SG11201607368XA - Vaccine delivery systems using yeast cell wall particles - Google Patents
Vaccine delivery systems using yeast cell wall particlesInfo
- Publication number
- SG11201607368XA SG11201607368XA SG11201607368XA SG11201607368XA SG11201607368XA SG 11201607368X A SG11201607368X A SG 11201607368XA SG 11201607368X A SG11201607368X A SG 11201607368XA SG 11201607368X A SG11201607368X A SG 11201607368XA SG 11201607368X A SG11201607368X A SG 11201607368XA
- Authority
- SG
- Singapore
- Prior art keywords
- cell wall
- delivery systems
- yeast cell
- vaccine delivery
- wall particles
- Prior art date
Links
- 239000002245 particle Substances 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 210000005253 yeast cell Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4614—Monocytes; Macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464402—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464499—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Botany (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461948503P | 2014-03-05 | 2014-03-05 | |
| US201462060124P | 2014-10-06 | 2014-10-06 | |
| PCT/US2015/018728 WO2015134606A1 (en) | 2014-03-05 | 2015-03-04 | Vaccine delivery systems using yeast cell wall particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201607368XA true SG11201607368XA (en) | 2016-10-28 |
Family
ID=54055837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201607368XA SG11201607368XA (en) | 2014-03-05 | 2015-03-04 | Vaccine delivery systems using yeast cell wall particles |
Country Status (9)
| Country | Link |
|---|---|
| US (6) | US10166195B2 (de) |
| EP (2) | EP3113759B1 (de) |
| JP (3) | JP6797022B2 (de) |
| KR (1) | KR102060858B1 (de) |
| CN (1) | CN106456532B (de) |
| AU (3) | AU2015227226B2 (de) |
| CA (2) | CA2941633C (de) |
| SG (1) | SG11201607368XA (de) |
| WO (1) | WO2015134606A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3113759B1 (de) * | 2014-03-05 | 2021-05-12 | Orbis Health Solutions LLC | Impfstoffabgabesysteme mit hefezellwandpartikeln |
| WO2015187966A1 (en) | 2014-06-04 | 2015-12-10 | Aurasense Therapeutics, Llc | Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications |
| AU2016304853C1 (en) * | 2015-08-11 | 2023-03-16 | Orbis Health Solutions Llc | Bacterial and viral vaccine strategy |
| CN107233298B (zh) * | 2016-03-28 | 2021-01-22 | 复旦大学 | 一种促进蛋白多肽药物口服吸收的酵母细胞壁微粒制剂 |
| CN113143977B (zh) * | 2021-04-16 | 2022-04-05 | 苏州大学 | 酵母细胞壁纳米颗粒及其制备方法与应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4454110A (en) | 1982-05-24 | 1984-06-12 | Forsyth Dental Infirmary For Children | Self-gelling liquid composition for topical application in the oral cavity |
| US4563351A (en) | 1983-08-01 | 1986-01-07 | Forsyth Dental Infirmary For Children | Self-gelling therapeutic compositions for topical application |
| US5032401A (en) | 1989-06-15 | 1991-07-16 | Alpha Beta Technology | Glucan drug delivery system and adjuvant |
| US5340740A (en) | 1992-05-15 | 1994-08-23 | North Carolina State University | Method of producing an avian embryonic stem cell culture and the avian embryonic stem cell culture produced by the process |
| JP3272891B2 (ja) | 1994-11-22 | 2002-04-08 | カネボウ株式会社 | 入浴剤 |
| WO1999030629A1 (en) | 1997-12-17 | 1999-06-24 | Hemodynamics, Inc. | Sealing media for surgery and wound closure |
| US20050158856A1 (en) | 1999-04-20 | 2005-07-21 | Edelson Richard L. | Methods for producing functional antigen presenting dendritic cells using biodegradable microparticles for delivery of antigenic materials |
| US6342203B2 (en) | 1999-10-27 | 2002-01-29 | Dakota Dental Development, Inc. | Compositions for dentistry comprising an oil, to repair, restore, adhere to, or protect the surface of a tooth |
| AU2002225681A1 (en) * | 2000-11-15 | 2002-05-27 | Globe Immune, Inc. | Yeast-dentritic cell vaccines and uses thereof |
| DE60213948T2 (de) | 2001-01-18 | 2007-03-08 | Newcastle University Ventures Ltd. | Biosensor mit kovalent gebundenen membranüberspannenden proteinen |
| ES2598109T3 (es) | 2001-09-06 | 2017-01-25 | Northwest Biotherapeutics, Inc. | Composiciones y métodos para la activación linfocitaria de células dendríticas monocíticas y células T para generar una respuesta Th-1 |
| WO2004014320A2 (en) | 2002-08-13 | 2004-02-19 | Biopolymer Engineering, Inc. | Methods of using beta glucan as a radioprotective agent |
| US20060165700A1 (en) | 2002-09-04 | 2006-07-27 | Ostroff Gary R | Cancer therapy using whole glucan particles and antibodies |
| CN1939335A (zh) * | 2002-09-04 | 2007-04-04 | 路易斯维尔大学研究基金会 | 使用β葡聚糖和抗体治疗癌性的方法 |
| US7943179B2 (en) | 2003-09-23 | 2011-05-17 | Massachusetts Institute Of Technology | pH triggerable polymeric particles |
