SG10201502266RA - Boronic acids and esters as inhibitors of fatty amide hydrolase - Google Patents

Boronic acids and esters as inhibitors of fatty amide hydrolase

Info

Publication number
SG10201502266RA
SG10201502266RA SG10201502266RA SG10201502266RA SG10201502266RA SG 10201502266R A SG10201502266R A SG 10201502266RA SG 10201502266R A SG10201502266R A SG 10201502266RA SG 10201502266R A SG10201502266R A SG 10201502266RA SG 10201502266R A SG10201502266R A SG 10201502266RA
Authority
SG
Singapore
Prior art keywords
inhibitors
esters
boronic acids
fatty amide
amide hydrolase
Prior art date
Application number
SG10201502266RA
Inventor
Adams Julian
L Behnke Mark
C Castro Alfredo
A Evans Catherine
Grenier Louis
J Grogan Michael
Tao Liu
A Snyder Daniel
T Tibbitts Thomas
Original Assignee
Infinity Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39323893&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201502266R(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Infinity Pharmaceuticals Inc filed Critical Infinity Pharmaceuticals Inc
Publication of SG10201502266RA publication Critical patent/SG10201502266RA/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
SG10201502266RA 2006-10-10 2007-10-10 Boronic acids and esters as inhibitors of fatty amide hydrolase SG10201502266RA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85052006P 2006-10-10 2006-10-10

Publications (1)

Publication Number Publication Date
SG10201502266RA true SG10201502266RA (en) 2015-05-28

Family

ID=39323893

Family Applications (3)

Application Number Title Priority Date Filing Date
SG2011073830A SG175608A1 (en) 2006-10-10 2007-10-10 Boronic acids and esters as inhibitors of fatty amide hydrolase
SG10201502266RA SG10201502266RA (en) 2006-10-10 2007-10-10 Boronic acids and esters as inhibitors of fatty amide hydrolase
SG10201908757T SG10201908757TA (en) 2006-10-10 2007-10-10 Boronic acids and esters as inhibitors of fatty amide hydrolase

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2011073830A SG175608A1 (en) 2006-10-10 2007-10-10 Boronic acids and esters as inhibitors of fatty amide hydrolase

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201908757T SG10201908757TA (en) 2006-10-10 2007-10-10 Boronic acids and esters as inhibitors of fatty amide hydrolase

Country Status (27)

Country Link
US (6) US7947663B2 (en)
EP (4) EP2404607A1 (en)
JP (2) JP5641600B2 (en)
KR (2) KR20090085623A (en)
CN (2) CN101563089A (en)
AR (1) AR063165A1 (en)
AT (1) ATE524188T1 (en)
AU (1) AU2007322268B2 (en)
BR (1) BRPI0719218A2 (en)
CA (1) CA2666224C (en)
CL (1) CL2007002910A1 (en)
DK (1) DK2073816T3 (en)
ES (1) ES2373697T3 (en)
HK (1) HK1137137A1 (en)
IL (2) IL197932A (en)
JO (1) JO3598B1 (en)
MX (1) MX2009003727A (en)
NO (1) NO342439B1 (en)
NZ (1) NZ576851A (en)
PE (1) PE20081172A1 (en)
PH (1) PH12012500765A1 (en)
PT (1) PT2073816E (en)
RU (1) RU2492174C2 (en)
SG (3) SG175608A1 (en)
TW (1) TWI451870B (en)
UA (1) UA101601C2 (en)
WO (1) WO2008063300A2 (en)

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US9149465B2 (en) 2009-05-18 2015-10-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US8765735B2 (en) 2009-05-18 2014-07-01 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
AR076687A1 (en) * 2009-05-18 2011-06-29 Infinity Pharmaceuticals Inc ISOXAZOLINS AS INHIBITORS OF THE AMIDAHIDROLASA OF FATTY ACIDS AND PHARMACEUTICAL COM-POSITIONS CONTAINING THEM
WO2011085216A2 (en) 2010-01-08 2011-07-14 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating parkinson's disease and restless legs syndrome
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US20130224151A1 (en) 2010-03-31 2013-08-29 United States Of America Use of FAAH Inhibitors for Treating Abdominal, Visceral and Pelvic Pain
US20130079305A1 (en) * 2010-05-31 2013-03-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. 3-substituted vinylboronates and uses thereof
CA2812608C (en) 2010-10-06 2020-07-14 Glaxosmithkline Llc Benzimidazole derivatives as pi3 kinase inhibitors
WO2012112670A1 (en) * 2011-02-16 2012-08-23 Albert Einstein College Of Medicine Of Yeshiva University Novel lipogenic inhibitors and uses thereof
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CN104662028B (en) * 2012-06-25 2017-05-24 托马斯杰弗逊大学 Compositions and methods for treating cancer with aberrant lipogenic signaling
AP3778A (en) * 2012-07-10 2016-08-31 Bayer Pharma AG Method for preparing substituted triazolopyridines
EP2909216B1 (en) * 2012-10-17 2016-12-21 Board of Supervisors of Louisiana State University and Agricultural and Mechanical College Compositions and methods for improving glucose uptake
CA2914521A1 (en) * 2013-06-07 2014-12-11 Bayer Pharma Aktiengesellschaft Substituted triazolopyridines having activity as mps-1 inhibitors
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AU2018230580A1 (en) 2017-03-09 2019-09-19 The Penn State Research Foundation Boron-containing small molecules for inhibiting activity of a receptor-like protein tyrosine phosphatase
CN108409727A (en) * 2017-10-25 2018-08-17 巨德峰 A kind of inhibitors of fatty amide hydrolase and preparation method thereof
WO2019173394A1 (en) 2018-03-05 2019-09-12 Wylder Nation Foundation Compositions and methods for activating signaling through the cb1 cannabinoid receptor for treating and preventing diseases and disorders characterized by abnormal cellular accumulation of sphingolipids such as sphingomyelin
EP3632908A1 (en) * 2018-10-02 2020-04-08 Inventiva Inhibitors of the yap/taz-tead interaction and their use in the treatment of cancer
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EP3917536A4 (en) * 2019-02-01 2022-11-23 The Board of Trustees of the Leland Stanford Junior University Enpp1 inhibitors and methods of modulating immune response
TW202103708A (en) * 2019-04-12 2021-02-01 美商里伯賽恩斯有限責任公司 Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors
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