SG10202110774QA - Recombinant host cell with altered membrane lipid composition - Google Patents
Recombinant host cell with altered membrane lipid compositionInfo
- Publication number
- SG10202110774QA SG10202110774QA SG10202110774QA SG10202110774QA SG10202110774QA SG 10202110774Q A SG10202110774Q A SG 10202110774QA SG 10202110774Q A SG10202110774Q A SG 10202110774QA SG 10202110774Q A SG10202110774Q A SG 10202110774QA SG 10202110774Q A SG10202110774Q A SG 10202110774QA
- Authority
- SG
- Singapore
- Prior art keywords
- host cell
- recombinant host
- lipid composition
- membrane lipid
- altered membrane
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17163588 | 2017-03-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10202110774QA true SG10202110774QA (en) | 2021-11-29 |
Family
ID=58464254
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202110774QA SG10202110774QA (en) | 2017-03-29 | 2018-03-28 | Recombinant host cell with altered membrane lipid composition |
SG11201908079S SG11201908079SA (en) | 2017-03-29 | 2018-03-28 | Recombinant host cell with altered membrane lipid composition |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201908079S SG11201908079SA (en) | 2017-03-29 | 2018-03-28 | Recombinant host cell with altered membrane lipid composition |
Country Status (9)
Country | Link |
---|---|
US (1) | US11479798B2 (en) |
EP (1) | EP3601575A1 (en) |
JP (1) | JP7189145B2 (en) |
KR (1) | KR102692583B1 (en) |
CN (1) | CN110612352A (en) |
AU (1) | AU2018241920B2 (en) |
CA (1) | CA3056920A1 (en) |
SG (2) | SG10202110774QA (en) |
WO (1) | WO2018178126A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110951635A (en) * | 2019-12-17 | 2020-04-03 | 江南大学 | Method for regulating saccharomyces cerevisiae cell membrane phospholipid to resist salt stress |
CN112430611A (en) * | 2020-11-30 | 2021-03-02 | 华南理工大学 | Optimized zearalenone degrading enzyme ZHD-P encoding gene, recombinant thallus, surface display system and application |
CN115160420B (en) * | 2022-06-24 | 2023-06-02 | 西南大学 | Pichia glabra SCP (SCP) secretion protein and application thereof |
WO2024141641A2 (en) * | 2022-12-30 | 2024-07-04 | Biotalys NV | Secretion signals |
CN117777276B (en) * | 2024-02-23 | 2024-06-04 | 北京国科星联科技有限公司 | Method for promoting secretion expression of human lactoferrin by kluyveromyces marxianus |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4546082A (en) | 1982-06-17 | 1985-10-08 | Regents Of The Univ. Of California | E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins |
US4760025A (en) | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
US4601893A (en) | 1984-02-08 | 1986-07-22 | Pfizer Inc. | Laminate device for controlled and prolonged release of substances to an ambient environment and method of use |
GB8726953D0 (en) | 1987-11-18 | 1987-12-23 | Delta Biotechnology Ltd | Yeast expression system |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
EP0388186A1 (en) | 1989-03-17 | 1990-09-19 | E.I. Du Pont De Nemours And Company | External regulation of gene expression |
DE4027453A1 (en) | 1990-08-30 | 1992-03-05 | Degussa | NEW PLASMIDES FROM CORYNEBACTERIUM GLUTAMICUM AND DERIVED PLASMIDE VECTORS |
IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
DE4343591A1 (en) | 1993-12-21 | 1995-06-22 | Evotec Biosystems Gmbh | Process for the evolutionary design and synthesis of functional polymers based on shape elements and shape codes |
US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
DE4440118C1 (en) | 1994-11-11 | 1995-11-09 | Forschungszentrum Juelich Gmbh | Gene expression in coryneform bacteria regulating DNA |
