SG10201400258SA - Methods Of Using SNS-595 For Treatment Of Cancer Subjects With Reduced BRCA2 Activity - Google Patents
Methods Of Using SNS-595 For Treatment Of Cancer Subjects With Reduced BRCA2 ActivityInfo
- Publication number
- SG10201400258SA SG10201400258SA SG10201400258SA SG10201400258SA SG10201400258SA SG 10201400258S A SG10201400258S A SG 10201400258SA SG 10201400258S A SG10201400258S A SG 10201400258SA SG 10201400258S A SG10201400258S A SG 10201400258SA SG 10201400258S A SG10201400258S A SG 10201400258SA
- Authority
- SG
- Singapore
- Prior art keywords
- sns
- treatment
- methods
- cancer subjects
- brca2 activity
- Prior art date
Links
- 102000052609 BRCA2 Human genes 0.000 title 1
- 108700020462 BRCA2 Proteins 0.000 title 1
- 101150008921 Brca2 gene Proteins 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- XZAFZXJXZHRNAQ-STQMWFEESA-N vosaroxin Chemical compound C1[C@H](OC)[C@@H](NC)CN1C1=CC=C2C(=O)C(C(O)=O)=CN(C=3SC=CN=3)C2=N1 XZAFZXJXZHRNAQ-STQMWFEESA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15644909P | 2009-02-27 | 2009-02-27 | |
| US17001309P | 2009-04-16 | 2009-04-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201400258SA true SG10201400258SA (en) | 2014-05-29 |
Family
ID=42224275
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2011061512A SG173855A1 (en) | 2009-02-27 | 2010-03-01 | Methods of using sns-595 for treatment of cancer subjects with reduced brca2 activity |
| SG10201400258SA SG10201400258SA (en) | 2009-02-27 | 2010-03-01 | Methods Of Using SNS-595 For Treatment Of Cancer Subjects With Reduced BRCA2 Activity |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2011061512A SG173855A1 (en) | 2009-02-27 | 2010-03-01 | Methods of using sns-595 for treatment of cancer subjects with reduced brca2 activity |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20120148564A1 (ko) |
| EP (2) | EP2400959A1 (ko) |
| JP (2) | JP5936862B2 (ko) |
| KR (2) | KR20170046193A (ko) |
| CN (2) | CN102405045A (ko) |
| AU (2) | AU2010217796B2 (ko) |
| CA (1) | CA2753261A1 (ko) |
| IL (1) | IL214784A0 (ko) |
| MX (1) | MX348412B (ko) |
| NZ (1) | NZ594829A (ko) |
| RU (1) | RU2558835C2 (ko) |
| SG (2) | SG173855A1 (ko) |
| WO (1) | WO2010099526A1 (ko) |
| ZA (1) | ZA201106199B (ko) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251589B (zh) | 2004-03-15 | 2015-09-30 | 逊尼希思制药公司 | Sns-595及其使用方法 |
| US8518872B2 (en) | 2007-10-22 | 2013-08-27 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-OXO-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid in combination therapy |
| MX2011006974A (es) | 2008-12-31 | 2011-11-18 | Sunesis Pharmaceuticals Inc | Metodo para preparar acido (+)-1,4-dihidro-7-[(3s,4s)-3-metoxi-4-( metilamino)-1-pirrolidinil]-4-oxo-1-) (2-tiazolil)-1, 8-naftiridin-3-carboxilico. |
| CN102405045A (zh) * | 2009-02-27 | 2012-04-04 | 逊尼希思制药公司 | 利用sns-595 治疗具有降低的brca2 活性的癌症对象的方法 |
| UA110465C2 (en) | 2009-09-04 | 2016-01-12 | Sunesis Pharmaceutecals Inc | Stable sns-595 composition |
| US8470817B2 (en) | 2009-10-26 | 2013-06-25 | Sunesis Pharmaceuticals, Inc. | Compounds and methods for treatment of cancer |
| EP4448565A1 (en) | 2021-12-15 | 2024-10-23 | Y-Mabs Therapeutics, Inc. | Scfv and antibodies with reduced multimerisation |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6024A (en) * | 1849-01-09 | Cast-iron gar-wheel | ||
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| CZ292631B6 (cs) | 1994-06-14 | 2003-11-12 | Dainippon Pharmaceutical Co., Ltd. | Deriváty pyridonkarboxylové kyseliny, protinádorové a farmakologické prostředky je obsahující |
