SG11201606118SA - Nme variant species expression and suppression - Google Patents

Nme variant species expression and suppression

Info

Publication number
SG11201606118SA
SG11201606118SA SG11201606118SA SG11201606118SA SG11201606118SA SG 11201606118S A SG11201606118S A SG 11201606118SA SG 11201606118S A SG11201606118S A SG 11201606118SA SG 11201606118S A SG11201606118S A SG 11201606118SA SG 11201606118S A SG11201606118S A SG 11201606118SA
Authority
SG
Singapore
Prior art keywords
suppression
variant species
species expression
nme
nme variant
Prior art date
Application number
SG11201606118SA
Other languages
English (en)
Inventor
Cynthia Bamdad
Original Assignee
Minerva Biotechnologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2012/060684 external-priority patent/WO2013059373A2/en
Application filed by Minerva Biotechnologies Corp filed Critical Minerva Biotechnologies Corp
Publication of SG11201606118SA publication Critical patent/SG11201606118SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG11201606118SA 2012-07-24 2013-07-24 Nme variant species expression and suppression SG11201606118SA (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201261675292P 2012-07-24 2012-07-24
US201261677442P 2012-07-30 2012-07-30
US201261679021P 2012-08-02 2012-08-02
US201261683155P 2012-08-14 2012-08-14
US201261684654P 2012-08-17 2012-08-17
US201261693712P 2012-08-27 2012-08-27
PCT/US2012/060684 WO2013059373A2 (en) 2011-10-17 2012-10-17 Media for stem cell proliferation and induction
PCT/US2013/051899 WO2014018679A2 (en) 2012-07-24 2013-07-24 Nme variant species expression and suppression

Publications (1)

Publication Number Publication Date
SG11201606118SA true SG11201606118SA (en) 2016-08-30

Family

ID=49997968

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201606118SA SG11201606118SA (en) 2012-07-24 2013-07-24 Nme variant species expression and suppression
SG10201700593YA SG10201700593YA (en) 2012-07-24 2013-07-24 Nme variant species expression and suppression

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201700593YA SG10201700593YA (en) 2012-07-24 2013-07-24 Nme variant species expression and suppression

Country Status (9)

Country Link
US (2) US20150203823A1 (enrdf_load_stackoverflow)
EP (2) EP4206318A1 (enrdf_load_stackoverflow)
JP (3) JP6546087B2 (enrdf_load_stackoverflow)
CN (2) CN104995518A (enrdf_load_stackoverflow)
AU (2) AU2013295811A1 (enrdf_load_stackoverflow)
CA (1) CA2880010A1 (enrdf_load_stackoverflow)
IL (1) IL236901B (enrdf_load_stackoverflow)
SG (2) SG11201606118SA (enrdf_load_stackoverflow)
WO (1) WO2014018679A2 (enrdf_load_stackoverflow)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2686418A4 (en) 2011-03-17 2015-04-22 Minerva Biotechnologies Corp PROCESS FOR OBTAINING PLURIPOTENT STEM CELLS
AU2012326137B2 (en) 2011-10-17 2018-11-29 Minerva Biotechnologies Corporation Media for stem cell proliferation and induction
EP4233536A3 (en) * 2013-08-12 2023-10-25 Minerva Biotechnologies Corporation Method for enhancing tumor growth
EP3129476B1 (en) 2014-04-07 2022-01-05 Minerva Biotechnologies Corporation Anti-nme antibody
WO2016130726A1 (en) * 2015-02-10 2016-08-18 Minerva Biotechnologies Corporation Humanized anti-muc1* antibodies
CN109081863A (zh) * 2018-08-01 2018-12-25 西北民族大学 抗癌活性物质放线菌素fgr的分离鉴定方法
EP3920693A4 (en) 2019-02-04 2022-10-05 Minerva Biotechnologies Corporation ANTI-NME ANTIBODIES AND METHOD FOR TREATING CANCER OR CANCER METASTASIS
CN116367857A (zh) 2020-06-08 2023-06-30 米纳瓦生物技术公司 抗nme抗体及治疗癌症或癌症转移的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2459583A1 (en) * 2001-09-05 2003-03-13 Minerva Biotechnologies Corporation Compositions and methods of treatment of cancer
EP1375661A1 (en) * 2002-06-17 2004-01-02 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam The role of the N-myc - nm23H1/nm23H2 - cdc42 pathway in proliferation, differentiation and treatment of cancer
CN101273060A (zh) * 2005-06-24 2008-09-24 美国政府（由卫生和人类服务部、国立卫生研究院的部长所代表） 通过靶向肿瘤坏死因子受体的前配体装配域(plad)来缓解炎性关节炎
JP2008099662A (ja) * 2006-09-22 2008-05-01 Institute Of Physical & Chemical Research 幹細胞の培養方法
WO2008067065A2 (en) * 2006-10-19 2008-06-05 Shiv Srivastava Methods, kits, and systems for diagnosing and prognosing prostate cancer using secreted biomarkers
WO2008070171A2 (en) * 2006-12-06 2008-06-12 Minerva Biotechnologies Corp. Method for identifying and manipulating cells
WO2009012173A2 (en) 2007-07-13 2009-01-22 Dharmacon, Inc. Enhanced biotherapeutic production using inhibitory rna
CN102272290B (zh) * 2008-10-09 2018-08-14 米纳瓦生物技术公司 用于在细胞中诱导多能性的方法
KR20170075023A (ko) * 2009-06-11 2017-06-30 미네르바 바이오테크놀로지 코포레이션 줄기 세포 및 전구 세포를 배양하는 방법
EP2582399A4 (en) * 2010-06-16 2015-04-15 Minerva Biotechnologies Corp NEW PROGRAMMING OF CANCER CELLS
JP6748430B2 (ja) * 2012-07-13 2020-09-02 ミネルバ バイオテクノロジーズ コーポレーション より未分化状態への細胞の誘導方法

