SG10201801905WA - A combination therapy for a stable and long term engraftment - Google Patents

A combination therapy for a stable and long term engraftment

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Publication number
SG10201801905WA
SG10201801905WA SG10201801905WA SG10201801905WA SG10201801905WA SG 10201801905W A SG10201801905W A SG 10201801905WA SG 10201801905W A SG10201801905W A SG 10201801905WA SG 10201801905W A SG10201801905W A SG 10201801905WA SG 10201801905W A SG10201801905W A SG 10201801905WA
Authority
SG
Singapore
Prior art keywords
stable
long term
combination therapy
term engraftment
engraftment
Prior art date
Application number
SG10201801905WA
Inventor
Yair Reisner
Esther Bachar-Lustig
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of SG10201801905WA publication Critical patent/SG10201801905WA/en

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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
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    • A61K2039/507—Comprising a combination of two or more separate antibodies
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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  • General Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Public Health (AREA)
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  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
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  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
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SG10201801905WA 2011-12-22 2012-12-20 A combination therapy for a stable and long term engraftment SG10201801905WA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161578917P 2011-12-22 2011-12-22

Publications (1)

Publication Number Publication Date
SG10201801905WA true SG10201801905WA (en) 2018-04-27

Family

ID=48669650

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201801905WA SG10201801905WA (en) 2011-12-22 2012-12-20 A combination therapy for a stable and long term engraftment
SG11201403456UA SG11201403456UA (en) 2011-12-22 2012-12-20 A combination therapy for a stable and long term engraftment using specific protocols for t/b cell depletion
SG11201403459XA SG11201403459XA (en) 2011-12-22 2012-12-20 A combination therapy for a stable and long term engraftment

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG11201403456UA SG11201403456UA (en) 2011-12-22 2012-12-20 A combination therapy for a stable and long term engraftment using specific protocols for t/b cell depletion
SG11201403459XA SG11201403459XA (en) 2011-12-22 2012-12-20 A combination therapy for a stable and long term engraftment

Country Status (17)

Country Link
US (5) US10369172B2 (en)
EP (2) EP2793914B1 (en)
JP (3) JP2015504047A (en)
KR (2) KR20140105848A (en)
CN (2) CN104093314A (en)
AU (3) AU2012355990B2 (en)
BR (2) BR112014015959A8 (en)
CA (2) CA2859953A1 (en)
DK (2) DK2793914T3 (en)
ES (2) ES2811529T3 (en)
HK (2) HK1202775A1 (en)
IN (2) IN2014MN01468A (en)
MX (2) MX2014007648A (en)
RU (2) RU2657758C2 (en)
SG (3) SG10201801905WA (en)
WO (2) WO2013093920A2 (en)
ZA (2) ZA201405071B (en)

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CN104105493A (en) 2011-12-08 2014-10-15 耶达研究及发展有限公司 Mammalian fetal pulmonary cells and therapeutic use of same
RU2657758C2 (en) * 2011-12-22 2018-06-15 Иеда Рисеч Энд Девелопмент Ко. Лтд. Combination therapy for stable and long-term transplant engraftment
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WO2016203477A1 (en) 2015-06-18 2016-12-22 Yeda Research And Development Co. Ltd. Conditioning protocols and use of same for tissue regeneration
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CN109475581A (en) * 2016-05-22 2019-03-15 耶达研究及发展有限公司 In order to transplant and inducing tolerance and use pneumonocyte method
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WO2020061180A1 (en) * 2018-09-18 2020-03-26 Medeor Therapeutics, Inc. Cellular compositions derived from deceased donors to promote graft tolerance and manufacture and uses thereof
CN112930187A (en) * 2018-09-27 2021-06-08 弗斯弗加姆股份有限公司 Methods and compositions for the expansion and use of allogeneic gamma/delta-T cells
CN109781987B (en) * 2019-01-09 2022-04-26 暨南大学 Application of terminal effector T cell subset in preparation of kit for auxiliary evaluation of aplastic anemia disease degree
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RU2723164C1 (en) * 2019-10-07 2020-06-09 Федеральное государственное бюджетное учреждение науки "Кировский научно-исследовательский институт гематологии и переливания крови Федерального медико-биологического агентства" Method for calculating the dose of haematopoiesis precursor cells in a leukocytapheresis product by taking into account the change in the integrity of cell membranes during storage
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