SG10201403152QA - Determination of coronary artery disease risk - Google Patents

Determination of coronary artery disease risk

Info

Publication number
SG10201403152QA
SG10201403152QA SG10201403152QA SG10201403152QA SG10201403152QA SG 10201403152Q A SG10201403152Q A SG 10201403152QA SG 10201403152Q A SG10201403152Q A SG 10201403152QA SG 10201403152Q A SG10201403152Q A SG 10201403152QA SG 10201403152Q A SG10201403152Q A SG 10201403152QA
Authority
SG
Singapore
Prior art keywords
determination
coronary artery
artery disease
disease risk
risk
Prior art date
Application number
SG10201403152QA
Other languages
English (en)
Inventor
Rosenberg Steven
R Elashoff Michael
Beineke Philip
A Wingrove James
G Tingley Whittemore
E Daniels Susan
Original Assignee
Cardiodx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiodx Inc filed Critical Cardiodx Inc
Publication of SG10201403152QA publication Critical patent/SG10201403152QA/en

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20Supervised data analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30Unsupervised data analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Data Mining & Analysis (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Databases & Information Systems (AREA)
  • Analytical Chemistry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Software Systems (AREA)
  • Evolutionary Computation (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Primary Health Care (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
SG10201403152QA 2009-06-15 2010-06-15 Determination of coronary artery disease risk SG10201403152QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18720309P 2009-06-15 2009-06-15
US24519009P 2009-09-23 2009-09-23

Publications (1)

Publication Number Publication Date
SG10201403152QA true SG10201403152QA (en) 2014-08-28

Family

ID=43356727

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2011090107A SG176692A1 (en) 2009-06-15 2010-06-15 Determination of coronary artery disease risk.
SG10201403152QA SG10201403152QA (en) 2009-06-15 2010-06-15 Determination of coronary artery disease risk

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2011090107A SG176692A1 (en) 2009-06-15 2010-06-15 Determination of coronary artery disease risk.

Country Status (13)