Also Published As

Publication number Publication date
CN111849874A (zh) 2020-10-30
WO2014018679A2 (en) 2014-01-30
EP2877586A2 (en) 2015-06-03
AU2013295811A1 (en) 2015-03-12
CN104995518A (zh) 2015-10-21
IL236901B (en) 2021-03-25
AU2019203098A1 (en) 2019-05-23
JP2021192614A (ja) 2021-12-23
US20150203823A1 (en) 2015-07-23
WO2014018679A3 (en) 2015-05-07
CA2880010A1 (en) 2014-01-30
IL236901A0 (en) 2015-03-31
AU2019203098B2 (en) 2021-04-08
JP2019141100A (ja) 2019-08-29
US20230049461A1 (en) 2023-02-16
JP2015529454A (ja) 2015-10-08
JP7386210B2 (ja) 2023-11-24
EP2877586A4 (en) 2016-02-17
SG10201700593YA (en) 2017-03-30
JP6546087B2 (ja) 2019-07-17
EP4206318A1 (en) 2023-07-05

Similar Documents

Publication Publication Date Title
IL235826A0 (en) Diazaspirocycloalkane and azaspirocycloalkane
EP2973542A4 (en) CONTEXT-SENSITIVE HANDLING OF INTERRUPTIONS
ZA201408594B (en) Xylitol-based anti-mucosal compositions and related methods and compositions
GB201318361D0 (en) Content protection
IL236901A0 (en) Expression of variable strains of nme and repression
GB201223022D0 (en) Natural language processing
GB201208548D0 (en) Compound and method
GB201216649D0 (en) Agents and methods
EP2806872A4 (en) BENDAMUSTIN COMPOSITIONS AND RELATED METHODS
IL233605A0 (en) Compounds and methods for the treatment of Candida and Aspergillus fungi
IL219244A0 (en) Splitting of user-lists
ZA201405393B (en) Aryloxyacetamide compound and pesticide
GB201315350D0 (en) Methods and compositions
GB201315347D0 (en) Methods and compositions
GB201210398D0 (en) Crop enhancement
IL236154A0 (en) compound and method
GB201319388D0 (en) Rope protector
GB201213778D0 (en) Process and dressng
GB201207907D0 (en) Treatment of depression
GB2506242B (en) Pillowrap - pillow protector
SMT201700322T1 (it) Composizione dermoprotettiva e dermoequilibrante
GB201222736D0 (en) Composition and process
GB201219700D0 (en) Language buddy
GB201212715D0 (en) Treatment of fungal infections
GB201222541D0 (en) Kiddibidet and pottibidet