SG10202110774QA - Recombinant host cell with altered membrane lipid composition - Google Patents

Recombinant host cell with altered membrane lipid composition

Info

Publication number
SG10202110774QA
SG10202110774QA SG10202110774QA SG10202110774QA SG10202110774QA SG 10202110774Q A SG10202110774Q A SG 10202110774QA SG 10202110774Q A SG10202110774Q A SG 10202110774QA SG 10202110774Q A SG10202110774Q A SG 10202110774QA SG 10202110774Q A SG10202110774Q A SG 10202110774QA
Authority
SG
Singapore
Prior art keywords
host cell
recombinant host
lipid composition
membrane lipid
altered membrane
Prior art date
Application number
SG10202110774QA
Inventor
Karlheinz Grillitsch
Guenther Daum
Andreas Grutsch
Original Assignee
Boehringer Ingelheim Rcv Gmbh
Validogen Gmbh
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Rcv Gmbh, Validogen Gmbh, Lonza Ag filed Critical Boehringer Ingelheim Rcv Gmbh
Publication of SG10202110774QA publication Critical patent/SG10202110774QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG10202110774QA 2017-03-29 2018-03-28 Recombinant host cell with altered membrane lipid composition SG10202110774QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17163588 2017-03-29

Publications (1)

Publication Number Publication Date
SG10202110774QA true SG10202110774QA (en) 2021-11-29

Family

ID=58464254

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202110774QA SG10202110774QA (en) 2017-03-29 2018-03-28 Recombinant host cell with altered membrane lipid composition
SG11201908079S SG11201908079SA (en) 2017-03-29 2018-03-28 Recombinant host cell with altered membrane lipid composition

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201908079S SG11201908079SA (en) 2017-03-29 2018-03-28 Recombinant host cell with altered membrane lipid composition

Country Status (9)

Country Link
US (1) US11479798B2 (en)
EP (1) EP3601575A1 (en)
JP (1) JP7189145B2 (en)
KR (1) KR102692583B1 (en)
CN (1) CN110612352A (en)
AU (1) AU2018241920B2 (en)
CA (1) CA3056920A1 (en)
SG (2) SG10202110774QA (en)
WO (1) WO2018178126A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110951635A (en) * 2019-12-17 2020-04-03 江南大学 Method for regulating saccharomyces cerevisiae cell membrane phospholipid to resist salt stress
CN112430611A (en) * 2020-11-30 2021-03-02 华南理工大学 Optimized zearalenone degrading enzyme ZHD-P encoding gene, recombinant thallus, surface display system and application
CN115160420B (en) * 2022-06-24 2023-06-02 西南大学 Pichia glabra SCP (SCP) secretion protein and application thereof
WO2024141641A2 (en) * 2022-12-30 2024-07-04 Biotalys NV Secretion signals
CN117777276B (en) * 2024-02-23 2024-06-04 北京国科星联科技有限公司 Method for promoting secretion expression of human lactoferrin by kluyveromyces marxianus

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EP0388186A1 (en) 1989-03-17 1990-09-19 E.I. Du Pont De Nemours And Company External regulation of gene expression
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IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE4343591A1 (en) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Process for the evolutionary design and synthesis of functional polymers based on shape elements and shape codes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
DE4440118C1 (en) 1994-11-11 1995-11-09 Forschungszentrum Juelich Gmbh Gene expression in coryneform bacteria regulating DNA
GB9515941D0 (en) 1995-08-03 1995-10-04 Zeneca Ltd DNA constructs
GB9516241D0 (en) 1995-08-08 1995-10-11 Zeneca Ltd Dna constructs
JPH10229891A (en) 1997-02-20 1998-09-02 Mitsubishi Rayon Co Ltd Production of malonic acid derivative
WO1998046774A1 (en) * 1997-04-11 1998-10-22 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal rna encoding domain, particularly with kluyveromyces
ATE375388T1 (en) 2001-07-27 2007-10-15 Us Gov Health & Human Serv SYSTEMS FOR SITE-DIRECTED IN VIVO MUTAGENesis USING OLIGONUCLEOTIDES
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AU2008241061A1 (en) 2007-04-20 2008-10-30 Polymun Scientific Immunbiologische Forschung Gmbh Yeast expression systems
US20130137140A1 (en) * 2010-06-17 2013-05-30 Universiteit Gent Increased protein expression through increased membrane formation
WO2012004226A1 (en) * 2010-07-05 2012-01-12 Universität Für Bodenkultur Wien Production cell line
WO2012071439A1 (en) * 2010-11-22 2012-05-31 The Regents Of The University Of California Host cells and methods for producing diacid compounds
JP6295512B2 (en) 2012-03-15 2018-03-20 株式会社豊田中央研究所 Method for producing foreign gene expression product in yeast, expression regulator in yeast and use thereof
KR20150069015A (en) * 2012-10-15 2015-06-22 게노마티카 인코포레이티드 Microorganisms and methods for production of specific length fatty alcohols and related compounds
WO2015158800A1 (en) 2014-04-17 2015-10-22 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell for expressing proteins of interest
US10865416B2 (en) * 2014-04-17 2020-12-15 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell engineered to overexpress helper proteins
KR102311681B1 (en) * 2015-07-28 2021-10-12 삼성전자주식회사 Yeast cell resistant to acid, method for producing an organic acid using the same, and method for producing the same

Also Published As

Publication number Publication date
US11479798B2 (en) 2022-10-25
CN110612352A (en) 2019-12-24
WO2018178126A1 (en) 2018-10-04
JP7189145B2 (en) 2022-12-13
US20210301313A1 (en) 2021-09-30
JP2020515261A (en) 2020-05-28
AU2018241920B2 (en) 2022-04-21
US20230257792A1 (en) 2023-08-17
CA3056920A1 (en) 2018-10-04
EP3601575A1 (en) 2020-02-05
KR20190140939A (en) 2019-12-20
SG11201908079SA (en) 2019-10-30
KR102692583B1 (en) 2024-08-06
AU2018241920A1 (en) 2019-09-19

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