SE9302006D0 - PROTEIN FORMULATION - Google Patents

PROTEIN FORMULATION

Info

Publication number
SE9302006D0
SE9302006D0 SE9302006A SE9302006A SE9302006D0 SE 9302006 D0 SE9302006 D0 SE 9302006D0 SE 9302006 A SE9302006 A SE 9302006A SE 9302006 A SE9302006 A SE 9302006A SE 9302006 D0 SE9302006 D0 SE 9302006D0
Authority
SE
Sweden
Prior art keywords
composition
polysorbate
stabilizing agent
factor viii
coagulation factor
Prior art date
Application number
SE9302006A
Other languages
Swedish (sv)
Inventor
*Oesterberg Thomas
*Fatouros Angelica
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9202878A external-priority patent/SE9202878D0/en
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Priority to SE9302006A priority Critical patent/SE9302006D0/en
Publication of SE9302006D0 publication Critical patent/SE9302006D0/en
Priority to AT99121997T priority patent/ATE316981T1/en
Priority to RU94032143A priority patent/RU2136294C1/en
Priority to EP06001883A priority patent/EP1652534A3/en
Priority to DE69329795T priority patent/DE69329795T2/en
Priority to EP99121997A priority patent/EP1016673B1/en
Priority to SK659-94A priority patent/SK282483B6/en
Priority to CA002124690A priority patent/CA2124690C/en
Priority to DK93923080T priority patent/DK0627924T3/en
Priority to EP93923080A priority patent/EP0627924B1/en
Priority to PCT/SE1993/000793 priority patent/WO1994007510A1/en
Priority to NZ256921A priority patent/NZ256921A/en
Priority to ES93923080T priority patent/ES2154650T3/en
Priority to JP50895794A priority patent/JP3905921B2/en
Priority to US08/244,266 priority patent/US5733873A/en
Priority to AU52883/93A priority patent/AU677797C/en
Priority to HU9401382A priority patent/HU220194B/en
Priority to PT93923080T priority patent/PT627924E/en
Priority to DE69333974T priority patent/DE69333974T2/en
Priority to AT93923080T priority patent/ATE198277T1/en
Priority to MX9306133A priority patent/MX9306133A/en
Priority to CZ19941328A priority patent/CZ290342B6/en
Priority to KR1019940701858A priority patent/KR100303872B1/en
Priority to NO942033A priority patent/NO942033D0/en
Priority to FI942573A priority patent/FI111443B/en
Priority to HU95P/P00473P priority patent/HU211670A9/en
Priority to US08/863,198 priority patent/US5919766A/en
Priority to GR20010400311T priority patent/GR3035472T3/en

Links

Abstract

FIELD: medicine. SUBSTANCE: invention relates to the new composition that involves coagulation factor VIII and nonionogenic surface-active substance, for example, block-copolymer, polyoxamer or ester of polyhydroxyethylene (20) derivative of sorbitol with fatty acid, for example, polysorbate-20 or polysorbate-80 as stabilizing agent. Composition can involve also sodium chloride, calcium chloride, L-histidine and/or sugars of sugar alcohols. Invention relates to the use of noninogenic surface-active substance as stabilizing agent in composition containing coagulation factor VIII also. EFFECT: new composition indicated above.
SE9302006A 1992-10-02 1993-06-11 PROTEIN FORMULATION SE9302006D0 (en)

Priority Applications (28)