| JPH10173986A (ja) | 1996-12-16 | 1998-06-26 | Sony Corp | 移動体撮影装置 |
| TWI338000B (en) * | 2003-12-01 | 2011-03-01 | Kudos Pharm Ltd | Dna damage repair inhibitors for treatment of cancer |
| CN103251589B (zh) | 2004-03-15 | 2015-09-30 | 逊尼希思制药公司 | Sns-595及其使用方法 |
| EP1931339B1 (en) * | 2005-09-02 | 2018-05-16 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer |
| CA2654876A1 (en) | 2006-06-12 | 2007-12-21 | Sunesis Pharmaceuticals, Inc. | 1-8-naphthyridine compounds for the treatment of cancer |
| US7790274B2 (en) | 2006-08-02 | 2010-09-07 | High Impact Technology, Llc | Layered panel structure including self-bonded thermoformable and non-thermoformable layer materials |
| CA2680692A1 (en) * | 2007-03-30 | 2008-10-09 | Source Precision Medicine, Inc. D/B/A Source Mdx | Gene expression profiling for identification, monitoring, and treatment of prostate cancer |
| CN102405045A (zh) * | 2009-02-27 | 2012-04-04 | 逊尼希思制药公司 | 利用sns-595 治疗具有降低的brca2 活性的癌症对象的方法 |
-
2010
- 2010-03-01 CN CN2010800172031A patent/CN102405045A/zh active Pending
- 2010-03-01 CA CA2753261A patent/CA2753261A1/en not_active Abandoned
- 2010-03-01 US US13/203,718 patent/US20120148564A1/en not_active Abandoned
- 2010-03-01 WO PCT/US2010/025737 patent/WO2010099526A1/en active Application Filing
- 2010-03-01 EP EP10707173A patent/EP2400959A1/en not_active Withdrawn
- 2010-03-01 CN CN201410799921.9A patent/CN104688732A/zh active Pending
- 2010-03-01 AU AU2010217796A patent/AU2010217796B2/en not_active Ceased
- 2010-03-01 KR KR1020177010758A patent/KR20170046193A/ko not_active Application Discontinuation
- 2010-03-01 JP JP2011552217A patent/JP5936862B2/ja not_active Expired - Fee Related
- 2010-03-01 KR KR1020117022340A patent/KR20110132400A/ko active Application Filing
- 2010-03-01 MX MX2011008994A patent/MX348412B/es active IP Right Grant
- 2010-03-01 SG SG2011061512A patent/SG173855A1/en unknown
- 2010-03-01 NZ NZ594829A patent/NZ594829A/xx not_active IP Right Cessation
- 2010-03-01 RU RU2011139323/15A patent/RU2558835C2/ru not_active IP Right Cessation
- 2010-03-01 SG SG10201400258SA patent/SG10201400258SA/en unknown
- 2010-03-01 EP EP17179348.2A patent/EP3287126A1/en not_active Withdrawn
-
2011
- 2011-08-22 IL IL214784A patent/IL214784A0/en unknown
- 2011-08-23 ZA ZA2011/06199A patent/ZA201106199B/en unknown
-
2014
- 2014-09-03 US US14/476,606 patent/US20150202189A1/en not_active Abandoned
-
2015
- 2015-03-24 JP JP2015060900A patent/JP2015145396A/ja active Pending
- 2015-07-30 AU AU2015207901A patent/AU2015207901A1/en not_active Abandoned
-
2016
- 2016-08-10 US US15/233,860 patent/US20170182015A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010217796B2 (en) | 2015-04-30 |
| US20170182015A1 (en) | 2017-06-29 |
| RU2011139323A (ru) | 2013-04-10 |
| ZA201106199B (en) | 2012-10-31 |
| CN104688732A (zh) | 2015-06-10 |
| MX348412B (es) | 2017-06-12 |
| EP3287126A1 (en) | 2018-02-28 |
| WO2010099526A1 (en) | 2010-09-02 |
| EP2400959A1 (en) | 2012-01-04 |
| RU2558835C2 (ru) | 2015-08-10 |
| AU2010217796A1 (en) | 2011-09-15 |
| KR20110132400A (ko) | 2011-12-07 |
| JP2012523376A (ja) | 2012-10-04 |
| US20120148564A1 (en) | 2012-06-14 |
| US20150202189A1 (en) | 2015-07-23 |
| MX2011008994A (es) | 2011-09-15 |
| CA2753261A1 (en) | 2010-09-02 |
| AU2015207901A1 (en) | 2015-08-20 |
| JP2015145396A (ja) | 2015-08-13 |
| KR20170046193A (ko) | 2017-04-28 |
| NZ594829A (en) | 2013-09-27 |
| IL214784A0 (en) | 2011-11-30 |
| SG173855A1 (en) | 2011-09-29 |
| CN102405045A (zh) | 2012-04-04 |
| JP5936862B2 (ja) | 2016-06-22 |
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