SG11201610126RA - Systems and methods for synthetic biology design and host cell simulation - Google Patents
Systems and methods for synthetic biology design and host cell simulationInfo
- Publication number
- SG11201610126RA SG11201610126RA SG11201610126RA SG11201610126RA SG11201610126RA SG 11201610126R A SG11201610126R A SG 11201610126RA SG 11201610126R A SG11201610126R A SG 11201610126RA SG 11201610126R A SG11201610126R A SG 11201610126RA SG 11201610126R A SG11201610126R A SG 11201610126RA
- Authority
- SG
- Singapore
- Prior art keywords
- systems
- methods
- host cell
- synthetic biology
- cell simulation
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
- G06F17/10—Complex mathematical operations
- G06F17/11—Complex mathematical operations for solving equations, e.g. nonlinear equations, general mathematical optimization problems
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
- G16B5/30—Dynamic-time models
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/60—In silico combinatorial chemistry
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462018078P | 2014-06-27 | 2014-06-27 | |
| PCT/SG2015/050169 WO2015199614A1 (en) | 2014-06-27 | 2015-06-19 | Systems and methods for synthetic biology design and host cell simulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201610126RA true SG11201610126RA (en) | 2017-01-27 |
Family
ID=54938549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201610126RA SG11201610126RA (en) | 2014-06-27 | 2015-06-19 | Systems and methods for synthetic biology design and host cell simulation |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170147742A1 (en) |
| EP (1) | EP3161697A4 (en) |
| CN (1) | CN106663146A (en) |
| SG (1) | SG11201610126RA (en) |
| WO (1) | WO2015199614A1 (en) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9988624B2 (en) | 2015-12-07 | 2018-06-05 | Zymergen Inc. | Microbial strain improvement by a HTP genomic engineering platform |
| CA3007635A1 (en) | 2015-12-07 | 2017-06-15 | Zymergen Inc. | Promoters from corynebacterium glutamicum |
| US11208649B2 (en) | 2015-12-07 | 2021-12-28 | Zymergen Inc. | HTP genomic engineering platform |
| WO2018005655A2 (en) | 2016-06-30 | 2018-01-04 | Zymergen Inc. | Methods for generating a bacterial hemoglobin library and uses thereof |
| WO2018005793A1 (en) | 2016-06-30 | 2018-01-04 | Zymergen Inc. | Methods for generating a glucose permease library and uses thereof |
| US11359234B2 (en) | 2016-07-01 | 2022-06-14 | Microsoft Technology Licensing, Llc | Barcoding sequences for identification of gene expression |
| EP3478852B1 (en) | 2016-07-01 | 2020-08-12 | Microsoft Technology Licensing, LLC | Storage through iterative dna editing |
| US10892034B2 (en) | 2016-07-01 | 2021-01-12 | Microsoft Technology Licensing, Llc | Use of homology direct repair to record timing of a molecular event |
| CA3050749A1 (en) * | 2017-02-15 | 2018-08-23 | Zymergen Inc. | Bioreachable prediction tool |
| GB201810636D0 (en) * | 2018-06-28 | 2018-08-15 | Microsoft Technology Licensing Llc | Dynamic characterisation of synthetic genetic circuits in living cells |
| WO2020005628A1 (en) * | 2018-06-28 | 2020-01-02 | Microsoft Technology Licensing, Llc | Dynamic characterization of synthetic genetic circuits in living cells |
| US11393555B1 (en) * | 2018-09-06 | 2022-07-19 | X Development Llc | Dynamic coordinating framework for model cell simulations |
| GB201900742D0 (en) | 2019-01-18 | 2019-03-06 | Microsoft Technology Licensing Llc | Modelling ordinary differential equations using a variational auto encoder |
| CN110656121B (en) * | 2019-10-29 | 2022-04-29 | 江南大学 | Method for regulating and controlling cell size of escherichia coli |
| US20220036975A1 (en) * | 2020-07-29 | 2022-02-03 | X Development Llc | Kinematic modeling of biochemical pathways |
| CN112562782B (en) * | 2020-12-16 | 2024-02-09 | 中国科学院深圳先进技术研究院 | Construction method of synthetic gene loop model |
| US11797274B2 (en) * | 2021-06-22 | 2023-10-24 | Altered State Machine Limited | Interoperable composite data units for use in distributed computing execution environments |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010025961A2 (en) * | 2008-09-03 | 2010-03-11 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin | Computer implemented model of biological networks |
| EP2465946B1 (en) * | 2009-06-08 | 2016-10-05 | Korea Research Institute of Bioscience and Biotechnology | Method for screening and quantifying various enzyme activities using a genetic enzyme screening system |
| WO2011066539A2 (en) * | 2009-11-30 | 2011-06-03 | Trustees Of Boston University | Biological analog-to-digital and digital-to-analog converter switches |
| US20130191098A1 (en) * | 2010-06-02 | 2013-07-25 | Board Of Regents Of The University Of Texas System | Methods and systems for simulations of complex biological networks using gene expression indexing in computational models |
| WO2014015196A2 (en) * | 2012-07-18 | 2014-01-23 | The Board Of Trustees Of The Leland Stanford Junior University | Techniques for predicting phenotype from genotype based on a whole cell computational model |
| WO2014093852A1 (en) * | 2012-12-13 | 2014-06-19 | Massachusetts Institute Of Technology | Recombinase-based logic and memory systems |
| US20140180660A1 (en) * | 2012-12-14 | 2014-06-26 | Life Technologies Holdings Pte Limited | Methods and systems for in silico design |
-
2015
- 2015-06-19 SG SG11201610126RA patent/SG11201610126RA/en unknown
- 2015-06-19 US US15/321,739 patent/US20170147742A1/en not_active Abandoned
- 2015-06-19 CN CN201580035077.5A patent/CN106663146A/en active Pending
- 2015-06-19 EP EP15811355.5A patent/EP3161697A4/en not_active Withdrawn
- 2015-06-19 WO PCT/SG2015/050169 patent/WO2015199614A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| US20170147742A1 (en) | 2017-05-25 |
| EP3161697A1 (en) | 2017-05-03 |
| WO2015199614A1 (en) | 2015-12-30 |
| EP3161697A4 (en) | 2018-03-14 |
| CN106663146A (en) | 2017-05-10 |
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