1 (en) 2015-12-30
EP3161697A1 (de) 2017-05-03

Similar Documents

Publication Publication Date Title
SG11201610126RA (en) Systems and methods for synthetic biology design and host cell simulation
HK1244554A1 (zh) 用於智能空間的系統和方法
HK1252457A1 (zh) 拼車方法及系統
EP3164768A4 (de) Systeme und verfahren für flugsimulation
GB201717264D0 (en) Systems and methods for carpooling
SG11201701855RA (en) Systems and methods for liveness analysis
EP3117347A4 (de) Systeme und verfahren zur schnellen datenanalyse
SG11201704316YA (en) Methods and apparatuses for haptic systems
EP3095054A4 (de) Verfahren und systeme zur genomanalyse
EP2976687A4 (de) Systeme und verfahren zur uav-andockung
IL239972B (en) Systems and methods for prenatal genetic analysis
HK1255101A1 (zh) 用於得到調節性t細胞的方法及其用途
EP3192861A4 (de) System zur evaluierung von zellkulturen und verfahren zur evaluierung von zellkulturen
SG11201704498QA (en) Computing systems and methods
SG11201607836WA (en) Inspection methods and systems
SG10201500398VA (en) Systems and Methods for Creating and Evaluating Experiments
EP3195073A4 (de) Systeme und verfahren für prozessdesign und -analyse
SI3131577T1 (sl) Modificirane gostiljske celice in uporabe le-teh
PT3136841T (pt) Sistemas de fermentação
SG11201609292QA (en) Panel systems and methods
EP3332215A4 (de) Systeme und verfahren zur nordfindung
GB201522792D0 (en) Systems and methods for modifying access to media assests
GB2550716B (en) Sonar data enhancement systems and methods
EP3196293C0 (de) Dreidimensionales zellkultursystem und zellkulturverfahren damit
GB2533110B (en) Media system analysis and control