| EP1753529B1 (de) | 2004-05-20 | 2013-08-14 | Eden Research Plc | Zusammensetzungen, enthaltend ein eine terpenkomponente verkapselndes hohles glucanteilchen oder zellwandteilchen und verfahren zur herstellung und verwendung davon |
| US8007814B2 (en) | 2004-06-16 | 2011-08-30 | University Of Massachusetts | Therapy for lysosomal enzyme deficiencies |
| US7740861B2 (en) * | 2004-06-16 | 2010-06-22 | University Of Massachusetts | Drug delivery product and methods |
| BRPI0516356A (pt) | 2004-10-18 | 2008-09-02 | Globeimmune Inc | terapia à base de levedura para infecções crÈnicas da hepatite c |
| US20060140983A1 (en) | 2004-10-25 | 2006-06-29 | Baylor Research Institute | Dendritic cells loaded with heat shocked melanoma cell bodies |
| JP5489462B2 (ja) | 2005-10-24 | 2014-05-14 | ユニバーシティ オブ マサチューセッツ | 骨病状の遺伝子治療のための組成物およびそれらの使用法 |
| KR101446580B1 (ko) | 2005-11-30 | 2014-10-02 | 에덴 리서치 피엘씨 | 테르펜-함유 조성물 및 이들을 제조하고 사용하는 방법 |
| CN101336291A (zh) | 2005-12-08 | 2008-12-31 | 西北生物治疗药物公司 | 用于诱导未成熟单核细胞的树突细胞的激活的组合物和方法 |
| US7736642B2 (en) | 2006-02-02 | 2010-06-15 | Globeimmune, Inc. | Yeast-based vaccine for inducing an immune response |
| US20080167268A1 (en) | 2006-09-01 | 2008-07-10 | Jun Yan | Particulate beta-glucan compositions for regulating dendritic cells |
| US20100111985A1 (en) | 2007-04-25 | 2010-05-06 | Orbis Health Solutions, Llc | Vaccine compositions and methods of use |
| US8389485B2 (en) | 2007-10-29 | 2013-03-05 | University Of Massachusetts | Encapsulated nanoparticles for nucleic acid delivery |
| JP5690143B2 (ja) | 2008-02-13 | 2015-03-25 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 持続的細胞プログラミング装置 |
| US8728465B2 (en) | 2008-06-17 | 2014-05-20 | Cedars-Sinai Medical Center | Use of toll-like receptor ligands as adjuvants to vaccination therapy for brain tumors |
| WO2011053331A1 (en) | 2009-11-02 | 2011-05-05 | Orbis Health Solutions Llc | Vaccine compositions and methods of use |
| BR112012017306A2 (pt) | 2010-01-12 | 2015-09-15 | Purdue Research Foundation | materiais e métodos para produção de membrana bioinorgânicas que não ocorrem naturalmente associadas e direcionadas à superfície celular |
| WO2011131472A1 (en) | 2010-04-22 | 2011-10-27 | Institut Gustave Roussy | Compounds and uses thereof to induce an immunogenic cancer cell death in a subject |
| US9242857B2 (en) * | 2010-08-14 | 2016-01-26 | University Of Massachusetts | Yeast cell wall particles for receptor-targeted nanoparticle delivery |
| EP2651520A2 (de) | 2010-12-13 | 2013-10-23 | Colgate-Palmolive Company | Orale zusammensetzungen |
| US8926994B2 (en) | 2011-12-07 | 2015-01-06 | The Methodist Hospital Research Institute | Mesoporous silicon particles for the presentation of tumor antigens and adjuvant for anti-cancer immunity |
| US9744193B2 (en) | 2012-09-06 | 2017-08-29 | Orbis Health Solutions Llc | Tumor lysate loaded particles |
| WO2014093454A1 (en) | 2012-12-12 | 2014-06-19 | Orbis Health Solutions, Llc | Compositions and methods for tissue regeneration |
| PH12013000256A1 (en) | 2013-08-30 | 2015-03-09 | Anacleto M Argayosa | Oral vaccine |
| EP3113759B1 (de) * | 2014-03-05 | 2021-05-12 | Orbis Health Solutions LLC | Impfstoffabgabesysteme mit hefezellwandpartikeln |
| US20180228885A1 (en) | 2016-03-04 | 2018-08-16 | Orbis Health Solutions Llc | Bacterial and viral vaccine strategy |
-
2015
- 2015-03-04 EP EP15758254.5A patent/EP3113759B1/de active Active
- 2015-03-04 KR KR1020167027182A patent/KR102060858B1/ko active IP Right Grant
- 2015-03-04 JP JP2016555517A patent/JP6797022B2/ja active Active
- 2015-03-04 WO PCT/US2015/018728 patent/WO2015134606A1/en active Application Filing
- 2015-03-04 CA CA2941633A patent/CA2941633C/en active Active
- 2015-03-04 AU AU2015227226A patent/AU2015227226B2/en active Active
- 2015-03-04 US US15/123,479 patent/US10166195B2/en active Active
- 2015-03-04 EP EP21173240.9A patent/EP3932392A1/de not_active Withdrawn
- 2015-03-04 CN CN201580022772.8A patent/CN106456532B/zh active Active
- 2015-03-04 SG SG11201607368XA patent/SG11201607368XA/en unknown
- 2015-03-04 CA CA3099413A patent/CA3099413A1/en active Pending
-
2016
- 2016-08-31 US US15/252,999 patent/US20170007688A1/en not_active Abandoned
-
2018
- 2018-01-05 AU AU2018200092A patent/AU2018200092B2/en not_active Ceased
- 2018-12-20 US US16/227,468 patent/US10675249B2/en active Active
-
2019
- 2019-07-05 JP JP2019125837A patent/JP6914996B2/ja active Active
- 2019-11-06 US US16/676,395 patent/US11826476B2/en active Active
-
2020
- 2020-05-20 AU AU2020203274A patent/AU2020203274A1/en not_active Abandoned
- 2020-06-05 US US16/893,986 patent/US11179343B2/en active Active
-
2021
- 2021-07-14 JP JP2021116027A patent/JP7311560B2/ja active Active
- 2021-11-22 US US17/532,656 patent/US11759429B2/en active Active
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