SE9402642D0 - Gene Therapy - Google Patents

Gene Therapy

Info

Publication number
SE9402642D0
SE9402642D0 SE9402642A SE9402642A SE9402642D0 SE 9402642 D0 SE9402642 D0 SE 9402642D0 SE 9402642 A SE9402642 A SE 9402642A SE 9402642 A SE9402642 A SE 9402642A SE 9402642 D0 SE9402642 D0 SE 9402642D0
Authority
SE
Sweden
Prior art keywords
dna
mutation
individual
disease
fragment
Prior art date
Application number
SE9402642A
Other languages
Swedish (sv)
Inventor
Maria Anvret
Margareta Blombaeck
Zhiping Zhang
Original Assignee
Maria Anvret
Margareta Blombaeck
Zhiping Zhang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maria Anvret, Margareta Blombaeck, Zhiping Zhang filed Critical Maria Anvret
Priority to SE9402642A priority Critical patent/SE9402642D0/en
Publication of SE9402642D0 publication Critical patent/SE9402642D0/en
Priority to AU12854/95A priority patent/AU1285495A/en
Priority to PCT/SE1994/001038 priority patent/WO1996004397A1/en

Links

Abstract

The present invention is related to a method to correct the mutation(s) behind a genetic disease in the genome of somatic cells derived from an individual afflicted with this disease by contacting said cells with the corresponding non-mutant DNA-fragment to allow it to undergo homologous recombination with and, thus, replace a DNA sequence of the somatic cell genome, wherein said mutation(s) is(are) located. The cells obtained according to the invention can be administered to an individual as a treatment of the said disease. The present invention is also related to a DNA-liposome suspension comprising the said non-mutant DNA-fragment. The said suspension can be used as a DNA-vehicle in the above process. In addition, it can be administered to an individual to obtain correction of mutation(s) by in vivo integration of the said DNA into a mutated gene by homologous recombination.
SE9402642A 1994-08-05 1994-08-05 Gene Therapy SE9402642D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE9402642A SE9402642D0 (en) 1994-08-05 1994-08-05 Gene Therapy
AU12854/95A AU1285495A (en) 1994-08-05 1994-11-03 Gene therapy using homologous recombination
PCT/SE1994/001038 WO1996004397A1 (en) 1994-08-05 1994-11-03 Gene therapy using homologous recombination

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9402642A SE9402642D0 (en) 1994-08-05 1994-08-05 Gene Therapy

Publications (1)

Publication Number Publication Date
SE9402642D0 true SE9402642D0 (en) 1994-08-05

Family

ID=20394857

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9402642A SE9402642D0 (en) 1994-08-05 1994-08-05 Gene Therapy

Country Status (3)

Country Link
AU (1) AU1285495A (en)
SE (1) SE9402642D0 (en)
WO (1) WO1996004397A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792632A (en) 1992-05-05 1998-08-11 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
US6395959B1 (en) 1992-05-05 2002-05-28 Institut Pasteur Nucleotide sequence encoding the enzyme I SceI and the use thereof
RU2313349C2 (en) * 2006-01-16 2007-12-27 Михаил Аркадьевич Шурдов Method for treating oncological diseases
RU2322264C1 (en) * 2006-07-27 2008-04-20 Михаил Аркадьевич Шурдов Method for treating diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05507853A (en) * 1990-06-12 1993-11-11 ベイラー・カレッジ・オブ・メディシン Homologous recombination methods in animal and plant cells
NZ245015A (en) * 1991-11-05 1995-12-21 Transkaryotic Therapies Inc Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production
WO1993022443A1 (en) * 1992-04-24 1993-11-11 Sri International In vivo homologous sequence targeting in eukaryotic cells
WO1994004032A1 (en) * 1992-08-21 1994-03-03 The Regents Of The University Of California Composition and method for altering dna sequences by homologous recombination

Also Published As

Publication number Publication date
WO1996004397A1 (en) 1996-02-15
AU1285495A (en) 1996-03-04

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