SG11201504455PA - Rapid, low-sample-volume cholesterol and triglyceride assays - Google Patents

Rapid, low-sample-volume cholesterol and triglyceride assays

Info

Publication number
SG11201504455PA
SG11201504455PA SG11201504455PA SG11201504455PA SG11201504455PA SG 11201504455P A SG11201504455P A SG 11201504455PA SG 11201504455P A SG11201504455P A SG 11201504455PA SG 11201504455P A SG11201504455P A SG 11201504455PA SG 11201504455P A SG11201504455P A SG 11201504455PA
Authority
SG
Singapore
Prior art keywords
rapid
sample
low
cholesterol
volume
Prior art date
Application number
SG11201504455PA
Inventor
Douglas Matje
Paul Patel
Elizabeth A Holmes
Original Assignee
Theranos Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theranos Inc filed Critical Theranos Inc
Publication of SG11201504455PA publication Critical patent/SG11201504455PA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/60Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/61Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving triglycerides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00Chromogens for determinations of oxidoreductase enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00Chromogens for determinations of oxidoreductase enzymes
    • C12Q2326/90Developer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00Chromogens for determinations of oxidoreductase enzymes
    • C12Q2326/90Developer
    • C12Q2326/964-Amino-antipyrine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00Reactions characterised by treatment of reaction samples
    • C12Q2523/10Characterised by chemical treatment
    • C12Q2523/115Characterised by chemical treatment oxidising agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/902Oxidoreductases (1.)
    • G01N2333/904Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/902Oxidoreductases (1.)
    • G01N2333/908Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/916Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • G01N2333/918Carboxylic ester hydrolases (3.1.1)
    • G01N2333/92Triglyceride splitting, e.g. by means of lipase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
SG11201504455PA 2012-12-10 2013-12-10 Rapid, low-sample-volume cholesterol and triglyceride assays SG11201504455PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261735424P 2012-12-10 2012-12-10
PCT/US2013/074211 WO2014093399A1 (en) 2012-12-10 2013-12-10 Rapid, low-sample-volume cholesterol and triglyceride assays

Publications (1)

Publication Number Publication Date
SG11201504455PA true SG11201504455PA (en) 2015-07-30

Family

ID=50931352

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201504455PA SG11201504455PA (en) 2012-12-10 2013-12-10 Rapid, low-sample-volume cholesterol and triglyceride assays

Country Status (13)

