SG10201707917UA - Obtaining an improved therapeutic ligand - Google Patents
Obtaining an improved therapeutic ligandInfo
- Publication number
- SG10201707917UA SG10201707917UA SG10201707917UA SG10201707917UA SG10201707917UA SG 10201707917U A SG10201707917U A SG 10201707917UA SG 10201707917U A SG10201707917U A SG 10201707917UA SG 10201707917U A SG10201707917U A SG 10201707917UA SG 10201707917U A SG10201707917U A SG 10201707917UA
- Authority
- SG
- Singapore
- Prior art keywords
- obtaining
- improved therapeutic
- therapeutic ligand
- ligand
- improved
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
- G16B15/30—Drug targeting using structural data; Docking or binding prediction
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/50—Molecular design, e.g. of drugs
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/90—Programming languages; Computing architectures; Database systems; Data warehousing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Computational Biology (AREA)
- General Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Computing Systems (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Organic Chemistry (AREA)
- Databases & Information Systems (AREA)
- Software Systems (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1310544.0A GB201310544D0 (en) | 2013-06-13 | 2013-06-13 | Obtaining an improved therapeutic ligand |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201707917UA true SG10201707917UA (en) | 2017-10-30 |
Family
ID=48914497
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201707917UA SG10201707917UA (en) | 2013-06-13 | 2014-06-13 | Obtaining an improved therapeutic ligand |
| SG11201510084TA SG11201510084TA (en) | 2013-06-13 | 2014-06-13 | Obtaining an improved therapeutic ligand |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201510084TA SG11201510084TA (en) | 2013-06-13 | 2014-06-13 | Obtaining an improved therapeutic ligand |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20160125124A1 (zh) |
| EP (1) | EP3008648B1 (zh) |
| JP (1) | JP6484612B2 (zh) |
| KR (1) | KR20160019504A (zh) |
| CN (1) | CN105308602B (zh) |
| AU (1) | AU2014280055A1 (zh) |
| BR (1) | BR112015031171A2 (zh) |
| CA (1) | CA2914726A1 (zh) |
| CL (1) | CL2015003591A1 (zh) |
| GB (1) | GB201310544D0 (zh) |
| HK (1) | HK1218579A1 (zh) |
| MX (1) | MX2015016822A (zh) |
| RU (1) | RU2016100234A (zh) |
| SG (2) | SG10201707917UA (zh) |
| WO (1) | WO2014198951A2 (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240024520A1 (en) | 2020-03-27 | 2024-01-25 | UCB Biopharma SRL | Autonomous knob domain peptides |
| CN113380320B (zh) * | 2021-07-01 | 2022-03-15 | 中国海洋大学 | 基于阳性化合物残基贡献相似度的分子对接结果筛选方法 |
| CN114530215B (zh) * | 2022-02-18 | 2023-03-28 | 北京有竹居网络技术有限公司 | 设计配体分子的方法和装置 |
| CN115171774A (zh) * | 2022-05-17 | 2022-10-11 | 慧壹科技(上海)有限公司 | 一种抗体/大分子药物的亲和力改造系统和方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5331573A (en) * | 1990-12-14 | 1994-07-19 | Balaji Vitukudi N | Method of design of compounds that mimic conformational features of selected peptides |
| WO1993020525A1 (en) | 1992-03-27 | 1993-10-14 | Akiko Itai | Method of searching the structure of stable biopolymer-ligand molecule composite |
| GB0011818D0 (en) * | 2000-05-16 | 2000-07-05 | Inpharmatica Ltd | Lead molecule generation |
| US20020025535A1 (en) | 2000-06-15 | 2002-02-28 | Diller David J. | Prioritization of combinatorial library screening |
| AU2001279973A1 (en) | 2000-08-21 | 2002-03-04 | Ribotargets Limited | Computer-based modelling of ligand/receptor structures |
| JP2004511803A (ja) * | 2000-10-16 | 2004-04-15 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | バニロイド受容体についての改良リガンド結合アッセイ |
| CN100374456C (zh) * | 2000-12-29 | 2008-03-12 | 萨文特医药公司 | 用于选择性癌症治疗的特异性人抗体 |
