SG10201801943SA - Integrated continuous isolation of fluid streams from sterile process vessels - Google Patents

Integrated continuous isolation of fluid streams from sterile process vessels

Info

Publication number
SG10201801943SA
SG10201801943SA SG10201801943SA SG10201801943SA SG10201801943SA SG 10201801943S A SG10201801943S A SG 10201801943SA SG 10201801943S A SG10201801943S A SG 10201801943SA SG 10201801943S A SG10201801943S A SG 10201801943SA SG 10201801943S A SG10201801943S A SG 10201801943SA
Authority
SG
Singapore
Prior art keywords
fluid streams
integrated continuous
process vessels
sterile process
continuous isolation
Prior art date
Application number
SG10201801943SA
Inventor
Robert Snow
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of SG10201801943SA publication Critical patent/SG10201801943SA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/12Apparatus for enzymology or microbiology with sterilisation, filtration or dialysis means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/26Inoculator or sampler
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/58Reaction vessels connected in series or in parallel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04Filters; Permeable or porous membranes or plates, e.g. dialysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10Perfusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/26Conditioning fluids entering or exiting the reaction vessel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02Filters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/06Means for testing the completeness of the sterilization
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Peptides Or Proteins (AREA)
SG10201801943SA 2014-10-24 2015-10-20 Integrated continuous isolation of fluid streams from sterile process vessels SG10201801943SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462068181P 2014-10-24 2014-10-24

Publications (1)

Publication Number Publication Date
SG10201801943SA true SG10201801943SA (en) 2018-05-30

Family

ID=54478962

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201801943SA SG10201801943SA (en) 2014-10-24 2015-10-20 Integrated continuous isolation of fluid streams from sterile process vessels
SG11201703265XA SG11201703265XA (en) 2014-10-24 2015-10-20 Integrated continuous isolation of fluid streams from sterile process vessels

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201703265XA SG11201703265XA (en) 2014-10-24 2015-10-20 Integrated continuous isolation of fluid streams from sterile process vessels

Country Status (17)

Country Link
US (3) US20160115438A1 (en)
EP (1) EP3209765B1 (en)
JP (2) JP6672287B2 (en)
KR (1) KR102465762B1 (en)
CN (2) CN107109322B (en)
AU (1) AU2015336130B2 (en)
BR (1) BR112017008252B1 (en)
CA (1) CA2965478C (en)
DK (1) DK3209765T3 (en)
ES (1) ES2931455T3 (en)
HU (1) HUE060385T2 (en)
IL (1) IL251819B (en)
MX (1) MX2017005348A (en)
RU (1) RU2713126C2 (en)
SG (2) SG10201801943SA (en)
TW (2) TWI691342B (en)
WO (1) WO2016064846A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107109322B (en) * 2014-10-24 2021-04-06 建新公司 Integrated continuous separation of fluid streams from a sterilization process vessel
WO2019086324A1 (en) 2017-10-31 2019-05-09 Ge Healthcare Bio-Sciences Corp. A flexible bag
TWI747743B (en) * 2021-02-22 2021-11-21 全淨然興業股份有限公司 Amino acid enzyme automatic generation and activation equipment
CN114947113A (en) * 2021-02-24 2022-08-30 游家源 Method and equipment for preparing plant amino acid enzyme
EP4339274A1 (en) * 2022-09-13 2024-03-20 Sartorius Stedim Biotech GmbH Method for operating a bioprocess installation for production of a bioproduct
JP7422925B1 (en) 2023-07-19 2024-01-26 佐竹マルチミクス株式会社 Bioreactor culture method and bioreactor sterilization device

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Also Published As

Publication number Publication date
AU2015336130A1 (en) 2017-06-08
CA2965478A1 (en) 2016-04-28
EP3209765B1 (en) 2022-09-07
TW201625318A (en) 2016-07-16
JP2017531444A (en) 2017-10-26
RU2020102925A3 (en) 2022-02-16
CA2965478C (en) 2023-03-14
JP6994526B2 (en) 2022-02-21
RU2017115655A (en) 2018-11-26
BR112017008252B1 (en) 2022-03-03
DK3209765T3 (en) 2022-11-28
CN113105992B (en) 2024-05-14
RU2020102925A (en) 2021-07-26
US20160115438A1 (en) 2016-04-28
KR20170072932A (en) 2017-06-27
HUE060385T2 (en) 2023-02-28
WO2016064846A1 (en) 2016-04-28
ES2931455T3 (en) 2022-12-29
TWI740417B (en) 2021-09-21
IL251819B (en) 2020-11-30
IL251819A0 (en) 2017-06-29
US11920120B2 (en) 2024-03-05
MX2017005348A (en) 2017-07-28
CN107109322B (en) 2021-04-06
JP2020103307A (en) 2020-07-09
RU2017115655A3 (en) 2019-08-07
SG11201703265XA (en) 2017-05-30
CN113105992A (en) 2021-07-13
US20210002601A1 (en) 2021-01-07
KR102465762B1 (en) 2022-11-09
BR112017008252A2 (en) 2017-12-26
AU2015336130B2 (en) 2020-07-09
EP3209765A1 (en) 2017-08-30
TWI691342B (en) 2020-04-21
TW202026016A (en) 2020-07-16
US20220081669A1 (en) 2022-03-17
JP6672287B2 (en) 2020-03-25
CN107109322A (en) 2017-08-29
RU2713126C2 (en) 2020-02-03

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