SE8903364L - New substd. phenoxy acids - useful as therapeutically active substances to inhibit thromboxane prodn. and human thrombocyte aggregation - Google Patents

New substd. phenoxy acids - useful as therapeutically active substances to inhibit thromboxane prodn. and human thrombocyte aggregation

Info

Publication number
SE8903364L
SE8903364L SE8903364A SE8903364A SE8903364L SE 8903364 L SE8903364 L SE 8903364L SE 8903364 A SE8903364 A SE 8903364A SE 8903364 A SE8903364 A SE 8903364A SE 8903364 L SE8903364 L SE 8903364L
Authority
SE
Sweden
Prior art keywords
acid
prodn
useful
active substances
therapeutically active
Prior art date
Application number
SE8903364A
Other languages
Swedish (sv)
Other versions
SE8903364D0 (en
Inventor
P H Ylitalo
Original Assignee
Huhtamaeki Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huhtamaeki Oy filed Critical Huhtamaeki Oy
Priority to SE8903364A priority Critical patent/SE8903364L/en
Publication of SE8903364D0 publication Critical patent/SE8903364D0/en
Priority to SE9001823A priority patent/SE9001823L/en
Publication of SE8903364L publication Critical patent/SE8903364L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The ring-substituted phenoxy acids have the general formula (I). In which -A- is a straight-chained or branched alkylene group with 1 to 4 carbon atoms, and R', R'' and R''' independently are chlorine or alkyl with 1-4 carbon atoms, such as their pharmaceutically usable salts. The alkyl groups are pref. methyl or ethyl. Usable cpds. are:- 2,4-dichlorophenoxy acetic acid, 2-(2,4-dichlorophenoxy) propionic acid, 4-(2,4 dichlorophenoxy) butyric acid, 2,4,5-tricholorphenoxy acetic acid, 2-(2,4,5-trichlorophenoxy) butyric acid, 2,4,5 trichlorophenoxy acetic acid, 2-(2,4,5-trichlorphenoxy) propionic acid, 4-chloro-2-methylphenoxy) propionic acid, 2-(4-chloro-2-methylphenoxy) propionic acid, 4-(4-chloro-2-methylphenoxy) butyric acid.
SE8903364A 1989-10-13 1989-10-13 New substd. phenoxy acids - useful as therapeutically active substances to inhibit thromboxane prodn. and human thrombocyte aggregation SE8903364L (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SE8903364A SE8903364L (en) 1989-10-13 1989-10-13 New substd. phenoxy acids - useful as therapeutically active substances to inhibit thromboxane prodn. and human thrombocyte aggregation
SE9001823A SE9001823L (en) 1989-10-13 1990-05-21 PHENOXIC ACIDS USE AS THERAPEUTICALLY ACTIVE SUBSTANCES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8903364A SE8903364L (en) 1989-10-13 1989-10-13 New substd. phenoxy acids - useful as therapeutically active substances to inhibit thromboxane prodn. and human thrombocyte aggregation

Publications (2)

Publication Number Publication Date
SE8903364D0 SE8903364D0 (en) 1989-10-13
SE8903364L true SE8903364L (en) 1991-04-14

Family

ID=20377124

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8903364A SE8903364L (en) 1989-10-13 1989-10-13 New substd. phenoxy acids - useful as therapeutically active substances to inhibit thromboxane prodn. and human thrombocyte aggregation
SE9001823A SE9001823L (en) 1989-10-13 1990-05-21 PHENOXIC ACIDS USE AS THERAPEUTICALLY ACTIVE SUBSTANCES

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE9001823A SE9001823L (en) 1989-10-13 1990-05-21 PHENOXIC ACIDS USE AS THERAPEUTICALLY ACTIVE SUBSTANCES

Country Status (1)

Country Link
SE (2) SE8903364L (en)

Also Published As

Publication number Publication date
SE9001823D0 (en) 1990-05-21
SE9001823L (en) 1991-04-14
SE8903364D0 (en) 1989-10-13

Similar Documents

Publication Publication Date Title
ES2058024A1 (en) A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent.
NO176082C (en) Process for the Preparation of a Pharmaceutical Preparation Containing Bunazosin, for Percutaneous Delivery
DE3775754D1 (en) ALPHA-HALOGENED DICARBONIC ACIDS CONTAINING PHARMACEUTICAL COMPOSITIONS.
SE8903364L (en) New substd. phenoxy acids - useful as therapeutically active substances to inhibit thromboxane prodn. and human thrombocyte aggregation
JPS5791913A (en) Pharmaceutical preparation of drug
WO2003055559A8 (en) Dialkyl-substituted acetic acid and glyceric acid based active substance combinations against bacteria, mycota and viruses
AU562423B2 (en) Benzoic acid derivatives
MY100483A (en) Niflumic acid morpholinoethyl ester diniflumate, preparation, use in therapeutics as analgesic and anti- inflammatory
DE69108580D1 (en) Optically active derivative of d-2- (6-methoxy-2-naphthyl) propionic acid and pharmaceutical compositions containing it.
AU528704B2 (en) 4-(2:-pyridyl-amino) phenyl acetic acid derivatives and their use as anti-inflammatory agents and analgesics
AU1027592A (en) New salts of 2-(2,6-dichloroanilino)-phenylacetic acid, a process for their preparation and their use for pharmaceutical preparations to be applied locally
AU3983595A (en) Novel (+)-(s)-2-(3-benzoylphenyl)propionic acid derivatives with analgesic action and the process for the preparation thereof
WO1996004987A1 (en) Self-emulsifying and/or emollient agents
ES8506614A1 (en) Derivatives of d-2-(6-methoxy-2-naphthyl)-propionic acid having therapeutical activity, process for their preparation and pharmaceutical compositions containing them.
GR3018126T3 (en) 4-[(Thiophene-2-carbonyl)oxy]pyrrolidine-2-carboxylic acid, its preparation and its use as anti-inflammatory and anti-dystrophic agent.
IT1255236B (en) Hydrophilic pharmaceutical composition for topical use
AU4356489A (en) Branched-chain alkyl esters of 2-(4-(2-piperidino-ethoxy)- benzoyl)-benzoic acid, processes for their preparation and their use as spasmolytic agents
EP0393782A3 (en) Catecholamine esters
IT1165076B (en) 5-Pyridoxinyl ester derivs. of pharmaceutically active acids - useful as antiinflammatories, analgesics and antipyretics
MX9704260A (en) Process for the preparation of 2,3-pyridinedicarboximides.
IT1249648B (en) Anti-inflammatory and anti-atherosclerotic salicylate derivative with prolonged action
ES2007236A6 (en) N-hydroxy:ethyl isobutyl-phenyl propionamide prepn.
JPS5295630A (en) Propionic acid and pyruvic acid derivatives
CA2120045A1 (en) Use of Hyaluronic Acid and Forms to Prevent Arterial Restenosis

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 8903364-1

Effective date: 19930501