| US20030148391A1 (en) * | 2002-01-24 | 2003-08-07 | Salafsky Joshua S. | Method using a nonlinear optical technique for detection of interactions involving a conformational change |
| US20040229290A1 (en) | 2003-05-07 | 2004-11-18 | Duke University | Protein design for receptor-ligand recognition and binding |
| US20060105390A1 (en) * | 2003-10-29 | 2006-05-18 | Yi Zhang | Method of characterizing heterogeneity in receptor-ligand interactions and related method of assay signal histogram transformation |
| JP2005181104A (ja) * | 2003-12-19 | 2005-07-07 | Hitachi Ltd | 高精度ドッキングスコアリング方法 |
| ES2432753T3 (es) | 2005-03-11 | 2013-12-05 | Schrödinger, Llc | Función de puntuación predictiva para estimar la afinidad de unión |
| GB0620729D0 (en) | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
| US20090006040A1 (en) | 2007-05-24 | 2009-01-01 | Peter Hrnciar | Systems and Methods for Representing Protein Binding Sites and Identifying Molecules with Biological Activity |
| EP2216429A4 (en) | 2007-11-12 | 2011-06-15 | In Silico Sciences Inc | SILICO SCREENING SYSTEM AND SILICO SCREENING METHOD |
| GB0807413D0 (en) | 2008-04-23 | 2008-05-28 | Ucb Pharma Sa | Biological products |
| EP2412809B1 (en) * | 2009-03-24 | 2017-08-09 | Kaneka Corporation | Protein having affinity for immunoglobulin, and immunoglobulin-binding affinity ligand |
| US9023876B2 (en) * | 2010-07-08 | 2015-05-05 | Adhaere Pharmaceuticals, Inc. | Compounds and methods for regulating integrins |
| MA34907B1 (fr) | 2011-01-14 | 2014-02-01 | Ucb Pharma Sa | Molécules d'anticorps se liant à il-17a et il-17f |
-
2013
- 2013-06-13 GB GBGB1310544.0A patent/GB201310544D0/en not_active Ceased
-
2014
- 2014-06-13 BR BR112015031171A patent/BR112015031171A2/pt not_active IP Right Cessation
- 2014-06-13 SG SG10201707917UA patent/SG10201707917UA/en unknown
- 2014-06-13 RU RU2016100234A patent/RU2016100234A/ru not_active Application Discontinuation
- 2014-06-13 JP JP2016518523A patent/JP6484612B2/ja active Active
- 2014-06-13 EP EP14729693.3A patent/EP3008648B1/en active Active
- 2014-06-13 AU AU2014280055A patent/AU2014280055A1/en not_active Abandoned
- 2014-06-13 WO PCT/EP2014/062478 patent/WO2014198951A2/en active Application Filing
- 2014-06-13 US US14/897,459 patent/US20160125124A1/en not_active Abandoned
- 2014-06-13 CA CA2914726A patent/CA2914726A1/en not_active Abandoned
- 2014-06-13 KR KR1020167000533A patent/KR20160019504A/ko not_active Application Discontinuation
- 2014-06-13 CN CN201480033334.7A patent/CN105308602B/zh active Active
- 2014-06-13 SG SG11201510084TA patent/SG11201510084TA/en unknown
- 2014-06-13 MX MX2015016822A patent/MX2015016822A/es unknown
-
2015
- 2015-12-10 CL CL2015003591A patent/CL2015003591A1/es unknown
-
2016
- 2016-06-07 HK HK16106512.8A patent/HK1218579A1/zh unknown
-
2020
- 2020-03-18 US US16/823,055 patent/US11942188B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3008648B1 (en) | 2023-05-10 |
| JP2016527481A (ja) | 2016-09-08 |
| SG11201510084TA (en) | 2016-01-28 |
| KR20160019504A (ko) | 2016-02-19 |
| HK1218579A1 (zh) | 2017-02-24 |
| BR112015031171A2 (pt) | 2017-07-25 |
| US20210005277A1 (en) | 2021-01-07 |
| CN105308602A (zh) | 2016-02-03 |
| RU2016100234A (ru) | 2018-02-06 |
| WO2014198951A3 (en) | 2015-08-27 |
| GB201310544D0 (en) | 2013-07-31 |
| RU2016100234A3 (zh) | 2018-03-23 |
| CA2914726A1 (en) | 2014-12-18 |
| US20160125124A1 (en) | 2016-05-05 |
| JP6484612B2 (ja) | 2019-03-13 |
| US11942188B2 (en) | 2024-03-26 |
| CN105308602B (zh) | 2019-09-27 |
| WO2014198951A2 (en) | 2014-12-18 |
| MX2015016822A (es) | 2016-04-13 |
| CL2015003591A1 (es) | 2016-08-05 |
| EP3008648A2 (en) | 2016-04-20 |
| AU2014280055A1 (en) | 2016-01-28 |
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