SG11201408083YA - Compositions and methods for enhancing mobilization and proliferation of blastomere-like stem cells - Google Patents

Compositions and methods for enhancing mobilization and proliferation of blastomere-like stem cells

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Publication number
SG11201408083YA
SG11201408083YA SG11201408083YA SG11201408083YA SG11201408083YA SG 11201408083Y A SG11201408083Y A SG 11201408083YA SG 11201408083Y A SG11201408083Y A SG 11201408083YA SG 11201408083Y A SG11201408083Y A SG 11201408083YA SG 11201408083Y A SG11201408083Y A SG 11201408083YA
Authority
SG
Singapore
Prior art keywords
international
stem cells
california
blastomere
proliferation
Prior art date
Application number
SG11201408083YA
Inventor
Christian Drapeau
Original Assignee
Stemtech International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemtech International Inc filed Critical Stemtech International Inc
Publication of SG11201408083YA publication Critical patent/SG11201408083YA/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/748Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20Milk; Whey; Colostrum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
    • A61K36/068Cordyceps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/72Undefined extracts from bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 16 January 2014 (16.01.2014) WIPOIPCT (10) International Publication Number WO 2014/011752 A1 (51) International Patent Classification: C12N 5/0789 (2010.01) (21) International Application Number: PCT/US2013/049897 (22) International Filing Date: 10 July 2013 (10.07.2013) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 61/670,253 11 July 2012 (11.07.2012) US (71) Applicant: STEMTECH INTERNATIONAL, INC. [US/US]; 151 Calle Iglesia, San Clemente, California 92672 (US). (72) Inventor: DRAPEAU, Christian; 151 Calle Iglesia, San Clemente, California 92672 (US). (74) Agents: CHEN, Stephen, W. et al.; Nixon Peabody LLP, Gas Company Tower, 555 West Fifth Street, 46th Floor, Los Angeles, California 90013 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (54) Title: COMPOSITIONS AND METHODS FOR ENHANCING MOBILIZATION AND PROLIFERATION OF BLASTOMERE-LIKE STEM CELLS (57) Abstract: The present invention provides a method of using mobilization agents to enhance stem cell trafficking in a subject, including very small embryonic-like (VSEL) stem cells. In one embodiment, a blended composition of algae, fruits, mush­ rooms, microorganisms, maternal fluids, and extracts thereof are used to promote traffick- | UHf i w ing of stem cells, resulting in migration of the stem cells to specific sites of maintenance and repair within tissues and/or organs.
SG11201408083YA 2012-07-11 2013-07-10 Compositions and methods for enhancing mobilization and proliferation of blastomere-like stem cells SG11201408083YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261670253P 2012-07-11 2012-07-11
PCT/US2013/049897 WO2014011752A1 (en) 2012-07-11 2013-07-10 Compositions and methods for enhancing mobilization and proliferation of blastomere-like stem cells

Publications (1)

Publication Number Publication Date
SG11201408083YA true SG11201408083YA (en) 2015-01-29

Family

ID=49916528

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201408083YA SG11201408083YA (en) 2012-07-11 2013-07-10 Compositions and methods for enhancing mobilization and proliferation of blastomere-like stem cells

Country Status (16)

Country Link
US (1) US20150182574A1 (en)
EP (1) EP2872623A4 (en)
JP (1) JP2015522076A (en)
KR (1) KR20150029654A (en)
AU (1) AU2013290276A1 (en)
BR (1) BR112015000099A2 (en)
CA (1) CA2874483A1 (en)
EC (1) ECSP15001113A (en)
HK (1) HK1210501A1 (en)
IN (1) IN2014MN02401A (en)
MX (1) MX2015000318A (en)
PH (1) PH12014502711A1 (en)
RU (1) RU2015104535A (en)
SG (1) SG11201408083YA (en)
WO (1) WO2014011752A1 (en)
ZA (1) ZA201408758B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX344304B (en) 2010-06-28 2016-12-13 Stemtech Int Inc Methods and compositions for enhancing stem cell mobilization.
KR20140091674A (en) 2011-11-18 2014-07-22 스템테크 인터내셔널, 인크. Use of foti to enhance stem cell mobilization and proliferation
JP6495174B2 (en) 2012-12-06 2019-04-03 ステムバイオス テクノロジーズ,インコーポレイテッド LGR5 + somatic stem cells
CN105687245A (en) * 2014-12-13 2016-06-22 干细胞生物科技公司 Method of preparing injection solution
KR101884872B1 (en) 2017-03-31 2018-08-02 (주)세원물산 Friction stir spot welding method and welding device therefor
CN108588009A (en) * 2018-05-10 2018-09-28 广州四叶草健康科技有限公司 A method of it detaches and activates the minimum embryonic-like stem cell of human peripheral
CN109717346B (en) * 2019-03-08 2022-02-01 中国科学院西北高原生物研究所 Method for preserving cordyceps sinensis by irradiation method
CN111658631A (en) * 2020-06-11 2020-09-15 广东盛普生命科技有限公司 Application of gallic acid and its derivatives and structural analogs in preparing anti-coronavirus medicine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6814961B1 (en) * 2001-05-14 2004-11-09 Gitte S. Jensen Method for enhancing stem cell trafficking
US20050042314A1 (en) * 2003-08-22 2005-02-24 National Yang-Ming University Extracts of Polygonum multiflorum Thunb., and preparation process and uses of the same
EP1789540B9 (en) * 2004-09-03 2012-02-22 Moraga Biotechnology Inc. Non-embryonic totipotent blastomer-like stem cells and methods therefor
KR101489728B1 (en) * 2005-06-24 2015-02-04 데저트 레이크 테크놀로지스 Purified component of blue-green algae and method of use
MX344304B (en) * 2010-06-28 2016-12-13 Stemtech Int Inc Methods and compositions for enhancing stem cell mobilization.
RU2013140543A (en) * 2011-01-31 2015-03-10 ЛЭЙСИ Джон 152/18-19 Силом Рд.Бангкок 10500 Тайланд PLURIPOTENT STEM CELLS AND METHOD OF STIMULATION AND ISOLATION OF NON-EMBRYONAL PLURIPOTENT STEM CELLS FROM MAMMAL BLOOD AND APPLICATION OF DILATED PLURIPOTENT STEM CELLS
KR20140091674A (en) * 2011-11-18 2014-07-22 스템테크 인터내셔널, 인크. Use of foti to enhance stem cell mobilization and proliferation

Also Published As

Publication number Publication date
ECSP15001113A (en) 2018-07-31
WO2014011752A1 (en) 2014-01-16
MX2015000318A (en) 2015-04-14
CA2874483A1 (en) 2014-01-16
PH12014502711A1 (en) 2015-02-02
ZA201408758B (en) 2016-03-30
EP2872623A1 (en) 2015-05-20
BR112015000099A2 (en) 2017-06-27
IN2014MN02401A (en) 2015-08-21
HK1210501A1 (en) 2016-04-22
JP2015522076A (en) 2015-08-03
EP2872623A4 (en) 2016-08-10
AU2013290276A1 (en) 2014-12-18
US20150182574A1 (en) 2015-07-02
RU2015104535A (en) 2016-08-27
KR20150029654A (en) 2015-03-18

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