Application Number Priority Date Filing Date Title
SE9302006A SE9302006D0 (en) 1992-10-02 1993-06-11 PROTEIN FORMULATION
CZ19941328A CZ290342B6 (en) 1992-10-02 1993-10-01 Storage-stable composition containing coagulation factor VIII and non-ionic surface-active substance and process for preparing thereof
KR1019940701858A KR100303872B1 (en) 1992-10-02 1993-10-01 Compositions containing coagulation factor formulations, methods for their preparation and use of surfactants as stabilizers
NZ256921A NZ256921A (en) 1992-10-02 1993-10-01 Formulations of coagulation factor viii and a non-ionic surfactant and their preparation
US08/244,266 US5733873A (en) 1992-10-02 1993-10-01 Composition comprising coagulation factor VIII formulation, process for its preparation and use of a surfactant as stabilizer
EP06001883A EP1652534A3 (en) 1992-10-02 1993-10-01 Composition comprising coagulation factor VIII formulation, process for its preparation and use of a surfactant as stabilizer
DE69329795T DE69329795T2 (en) 1992-10-02 1993-10-01 COMPOSITION CONTAINING COAGULATION FACTOR VIII; METHOD FOR THE PRODUCTION THEREOF AND THE USE OF A SURFACE-ACTIVE SUBSTANCE AS A STABILIZER
EP99121997A EP1016673B1 (en) 1992-10-02 1993-10-01 Composition comprising coagulation factor VIII formulation, process for its preparation and use of a surfactant as stabilizer
SK659-94A SK282483B6 (en) 1992-10-02 1993-10-01 Stable composition of coagulating factor viii, its preparation and stabilisation method
CA002124690A CA2124690C (en) 1992-10-02 1993-10-01 Composition comprising coagulation factor viii formulation, process for its preparation and use of a surfactant as stabilizer
DK93923080T DK0627924T3 (en) 1992-10-02 1993-10-01 Composition comprising coagulation factor VIII formulation, process for its preparation and use of a surfactant as stabilizer
EP93923080A EP0627924B1 (en) 1992-10-02 1993-10-01 Composition comprising coagulation factor viii formulation, process for its preparation and use of a surfactant as stabilizer
PCT/SE1993/000793 WO1994007510A1 (en) 1992-10-02 1993-10-01 Composition comprising coagulation factor viii formulation, process for its preparation and use of a surfactant as stabilizer
AT99121997T ATE316981T1 (en) 1992-10-02 1993-10-01 COMPOSITION INCLUDING COAGULATION FACTOR VIII; METHOD FOR THE PRODUCTION THEREOF AND THE USE OF A SURFACE-ACTIVE SUBSTANCE AS A STABILIZER
ES93923080T ES2154650T3 (en) 1992-10-02 1993-10-01 COMPOSITION THAT INCLUDES A FORMULATION WITH COAGULATION FACTOR VIII, PROCEDURE FOR THE PREPARATION AND USE OF A TENSIOACTIVE AS A STABILIZER.
JP50895794A JP3905921B2 (en) 1992-10-02 1993-10-01 COMPOSITION CONTAINING COAGULATION FACTOR VIII, METHOD FOR PRODUCING THE SAME, AND METHOD FOR USING SURFACTANT AS STABILIATOR
RU94032143A RU2136294C1 (en) 1992-10-02 1993-10-01 Composition containing preparation of clotting factor viii, method of its preparing and use of surface-active substance as stabilizing agent
AU52883/93A AU677797C (en) 1992-10-02 1993-10-01 Composition comprising coagulation factor viii formulation, process for its preparation and use of a surfactant as stabilizer
HU9401382A HU220194B (en) 1992-10-02 1993-10-01 Composition comprising coagulation factor viii formulation and process for its preparation
PT93923080T PT627924E (en) 1992-10-02 1993-10-01 COMPOSITION FOR COMPOSITION OF THE COAGULATION FACTOR VIII PROCESS FOR PREPARING AND USING A STATICIZING STRENGTH AS A STABILIZER
DE69333974T DE69333974T2 (en) 1992-10-02 1993-10-01 Composition containing coagulation factor VIII; Process for their preparation and the use of a surfactant as stabilizer
AT93923080T ATE198277T1 (en) 1992-10-02 1993-10-01 COMPOSITION INCLUDING COAGULATION FACTOR VIII; METHOD FOR THE PRODUCTION THEREOF AND THE USE OF A SURFACE-ACTIVE SUBSTANCE AS A STABILIZER
MX9306133A MX9306133A (en) 1992-10-02 1993-10-01 COMPOSITION THAT INCLUDES A FORMULATION OF THE COAGULATION FACTOR VIII, PROCESS FOR ITS PREPARATION AND USE OF A SURFACTANT AS A STABILIZER.
FI942573A FI111443B (en) 1992-10-02 1994-06-01 A process for preparing a composition for stabilizing recombinant coagulation factor VIII
NO942033A NO942033D0 (en) 1992-10-02 1994-06-01 Preparation comprising coagulation factor VIII, method of preparation thereof and use of a surfactant as stabilizer
HU95P/P00473P HU211670A9 (en) 1992-10-02 1995-06-28 Composition comprising coagulation factor viii formulation, process for its preparation and use of a surfactant as stabilizer
US08/863,198 US5919766A (en) 1992-10-02 1997-05-27 Composition comprising coagulation factor VIII formulation, process for its preparation and use of a surfactant as stabilizer
GR20010400311T GR3035472T3 (en) 1992-10-02 2001-02-23 Composition comprising coagulation factor viii formulation, process for its preparation and use of a surfactant as stabilizer.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9202878A SE9202878D0 (en) 1992-10-02 1992-10-02 PROTEIN FORMULATION
SE9302006A SE9302006D0 (en) 1992-10-02 1993-06-11 PROTEIN FORMULATION

Publications (1)

Publication Number Publication Date
SE9302006D0 true SE9302006D0 (en) 1993-06-11

Family

ID=26661537

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9302006A SE9302006D0 (en) 1992-10-02 1993-06-11 PROTEIN FORMULATION

Country Status (2)

Country Link
RU (1) RU2136294C1 (en)
SE (1) SE9302006D0 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5323072B2 (en) * 2007-07-11 2013-10-23 ノボ・ノルデイスク・エー/エス Purification of Factor VIII using mixed or multimodal resins

Also Published As

Publication number Publication date
RU2136294C1 (en) 1999-09-10
RU94032143A (en) 1996-08-20

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