SE9402642D0 - Gene Therapy - Google Patents
Gene TherapyInfo
- Publication number
- SE9402642D0 SE9402642D0 SE9402642A SE9402642A SE9402642D0 SE 9402642 D0 SE9402642 D0 SE 9402642D0 SE 9402642 A SE9402642 A SE 9402642A SE 9402642 A SE9402642 A SE 9402642A SE 9402642 D0 SE9402642 D0 SE 9402642D0
- Authority
- SE
- Sweden
- Prior art keywords
- dna
- mutation
- individual
- disease
- fragment
- Prior art date
Links
Abstract
The present invention is related to a method to correct the mutation(s) behind a genetic disease in the genome of somatic cells derived from an individual afflicted with this disease by contacting said cells with the corresponding non-mutant DNA-fragment to allow it to undergo homologous recombination with and, thus, replace a DNA sequence of the somatic cell genome, wherein said mutation(s) is(are) located. The cells obtained according to the invention can be administered to an individual as a treatment of the said disease. The present invention is also related to a DNA-liposome suspension comprising the said non-mutant DNA-fragment. The said suspension can be used as a DNA-vehicle in the above process. In addition, it can be administered to an individual to obtain correction of mutation(s) by in vivo integration of the said DNA into a mutated gene by homologous recombination.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9402642A SE9402642D0 (en) | 1994-08-05 | 1994-08-05 | Gene Therapy |
AU12854/95A AU1285495A (en) | 1994-08-05 | 1994-11-03 | Gene therapy using homologous recombination |
PCT/SE1994/001038 WO1996004397A1 (en) | 1994-08-05 | 1994-11-03 | Gene therapy using homologous recombination |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9402642A SE9402642D0 (en) | 1994-08-05 | 1994-08-05 | Gene Therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9402642D0 true SE9402642D0 (en) | 1994-08-05 |
Family
ID=20394857
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9402642A SE9402642D0 (en) | 1994-08-05 | 1994-08-05 | Gene Therapy |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU1285495A (en) |
SE (1) | SE9402642D0 (en) |
WO (1) | WO1996004397A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5792632A (en) | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
US6395959B1 (en) | 1992-05-05 | 2002-05-28 | Institut Pasteur | Nucleotide sequence encoding the enzyme I SceI and the use thereof |
RU2313349C2 (en) * | 2006-01-16 | 2007-12-27 | Михаил Аркадьевич Шурдов | Method for treating oncological diseases |
RU2322264C1 (en) * | 2006-07-27 | 2008-04-20 | Михаил Аркадьевич Шурдов | Method for treating diseases |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05507853A (en) * | 1990-06-12 | 1993-11-11 | ベイラー・カレッジ・オブ・メディシン | Homologous recombination methods in animal and plant cells |
NZ245015A (en) * | 1991-11-05 | 1995-12-21 | Transkaryotic Therapies Inc | Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production |
WO1993022443A1 (en) * | 1992-04-24 | 1993-11-11 | Sri International | In vivo homologous sequence targeting in eukaryotic cells |
WO1994004032A1 (en) * | 1992-08-21 | 1994-03-03 | The Regents Of The University Of California | Composition and method for altering dna sequences by homologous recombination |
-
1994
- 1994-08-05 SE SE9402642A patent/SE9402642D0/en unknown
- 1994-11-03 WO PCT/SE1994/001038 patent/WO1996004397A1/en active Application Filing
- 1994-11-03 AU AU12854/95A patent/AU1285495A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1996004397A1 (en) | 1996-02-15 |
AU1285495A (en) | 1996-03-04 |
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