SE9403613D0 - Improvement of an expression vector for production of recombinant proteins - Google Patents

Improvement of an expression vector for production of recombinant proteins

Info

Publication number
SE9403613D0
SE9403613D0 SE9403613A SE9403613A SE9403613D0 SE 9403613 D0 SE9403613 D0 SE 9403613D0 SE 9403613 A SE9403613 A SE 9403613A SE 9403613 A SE9403613 A SE 9403613A SE 9403613 D0 SE9403613 D0 SE 9403613D0
Authority
SE
Sweden
Prior art keywords
dna construct
improvement
production
gene
expression vector
Prior art date
Application number
SE9403613A
Other languages
English (en)
Inventor
Gunnar Norstedt
Tim Wood
Daniel Sliva
Bertil Enberg
Peter Lobie
Lars-Arne Haldosen
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Priority to SE9403613A priority Critical patent/SE9403613D0/sv
Publication of SE9403613D0 publication Critical patent/SE9403613D0/sv
Priority to EP95936162A priority patent/EP0782628B1/en
Priority to EP03000821A priority patent/EP1338653A3/en
Priority to CA002200465A priority patent/CA2200465A1/en
Priority to AU38202/95A priority patent/AU705594B2/en
Priority to DE69533840T priority patent/DE69533840T2/de
Priority to DK95936162T priority patent/DK0782628T3/da
Priority to PCT/SE1995/001235 priority patent/WO1996012815A1/en
Priority to AT95936162T priority patent/ATE284447T1/de
Priority to JP8513832A priority patent/JPH10507633A/ja
Priority to PT95936162T priority patent/PT782628E/pt
Priority to ES95936162T priority patent/ES2235175T3/es
Priority to NZ294968A priority patent/NZ294968A/en
Priority to MXPA/A/1997/002889A priority patent/MXPA97002889A/xx
Priority to US08/963,288 priority patent/US6773919B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/30—Vector systems having a special element relevant for transcription being an enhancer not forming part of the promoter region
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SE9403613A 1994-10-21 1994-10-21 Improvement of an expression vector for production of recombinant proteins SE9403613D0 (sv)

Priority Applications (15)

Application Number Priority Date Filing Date Title
SE9403613A SE9403613D0 (sv) 1994-10-21 1994-10-21 Improvement of an expression vector for production of recombinant proteins
NZ294968A NZ294968A (en) 1994-10-21 1995-10-19 Expression vector for production of recombinant proteins
DK95936162T DK0782628T3 (da) 1994-10-21 1995-10-19 Forbedring af en ekspressionsvektor til fremstilling af rekombinante proteiner
AT95936162T ATE284447T1 (de) 1994-10-21 1995-10-19 Verbesserter expressionsvektor für die herstellung rekombinanter proteine
CA002200465A CA2200465A1 (en) 1994-10-21 1995-10-19 Improvement of an expression vector for production of recombinant proteins
AU38202/95A AU705594B2 (en) 1994-10-21 1995-10-19 Improvement of an expression vector for production of recombinant proteins
DE69533840T DE69533840T2 (de) 1994-10-21 1995-10-19 Verbesserter expressionsvektor für die herstellung rekombinanter proteine
EP95936162A EP0782628B1 (en) 1994-10-21 1995-10-19 Improvement of an expression vector for production of recombinant proteins
PCT/SE1995/001235 WO1996012815A1 (en) 1994-10-21 1995-10-19 Improvement of an expression vector for production of recombinant proteins
EP03000821A EP1338653A3 (en) 1994-10-21 1995-10-19 Improvement of an expression vector for production of recombinant proteins
JP8513832A JPH10507633A (ja) 1994-10-21 1995-10-19 組換え蛋白質生産用発現ベクターの改良
PT95936162T PT782628E (pt) 1994-10-21 1995-10-19 Melhoramento de um vector de expressao para a producao de proteinas recombinantes
ES95936162T ES2235175T3 (es) 1994-10-21 1995-10-19 Mejora de un vestor de expresion para la produccion de proteinas recombinantes.
MXPA/A/1997/002889A MXPA97002889A (en) 1994-10-21 1997-04-21 Improvement of a vector of expression for the production of proteins recombin
US08/963,288 US6773919B2 (en) 1994-10-21 1997-11-03 Expression vector for production of recombinant proteins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9403613A SE9403613D0 (sv) 1994-10-21 1994-10-21 Improvement of an expression vector for production of recombinant proteins

Publications (1)

Publication Number Publication Date
SE9403613D0 true SE9403613D0 (sv) 1994-10-21

Family

ID=20395702

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9403613A SE9403613D0 (sv) 1994-10-21 1994-10-21 Improvement of an expression vector for production of recombinant proteins

Country Status (12)

Country Link
US (1) US6773919B2 (sv)
EP (2) EP0782628B1 (sv)
JP (1) JPH10507633A (sv)
AT (1) ATE284447T1 (sv)
AU (1) AU705594B2 (sv)
CA (1) CA2200465A1 (sv)
DE (1) DE69533840T2 (sv)
ES (1) ES2235175T3 (sv)
NZ (1) NZ294968A (sv)
PT (1) PT782628E (sv)
SE (1) SE9403613D0 (sv)
WO (1) WO1996012815A1 (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19701141C1 (de) 1997-01-16 1998-04-09 Hoechst Ag Genkonstrukte für durch Proteasen aktivierbare Wirksubstanzen
AR056792A1 (es) * 2005-11-12 2007-10-24 Unilever Nv Dispensador capilar

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7879987A (en) * 1986-08-28 1988-03-24 Immunex Corp. Expression of heterologous proteins by transgenic lactating mammals
US5082779A (en) * 1987-08-06 1992-01-21 Edison Animal Biotechnology Center/Ohio University Method of directing transgenic expression in animals using a prolactin promoter
AU649407B2 (en) * 1989-09-21 1994-05-26 Infigen, Inc. Enhanced gene expression in response to lactation signals
US5831141A (en) * 1991-01-11 1998-11-03 United States Of America As Represented By The Department Of Health And Human Services Expression of a heterologous polypeptide in mammary tissue of transgenic non-human mammals using a long whey acidic protein promoter
US5814517A (en) * 1994-04-14 1998-09-29 Ligand Pharmaceuticals, Inc. DNA spacer regulatory elements responsive to cytokines and methods for their use

Also Published As

Publication number Publication date
JPH10507633A (ja) 1998-07-28
MX9702889A (es) 1997-07-31
US20030192064A1 (en) 2003-10-09
DE69533840D1 (de) 2005-01-13
EP1338653A3 (en) 2004-04-21
AU3820295A (en) 1996-05-15
EP0782628B1 (en) 2004-12-08
NZ294968A (en) 1998-08-26
ES2235175T3 (es) 2005-07-01
PT782628E (pt) 2005-04-29
EP0782628A1 (en) 1997-07-09
US6773919B2 (en) 2004-08-10
EP1338653A2 (en) 2003-08-27
AU705594B2 (en) 1999-05-27
CA2200465A1 (en) 1996-05-02
WO1996012815A1 (en) 1996-05-02
ATE284447T1 (de) 2004-12-15
DE69533840T2 (de) 2005-12-08

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