SG11201505944QA - PPARγ AGONISTS FOR TREATMENT OF MULTIPLE SCLEROSIS - Google Patents

PPARγ AGONISTS FOR TREATMENT OF MULTIPLE SCLEROSIS

Info

Publication number
SG11201505944QA
SG11201505944QA SG11201505944QA SG11201505944QA SG11201505944QA SG 11201505944Q A SG11201505944Q A SG 11201505944QA SG 11201505944Q A SG11201505944Q A SG 11201505944QA SG 11201505944Q A SG11201505944Q A SG 11201505944QA SG 11201505944Q A SG11201505944Q A SG 11201505944QA
Authority
SG
Singapore
Prior art keywords
treatment
multiple sclerosis
pparγ agonists
pparγ
agonists
Prior art date
Application number
SG11201505944QA
Other languages
English (en)
Inventor
David Weinstein
Original Assignee
Intekrin Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intekrin Therapeutics Inc filed Critical Intekrin Therapeutics Inc
Publication of SG11201505944QA publication Critical patent/SG11201505944QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG11201505944QA 2013-01-30 2014-01-23 PPARγ AGONISTS FOR TREATMENT OF MULTIPLE SCLEROSIS SG11201505944QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361758641P 2013-01-30 2013-01-30
PCT/US2014/012656 WO2014120538A1 (en) 2013-01-30 2014-01-23 PPARγ AGONISTS FOR TREATMENT OF MULTIPLE SCLEROSIS

Publications (1)

Publication Number Publication Date
SG11201505944QA true SG11201505944QA (en) 2015-08-28

Family

ID=51223587

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201505944QA SG11201505944QA (en) 2013-01-30 2014-01-23 PPARγ AGONISTS FOR TREATMENT OF MULTIPLE SCLEROSIS
SG10201805896SA SG10201805896SA (en) 2013-01-30 2014-01-23 PPARγ AGONISTS FOR TREATMENT OF MULTIPLE SCLEROSIS

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201805896SA SG10201805896SA (en) 2013-01-30 2014-01-23 PPARγ AGONISTS FOR TREATMENT OF MULTIPLE SCLEROSIS

Country Status (15)

Country Link
US (3) US9061020B2 (ko)
EP (1) EP2950798B1 (ko)
JP (3) JP5989921B2 (ko)
KR (2) KR102056756B1 (ko)
CN (1) CN105228622B (ko)
AU (1) AU2014212740B2 (ko)
BR (1) BR112015018048A2 (ko)
CA (1) CA2899187C (ko)
EA (2) EA201792096A3 (ko)
ES (1) ES2883141T3 (ko)
HK (1) HK1218510A1 (ko)
IL (2) IL240051A (ko)
MX (1) MX366765B (ko)
SG (2) SG11201505944QA (ko)
WO (1) WO2014120538A1 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130158077A1 (en) 2011-12-19 2013-06-20 Ares Trading S.A. Pharmaceutical compositions
KR102056756B1 (ko) * 2013-01-30 2019-12-17 인테크린 테라퓨틱스, 아이엔씨. 다발성 경화증의 치료를 위한 PPARγ 작용제
CN107683135A (zh) 2015-03-09 2018-02-09 因特克林医疗有限公司 用于治疗非酒精性脂肪肝疾病和/或脂肪营养不良的方法
US20190167660A1 (en) * 2016-08-18 2019-06-06 Intekrin Therapeutics, Inc. PPAR-gamma AGONIST FOR TREATMENT OF BONE DISORDERS
US20210379049A1 (en) * 2016-08-18 2021-12-09 Coherus Biosciences, Inc PPAR-gamma AGONIST FOR TREATMENT OF BLOOD CANCERS
KR20190064583A (ko) * 2016-09-13 2019-06-10 인테크린 테라퓨틱스, 아이엔씨. Chs-131로 다발성 경화증의 치료
SG11201909046XA (en) * 2017-04-03 2019-10-30 Coherus Biosciences Inc PPARγ AGONIST FOR TREATMENT OF PROGRESSIVE SUPRANUCLEAR PALSY
EA201992364A1 (ru) * 2018-04-02 2020-03-23 Кохерус Байосайенсис Инк. АГОНИСТ PPARγ ДЛЯ ЛЕЧЕНИЯ ПРОГРЕССИРУЮЩЕГО НАДЪЯДЕРНОГО ПАРАЛИЧА
US20220387393A1 (en) * 2019-11-06 2022-12-08 Board Of Regents, The University Of Texas System Methods for the treatment of dysmyelinating/demyelinating diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030171399A1 (en) 2000-06-28 2003-09-11 Tularik Inc. Quinolinyl and benzothiazolyl modulators
US7223761B2 (en) * 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
US20050250820A1 (en) * 2004-03-08 2005-11-10 Amgen Inc. Therapeutic modulation of PPARgamma activity
EP2175845A2 (en) * 2007-07-11 2010-04-21 Cardoz AB New combination for use in the treatment of inflammatory disorders
EP2242747A1 (de) * 2008-02-07 2010-10-27 Sanofi-Aventis Substituierte imidazolidin-2,4-dione, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
US20100087481A1 (en) * 2008-10-03 2010-04-08 Lee Kathleen M Oral pharmaceutical formulations for antidiabetic compounds
WO2012040082A2 (en) * 2010-09-21 2012-03-29 Intekrin Therapeutics, Inc. Antidiabetic solid pharmaceutical compositions
KR102056756B1 (ko) * 2013-01-30 2019-12-17 인테크린 테라퓨틱스, 아이엔씨. 다발성 경화증의 치료를 위한 PPARγ 작용제

Also Published As

Publication number Publication date
EP2950798A1 (en) 2015-12-09
ES2883141T3 (es) 2021-12-07
AU2014212740B2 (en) 2015-12-24
CA2899187C (en) 2016-06-07
US9061020B2 (en) 2015-06-23
JP2018039817A (ja) 2018-03-15
CN105228622A (zh) 2016-01-06
US9539249B2 (en) 2017-01-10
KR20160137653A (ko) 2016-11-30
JP2017014251A (ja) 2017-01-19
KR20150133182A (ko) 2015-11-27
EA201792096A2 (ru) 2018-01-31
JP2016506956A (ja) 2016-03-07
US20170143687A1 (en) 2017-05-25
MX366765B (es) 2019-07-23
KR102056756B1 (ko) 2019-12-17
BR112015018048A2 (pt) 2020-01-28
EP2950798A4 (en) 2016-06-29
HK1218510A1 (zh) 2017-02-24
IL240051A0 (en) 2015-09-24
EP2950798B1 (en) 2021-05-12
MX2015009818A (es) 2015-10-29
CN105228622B (zh) 2017-09-22
EA029216B1 (ru) 2018-02-28
IL240051A (en) 2016-11-30
US9867816B2 (en) 2018-01-16
US20140213612A1 (en) 2014-07-31
WO2014120538A1 (en) 2014-08-07
US20150238478A1 (en) 2015-08-27
CA2899187A1 (en) 2014-08-07
JP6466540B2 (ja) 2019-02-06
IL248594B (en) 2021-10-31
EA201591399A1 (ru) 2015-12-30
JP6224189B2 (ja) 2017-11-01
EA201792096A3 (ru) 2018-05-31
JP5989921B2 (ja) 2016-09-07
SG10201805896SA (en) 2018-08-30
AU2014212740A1 (en) 2015-08-13
IL248594A0 (en) 2016-12-29

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