Country Link
US (3) US9122777B2 (de)
EP (1) EP2443449B1 (de)
JP (1) JP2012529914A (de)
KR (1) KR20120046171A (de)
CN (1) CN102803951A (de)
AU (1) AU2010260152A1 (de)
BR (1) BRPI1010693A2 (de)
CA (1) CA2765145A1 (de)
DK (1) DK2443449T3 (de)
EA (1) EA201270020A1 (de)
IL (1) IL216875A0 (de)
SG (2) SG176692A1 (de)
WO (1) WO2010148017A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2443449T3 (en) 2009-06-15 2017-05-15 Cardiodx Inc DETERMINATION OF RISK OF CORONARY ARTERY DISEASE
EP2591357A4 (de) 2010-07-09 2014-01-01 Somalogic Inc Biomarker für lungenkrebs und verwendung
CA2804857C (en) 2010-08-13 2021-07-06 Somalogic, Inc. Pancreatic cancer biomarkers and uses thereof
WO2012094366A1 (en) * 2011-01-06 2012-07-12 Cardiodx, Inc. Circulating mirnas as biomarkers for coronary artery disease
KR102111624B1 (ko) * 2011-09-30 2020-05-18 소마로직, 인크. 심혈관 위험 사건 예측 및 그것의 용도
CN104101715A (zh) * 2014-07-15 2014-10-15 重庆医科大学附属儿童医院 检测dock8蛋白的试剂盒及非诊断目的检测dock8蛋白的方法
WO2016076899A1 (en) * 2014-11-14 2016-05-19 Medidata Solutions, Inc. System and method for determining subject conditions in mobile health clinical trials
ES2836684T3 (es) * 2015-07-31 2021-06-28 Vascular Biogenics Ltd Proteína 2 que contiene el dominio del esperma móvil e inflamación
NZ738875A (en) 2015-07-31 2023-06-30 Vascular Biogenics Ltd Motile sperm domain containing protein 2 and cancer
CA2996191A1 (en) * 2015-09-01 2017-03-09 Cardiodx, Inc. Markers for coronary artery disease and uses thereof
US11056218B2 (en) 2016-05-31 2021-07-06 International Business Machines Corporation Identifying personalized time-varying predictive patterns of risk factors
CN106327476A (zh) * 2016-08-25 2017-01-11 于洋 一种ct图像处理方法及装置
WO2018045079A1 (en) 2016-09-01 2018-03-08 The George Washington University Blood rna biomarkers of coronary artery disease
US10832815B2 (en) 2017-05-18 2020-11-10 International Business Machines Corporation Medical side effects tracking
CN107271681A (zh) * 2017-06-05 2017-10-20 中国人民解放军沈阳军区总医院 血浆s100a12在st段抬高型心肌梗死早期诊断中的应用
CN107238712B (zh) * 2017-06-05 2018-12-28 中国人民解放军沈阳军区总医院 血浆s100a12在st段抬高型心肌梗死预后中的应用
CN107292128A (zh) * 2017-06-27 2017-10-24 湖南农业大学 一种配对互作基因检测方法及预测模型
CN107937521B (zh) * 2017-11-19 2019-01-04 武汉迈特维尔生物科技有限公司 用于检测肾上腺皮质癌的试剂盒
US20210217485A1 (en) * 2018-01-15 2021-07-15 Chang Gung Memorial Hospital, Linkou Method of establishing a coronary artery disease prediction model for screening coronary artery disease
CN111354464B (zh) * 2018-12-24 2024-05-17 深圳先进技术研究院 Cad预测模型建立方法、装置以及电子设备
CN111789949A (zh) * 2019-04-08 2020-10-20 北京昱嘉科技集团有限公司 基于特异性趋化因子受体的阿尔兹海默病治疗靶点
RU2740246C1 (ru) * 2020-03-20 2021-01-12 Жанна Залкуфовна Отарова Способ определения высокого риска атеросклероза сонных артерий при ревматоидном артрите
IL301202A (en) 2020-09-10 2023-05-01 Vascular Biogenics Ltd Antibodies against MOTILE SPERM DOMAIN CONTAINING PROTEIN 2 and methods of using them
CN112835316B (zh) * 2021-01-06 2022-04-19 重庆医科大学 新生儿败血症休克预测系统及监控设备
CN113295874B (zh) * 2021-05-25 2022-03-04 广东源心再生医学有限公司 一种用于瓣膜性心脏病辅助诊断的新型标志物、辅助诊断的产品
CN113667739B (zh) * 2021-08-27 2023-12-26 河北医科大学第二医院 冠状动脉疾病的诊断标志物组合
CN113667740B (zh) * 2021-08-27 2023-12-26 河北医科大学第二医院 分子标志物组合在诊断心血管疾病中的应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020151479A1 (en) * 2000-01-31 2002-10-17 Rosen Craig A. Nucleic acids, proteins, and antibodies
US7235358B2 (en) * 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US20030099958A1 (en) * 2001-09-05 2003-05-29 Vitivity, Inc. Diagnosis and treatment of vascular disease
US20050032066A1 (en) * 2003-08-04 2005-02-10 Heng Chew Kiat Method for assessing risk of diseases with multiple contributing factors
US20070238124A1 (en) * 2003-10-16 2007-10-11 Chibout Salah D Differentially expressed genes related to coronary artery disease
WO2005040422A2 (en) * 2003-10-16 2005-05-06 Novartis Ag Differentially expressed genes related to coronary artery disease
WO2005103720A1 (en) * 2004-03-29 2005-11-03 Medstar Research Institute, Inc. Methods of diagnosing cardiovascular disease
EP1907858A4 (de) * 2005-06-13 2009-04-08 Univ Michigan Zusammensetzungen und verfahren zur behandlung und diagnose von krebs
US20070015170A1 (en) * 2005-07-12 2007-01-18 Oy Jurilab Ltd Method and kit for detecting a risk of coronary heart disease
EP1933880A4 (de) * 2005-09-09 2009-11-18 Quark Pharmaceuticals Inc Oligoribonukleotide und anwendungsverfahren zur behandlung von kardiovaskulären erkrankungen
WO2007146229A2 (en) * 2006-06-07 2007-12-21 Tethys Bioscience, Inc. Markers associated with arteriovascular events and methods of use thereof
WO2008080126A2 (en) * 2006-12-22 2008-07-03 Aviir, Inc. Two biomarkers for diagnosis and monitoring of atherosclerotic cardiovascular disease
HUE030996T2 (en) * 2007-02-21 2017-06-28 Decode Genetics Ehf Coronary artery disease and myocardial infarction
US7695916B2 (en) * 2007-03-22 2010-04-13 Celera Corporation Genetic polymorphisms associated with coronary events and drug response, methods of detection and uses thereof
EP2155907B1 (de) 2007-04-30 2015-05-27 Decode Genetics EHF Für die risikobeurteilung von koronarer herzkrankheit und myokardinfarkt geeignete genetische varianten
US20110184712A1 (en) * 2007-10-11 2011-07-28 Cardiodx, Inc. Predictive models and methods for diagnosing and assessing coronary artery disease
WO2010038104A1 (en) * 2008-10-03 2010-04-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Combination of cardiovascular risk factors for the diagnosis/prognosis of a cardiovascular disease/event.
DK2443449T3 (en) 2009-06-15 2017-05-15 Cardiodx Inc DETERMINATION OF RISK OF CORONARY ARTERY DISEASE

