SG11201501510SA - Combinations of sglt2 inhibitors and antihypertensive drugs - Google Patents

Combinations of sglt2 inhibitors and antihypertensive drugs

Info

Publication number
SG11201501510SA
SG11201501510SA SG11201501510SA SG11201501510SA SG11201501510SA SG 11201501510S A SG11201501510S A SG 11201501510SA SG 11201501510S A SG11201501510S A SG 11201501510SA SG 11201501510S A SG11201501510S A SG 11201501510SA SG 11201501510S A SG11201501510S A SG 11201501510SA
Authority
SG
Singapore
Prior art keywords
combinations
antihypertensive drugs
sglt2 inhibitors
sglt2
inhibitors
Prior art date
Application number
SG11201501510SA
Other languages
English (en)
Inventor
Naoki Kojima
J Richard Roman
Noriyuki Miyata
Teisuke Takahashi
Hideki Tomoike
Takuya Takeda
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of SG11201501510SA publication Critical patent/SG11201501510SA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201501510SA 2012-08-30 2013-08-30 Combinations of sglt2 inhibitors and antihypertensive drugs SG11201501510SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261695016P 2012-08-30 2012-08-30
PCT/JP2013/073300 WO2014034842A1 (ja) 2012-08-30 2013-08-30 Ｓｇｌｔ２阻害薬と抗高血圧薬との組み合わせ

Publications (1)

Publication Number Publication Date
SG11201501510SA true SG11201501510SA (en) 2015-04-29

Family

ID=50183647

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201501510SA SG11201501510SA (en) 2012-08-30 2013-08-30 Combinations of sglt2 inhibitors and antihypertensive drugs

Country Status (17)

Country Link
US (1) US9320727B2 (OSRAM)
EP (1) EP2891499A4 (OSRAM)
JP (2) JP6198013B2 (OSRAM)
KR (1) KR20150046125A (OSRAM)
CN (1) CN104780942A (OSRAM)
AU (1) AU2013309904A1 (OSRAM)
BR (1) BR112015004012A2 (OSRAM)
CA (1) CA2883118A1 (OSRAM)
HK (1) HK1208621A1 (OSRAM)
IN (1) IN2015DN01975A (OSRAM)
MX (1) MX2015002572A (OSRAM)
PH (1) PH12015500434B1 (OSRAM)
RU (1) RU2015110979A (OSRAM)
SG (1) SG11201501510SA (OSRAM)
TW (1) TW201414472A (OSRAM)
WO (1) WO2014034842A1 (OSRAM)
ZA (1) ZA201502009B (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101943382B1 (ko) * 2017-09-19 2019-01-29 오토텔릭바이오 주식회사 Sglt-2 저해제 및 안지오텐신 수용체 차단제를 포함하는 의약 조성물
CN109806397A (zh) * 2017-11-20 2019-05-28 江苏恒瑞医药股份有限公司 Sglt2抑制剂与arb联合在制备治疗高血压等疾病的药物中的用途
KR102131359B1 (ko) * 2018-09-07 2020-07-07 오토텔릭바이오 주식회사 안정성이 향상된 의약 조성물
JP7659783B2 (ja) 2019-09-13 2025-04-10 国立大学法人富山大学 急性心不全における体液貯留改善薬
CA3180674A1 (en) * 2020-04-22 2021-10-28 Bayer Aktiengesellschaft Combination of finerenone and a sglt2 inhibitor for the treatment and/or prevention of cardiovascular and/or renal diseases
CN116490178A (zh) * 2020-08-17 2023-07-25 北京睿创康泰医药研究院有限公司 Sglt-2抑制剂与血管紧张素受体阻滞剂的组合物及用途
WO2022176981A1 (ja) * 2021-02-19 2022-08-25 大正製薬株式会社 経口フィルム製剤
WO2023075461A1 (ko) * 2021-10-27 2023-05-04 지용하 안지오텐신 수용체 차단제 및 sglt2 억제제를 포함하는 복합 조성물
KR20240099023A (ko) * 2022-12-20 2024-06-28 주식회사 티에치팜 나트륨 포도당 운반체-2 저해제 및 안지오텐신 ⅱ 수용체 차단제를 함유하는 심혈관 질환 예방 또는 치료용 약학적 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515117B2 (en) * 1999-10-12 2003-02-04 Bristol-Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
PH12000002657B1 (en) 1999-10-12 2006-02-21 Bristol Myers Squibb Co C-aryl glucoside SGLT2 inhibitors
DE102004048388A1 (de) 2004-10-01 2006-04-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg D-Pyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
TW200637839A (en) 2005-01-07 2006-11-01 Taisho Pharmaceutical Co Ltd 1-thio-d-glucitol derivatives
JP5194588B2 (ja) * 2006-07-06 2013-05-08 大正製薬株式会社 １−チオ−ｄ−グルシトール誘導体を有効成分として含有する糖尿病の予防又は治療剤
TW200904405A (en) * 2007-03-22 2009-02-01 Bristol Myers Squibb Co Pharmaceutical formulations containing an SGLT2 inhibitor
EP2147008A2 (en) * 2007-05-18 2010-01-27 Bristol-Myers Squibb Company Crystal structures of sglt2 inhibitors and processes for preparing same
WO2010048358A2 (en) * 2008-10-22 2010-04-29 Auspex Pharmaceutical, Inc. Ethoxyphenylmethyl inhibitors of sglt2
PT2601949E (pt) 2009-04-16 2014-11-12 Taisho Pharmaceutical Co Ltd Composições farmacêuticas com (1s)-1,5-anidro-1-[5-(4- etoxibenzil)-2-metoxi-4-metilfenil]-1-tio-d-glucitol e um secretagogo de insulina
CN102639125A (zh) * 2009-05-27 2012-08-15 百时美施贵宝公司 使用sglt2抑制剂及其组合物在对先前用其它抗糖尿病药进行的治疗具有耐受的患者中治疗ii型糖尿病的方法

Also Published As

Publication number Publication date
ZA201502009B (en) 2016-07-27
EP2891499A4 (en) 2016-02-24
US9320727B2 (en) 2016-04-26
PH12015500434B1 (en) 2022-04-22
CA2883118A1 (en) 2014-03-06
EP2891499A1 (en) 2015-07-08
HK1208621A1 (en) 2016-03-11
WO2014034842A1 (ja) 2014-03-06
AU2013309904A1 (en) 2015-03-19
BR112015004012A2 (pt) 2017-07-04
JP6198013B2 (ja) 2017-09-20
MX2015002572A (es) 2015-06-05
JP6358515B2 (ja) 2018-07-18
US20150320721A1 (en) 2015-11-12
IN2015DN01975A (OSRAM) 2015-08-14
CN104780942A (zh) 2015-07-15
TW201414472A (zh) 2014-04-16
JPWO2014034842A1 (ja) 2016-08-08
JP2017186353A (ja) 2017-10-12
RU2015110979A (ru) 2016-10-20
PH12015500434A1 (en) 2015-04-20
KR20150046125A (ko) 2015-04-29

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