GB9515941D0 (en) | 1995-08-03 | 1995-10-04 | Zeneca Ltd | DNA constructs |
GB9516241D0 (en) | 1995-08-08 | 1995-10-11 | Zeneca Ltd | Dna constructs |
JPH10229891A (en) | 1997-02-20 | 1998-09-02 | Mitsubishi Rayon Co Ltd | Production of malonic acid derivative |
WO1998046774A1 (en) * | 1997-04-11 | 1998-10-22 | Dsm N.V. | Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal rna encoding domain, particularly with kluyveromyces |
ATE375388T1 (en) | 2001-07-27 | 2007-10-15 | Us Gov Health & Human Serv | SYSTEMS FOR SITE-DIRECTED IN VIVO MUTAGENesis USING OLIGONUCLEOTIDES |
DE10219203A1 (en) * | 2002-04-29 | 2003-11-13 | Basf Plant Science Gmbh | Process for the production of polyunsaturated fatty acids in plants |
US7470532B2 (en) * | 2005-10-19 | 2008-12-30 | E.I. Du Pont De Nemours And Company | Mortierella alpina C16/18 fatty acid elongase |
CN101605887B (en) * | 2006-05-16 | 2012-09-05 | 协和发酵麒麟株式会社 | High secretion production method of protein |
TWI419902B (en) * | 2007-03-02 | 2013-12-21 | 百靈佳殷格翰製藥公司 | Improvement of protein production |
AU2008241061A1 (en) | 2007-04-20 | 2008-10-30 | Polymun Scientific Immunbiologische Forschung Gmbh | Yeast expression systems |
US20130137140A1 (en) * | 2010-06-17 | 2013-05-30 | Universiteit Gent | Increased protein expression through increased membrane formation |
WO2012004226A1 (en) * | 2010-07-05 | 2012-01-12 | Universität Für Bodenkultur Wien | Production cell line |
WO2012071439A1 (en) * | 2010-11-22 | 2012-05-31 | The Regents Of The University Of California | Host cells and methods for producing diacid compounds |
JP6295512B2 (en) | 2012-03-15 | 2018-03-20 | 株式会社豊田中央研究所 | Method for producing foreign gene expression product in yeast, expression regulator in yeast and use thereof |
KR20150069015A (en) * | 2012-10-15 | 2015-06-22 | 게노마티카 인코포레이티드 | Microorganisms and methods for production of specific length fatty alcohols and related compounds |
WO2015158800A1 (en) | 2014-04-17 | 2015-10-22 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Recombinant host cell for expressing proteins of interest |
US10865416B2 (en) * | 2014-04-17 | 2020-12-15 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Recombinant host cell engineered to overexpress helper proteins |
KR102311681B1 (en) * | 2015-07-28 | 2021-10-12 | 삼성전자주식회사 | Yeast cell resistant to acid, method for producing an organic acid using the same, and method for producing the same |
-
2018
- 2018-03-28 CN CN201880028304.5A patent/CN110612352A/en active Pending
- 2018-03-28 CA CA3056920A patent/CA3056920A1/en active Pending
- 2018-03-28 EP EP18722403.5A patent/EP3601575A1/en active Pending
- 2018-03-28 JP JP2019553357A patent/JP7189145B2/en active Active
- 2018-03-28 KR KR1020197031992A patent/KR102692583B1/en active IP Right Grant
- 2018-03-28 US US16/499,072 patent/US11479798B2/en active Active
- 2018-03-28 SG SG10202110774QA patent/SG10202110774QA/en unknown
- 2018-03-28 SG SG11201908079S patent/SG11201908079SA/en unknown
- 2018-03-28 WO PCT/EP2018/057853 patent/WO2018178126A1/en unknown
- 2018-03-28 AU AU2018241920A patent/AU2018241920B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US11479798B2 (en) | 2022-10-25 |
CN110612352A (en) | 2019-12-24 |
WO2018178126A1 (en) | 2018-10-04 |
JP7189145B2 (en) | 2022-12-13 |
US20210301313A1 (en) | 2021-09-30 |
JP2020515261A (en) | 2020-05-28 |
AU2018241920B2 (en) | 2022-04-21 |
US20230257792A1 (en) | 2023-08-17 |
CA3056920A1 (en) | 2018-10-04 |
EP3601575A1 (en) | 2020-02-05 |
KR20190140939A (en) | 2019-12-20 |
SG11201908079SA (en) | 2019-10-30 |
KR102692583B1 (en) | 2024-08-06 |
AU2018241920A1 (en) | 2019-09-19 |
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