Also Published As

Publication number Publication date
EP2443449B1 (de) 2017-04-12
KR20120046171A (ko) 2012-05-09
US20150315652A1 (en) 2015-11-05
US20140156198A1 (en) 2014-06-05
EA201270020A1 (ru) 2012-07-30
EP2443449A4 (de) 2012-12-26
CA2765145A1 (en) 2010-12-23
BRPI1010693A2 (pt) 2019-07-16
SG176692A1 (en) 2012-01-30
AU2010260152A1 (en) 2012-02-02
CN102803951A (zh) 2012-11-28
US9122777B2 (en) 2015-09-01
JP2012529914A (ja) 2012-11-29
US20110015865A1 (en) 2011-01-20
DK2443449T3 (en) 2017-05-15
WO2010148017A1 (en) 2010-12-23
EP2443449A1 (de) 2012-04-25
US8914240B2 (en) 2014-12-16
IL216875A0 (en) 2012-02-29

Similar Documents

Publication Publication Date Title
IL216875A0 (en) Determination of coronary artery disease risk
EP2498796A4 (de) Behandlung von herzkrankheiten
EP2405806A4 (de) Prognose von koronararterienerkrankung und der gefahr von kardiovaskulären ereignissen
GB2473392B (en) Methods of diagnosis
EP2393914A4 (de) Lungengewebekonstruktion
IL219859A0 (en) Method and apparatus to detect coronary artery calcification or disease
PL2464408T3 (pl) Instrument cewnikowy
EP2397139A4 (de) Mittel gegen neurodegenerative erkrankungen
IL209855A0 (en) Supression of neuroedocrine diseases
GB0908193D0 (en) Treatment of disease state
GB2467840B (en) Disease determination
IL207075A0 (en) Generic markers of mental illness
GB0814533D0 (en) Measurement of bio-signals
EP2375957C0 (de) Vorspülen von geschirr
HK1138750A1 (zh) 生物信號的處理
IL210922A0 (en) Treatment of pulmonary arterial hypertension
GB0700972D0 (en) Treatment of inflammatory disease
EP2451347A4 (de) Nicht invasive messung eines physiologischen vorgangs
IL255052A0 (en) Treatment of inflammatory bowel diseases by 6-mercaptopurine
GB0720976D0 (en) Treatment of inflammatory disease
SI2491005T1 (sl) Uporaba 4-(etil(dimetil)amonio)butanoata pri zdravljenju bolezni srca in oĺ˝ilja
ZA201003867B (en) Treatment of heart disease using b-blockers
GB0903858D0 (en) Diagnosis of disease
GB0902736D0 (en) Novel biomarkers of vascular disease
GB0908666D0 (en) Treatment of proteostatic disease