Country Link
US (4) US9051599B2 (en)
EP (2) EP2929046B1 (en)
JP (4) JP2016505250A (en)
KR (1) KR20150094710A (en)
CN (2) CN104995310B (en)
AU (1) AU2013359422A1 (en)
CA (1) CA2891944A1 (en)
ES (1) ES2729794T3 (en)
HK (1) HK1216763A1 (en)
IL (1) IL239229A (en)
MX (1) MX364956B (en)
SG (1) SG11201504455PA (en)
WO (1) WO2014093399A1 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201606120XA (en) 2007-10-02 2016-09-29 Theranos Inc Modular Point-Of-Care Devices And Uses Thereof
CN106248582B (en) 2011-01-21 2020-10-20 拉布拉多诊断有限责任公司 System and method for maximizing sample usage
US9268915B2 (en) 2011-09-25 2016-02-23 Theranos, Inc. Systems and methods for diagnosis or treatment
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US9664702B2 (en) 2011-09-25 2017-05-30 Theranos, Inc. Fluid handling apparatus and configurations
US9619627B2 (en) 2011-09-25 2017-04-11 Theranos, Inc. Systems and methods for collecting and transmitting assay results
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US9250229B2 (en) 2011-09-25 2016-02-02 Theranos, Inc. Systems and methods for multi-analysis
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
US9051599B2 (en) 2012-12-10 2015-06-09 Theranos, Inc. Rapid, low-sample-volume cholesterol and triglyceride assays
WO2015035256A2 (en) 2013-09-06 2015-03-12 Theranos, Inc. Devices, systems, methods and kits for receiving a swab
CN111378568A (en) 2013-09-06 2020-07-07 赛拉诺斯知识产权有限责任公司 Systems and methods for detecting infectious diseases
CN104914141B (en) * 2015-01-30 2017-10-17 南京工业大学 A kind of preparation and application of novel low density lipoprotein cholesterol electrochemical immunosensor
CN104865392B (en) * 2015-05-02 2016-09-14 王贤俊 A kind of LDL-C quantitative detecting method
KR101882485B1 (en) 2016-06-30 2018-07-27 강경찬 Method for measuring liver enzyme and lipid
CN106399460B (en) * 2016-09-29 2020-03-17 中国医学科学院北京协和医院 Kit and method for determining triglycerides
CN106367471B (en) * 2016-09-29 2021-12-03 中国医学科学院北京协和医院 Kit and method for determining total cholesterol
CN106950095B (en) * 2017-04-01 2020-01-10 合肥迪安医学检验所有限公司 Method for reducing detection interference of lipemia sample
CN108690869A (en) * 2017-04-05 2018-10-23 广州市伊川生物科技有限公司 A kind of high-density lipoprotein cholesterol detection kit and its detection method
CN108949903B (en) * 2017-05-17 2021-11-16 广州市伊川生物科技有限公司 Triglyceride determination kit and determination method thereof
US10684277B2 (en) * 2017-07-24 2020-06-16 Comsats Institute Of Information Technology Colorimetric filter paper assay for rapid monitoring of cholesterol level
CN111602053B (en) * 2018-01-09 2023-05-09 艾德克斯实验室公司 Method for measuring analytes and/or proteins in biological samples
CN109580511A (en) * 2018-12-06 2019-04-05 潍坊泽成生物技术有限公司 A kind of detection method and detection kit of high-density lipoprotein cholesterol
CN109799356A (en) * 2018-12-28 2019-05-24 上海高踪医疗器械科技有限公司 A kind of kit and method measuring high-density lipoprotein cholesterol
LU101273B1 (en) * 2019-06-21 2020-12-28 Ecole Polytechnique Fed Lausanne Epfl Sensing platform
WO2021023876A1 (en) 2019-08-08 2021-02-11 ObsEva S.A. Gnrh antagonists for the treatment of estrogen-dependent disorders
CN111829991A (en) * 2020-08-04 2020-10-27 东北大学 beta-CD-based reflective optical fiber cholesterol sensor and preparation method thereof
CN113008807A (en) * 2021-03-10 2021-06-22 谱天(天津)生物科技有限公司 Method for determining extremely-low-density lipoprotein subcomponent component distribution
WO2023049473A1 (en) * 2021-09-27 2023-03-30 Icahn School Of Medicine At Mount Sinai System and method to determine the concentration of lipoprotein (a) cholesterol
CN113897413A (en) * 2021-10-12 2022-01-07 广州达安基因股份有限公司 In-vitro diagnostic reagent preservative and application thereof

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US9051599B2 (en) 2012-12-10 2015-06-09 Theranos, Inc. Rapid, low-sample-volume cholesterol and triglyceride assays

Also Published As

Publication number Publication date
US9546394B2 (en) 2017-01-17
KR20150094710A (en) 2015-08-19
JP2016505250A (en) 2016-02-25
JP2019054811A (en) 2019-04-11
EP2929046A4 (en) 2016-06-29
CN104995310B (en) 2020-07-28
WO2014093399A1 (en) 2014-06-19
IL239229A0 (en) 2015-07-30
US10392650B2 (en) 2019-08-27
MX364956B (en) 2019-05-15
US20140170688A1 (en) 2014-06-19
US20160024554A1 (en) 2016-01-28
CN104995310A (en) 2015-10-21
JP2023015207A (en) 2023-01-31
ES2729794T3 (en) 2019-11-06
US9051599B2 (en) 2015-06-09
US11268130B2 (en) 2022-03-08
US20200063185A1 (en) 2020-02-27
HK1216763A1 (en) 2016-12-02
IL239229A (en) 2017-02-28
MX2015007131A (en) 2015-10-14
AU2013359422A1 (en) 2015-06-04
EP2929046B1 (en) 2019-03-20
CA2891944A1 (en) 2014-06-19
JP2021006060A (en) 2021-01-21
EP3561068A1 (en) 2019-10-30
EP2929046A1 (en) 2015-10-14
US20170175168A1 (en) 2017-06-22
CN111748605A (en) 2020-10-09

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