SE8903047D0 - UNDECYLESTES OF N-CHLOROPHENOXYOSOIC ACID AND ON THIS ESTER BASED PHARMACEUTICAL PREPARATION FOR TREATMENT OF HYPERLIPIDEMIA - Google Patents

UNDECYLESTES OF N-CHLOROPHENOXYOSOIC ACID AND ON THIS ESTER BASED PHARMACEUTICAL PREPARATION FOR TREATMENT OF HYPERLIPIDEMIA

Info

Publication number
SE8903047D0
SE8903047D0 SE8903047A SE8903047A SE8903047D0 SE 8903047 D0 SE8903047 D0 SE 8903047D0 SE 8903047 A SE8903047 A SE 8903047A SE 8903047 A SE8903047 A SE 8903047A SE 8903047 D0 SE8903047 D0 SE 8903047D0
Authority
SE
Sweden
Prior art keywords
pharmaceutical preparation
acid
undecylestes
chlorophenoxyosoic
hyperlipidemia
Prior art date
Application number
SE8903047A
Other languages
Swedish (sv)
Other versions
SE8903047L (en
Inventor
L N Volovelsky
Original Assignee
Kh Nauchno Issledovatelskyinst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kh Nauchno Issledovatelskyinst filed Critical Kh Nauchno Issledovatelskyinst
Publication of SE8903047D0 publication Critical patent/SE8903047D0/en
Publication of SE8903047L publication Critical patent/SE8903047L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers
    • C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C07C69/736—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a new substance-undecylic ether n-chlorophenoxyisobutyric acid and to a pharmaceutical preparation based on it. The undecylic ether n-chlorophenoxyisobutyric acid has formula (I). The claimed combination is an active component of a pharmaceutical preparation for treating hyperlipemia. The claimed preparation is used medically for treating hyperlipemia, in particular arteriosclerosis and a number of vascular diseases.
SE8903047A 1988-01-22 1989-09-15 UNDECYLESTES OF N-CHLOROPHENOXYOSOIC ACID AND ON THIS ESTER BASED PHARMACEUTICAL PREPARATION FOR TREATMENT OF HYPERLIPIDEMIA SE8903047L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SU1988/000019 WO1989006643A1 (en) 1988-01-22 1988-01-22 UNDECYLIC ETHER n-CHLOROPHENOXYISOBUTYRIC ACID AND A PHARMACEUTICAL PREPARATION FOR TREATING HYPERLIPEMIA BASED ON IT

Publications (2)

Publication Number Publication Date
SE8903047D0 true SE8903047D0 (en) 1989-09-15
SE8903047L SE8903047L (en) 1989-09-15

Family

ID=21617183

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8903047A SE8903047L (en) 1988-01-22 1989-09-15 UNDECYLESTES OF N-CHLOROPHENOXYOSOIC ACID AND ON THIS ESTER BASED PHARMACEUTICAL PREPARATION FOR TREATMENT OF HYPERLIPIDEMIA

Country Status (6)

Country Link
JP (1) JPH02502998A (en)
DE (1) DE3891219T1 (en)
FR (1) FR2630736B1 (en)
GB (1) GB2221681A (en)
SE (1) SE8903047L (en)
WO (1) WO1989006643A1 (en)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717669A (en) * 1968-06-18 1973-02-20 American Home Prod 2-phenoxyalkanoic acid esters
FR2085634A1 (en) * 1970-04-14 1971-12-31 Synthelabo 2-(parachlorophenoxy)-2-methyl propionic esters - hypolipemics and hypocholesterolemics
GB1422679A (en) * 1972-11-16 1976-01-28 Funai Pharmaceutical Ind Ltd Substituted phenoxy-a-methylpropionic acid derivatives and a process for producing the same
NL7416412A (en) * 1973-12-27 1975-07-01 Siegfried Ag PROCESS FOR PREPARING NEW CHOLESTEROL-GENERAL COMPOUNDS.
JPS5154918A (en) * 1974-10-08 1976-05-14 Nippon Kayaku Kk Jozaino seizoho
NL184308C (en) * 1975-07-24 1989-06-16 Takeda Chemical Industries Ltd PROCESS FOR PREPARING L-ASCORBIC ACID GRANULES.
US4326882A (en) * 1978-08-28 1982-04-27 Ppg Industries, Inc. Trichlorophenoxy alkanoic acid free of chlorinated dibenzo-p-dioxins
JPS5559140A (en) * 1978-10-30 1980-05-02 Sankyo Co Ltd 3,5-dihydroxypentanoic alkyl ester derivative, its preparation and remedy for hyperlipemia containing the same as the effective component
JPS5576840A (en) * 1978-12-01 1980-06-10 Kaken Pharmaceut Co Ltd New oxyacetic acid derivative, its preparation and blood- lipid depressor containing it as active principle
SE450381B (en) * 1979-02-08 1987-06-22 Merz & Co ESTIMATES OF NICOTIC ACID AND 2- (P-CHLORPHENOXY) -ISOSMORIC ACID FOR USE AS A LIPID SENSITIVE AGENT
EP0032631A3 (en) * 1980-01-16 1981-11-11 Fbc Limited Herbicidal phenoxyalkanoic acid derivatives, their preparation, compositions containing them, and their use
AT378952B (en) * 1981-12-14 1985-10-25 Arcana Chem Pharm METHOD FOR PRODUCING PHENOXYISOBUTTERS | UREESTERS
GB2142822B (en) * 1983-06-29 1987-02-11 Alec Stanley Walter Shaw Nicotine lozenges
GB8330407D0 (en) * 1983-11-15 1983-12-21 Sterwin Ag Halocyclopropyl-substituted phenoxyalkanoic acids and esters
FR2598146B1 (en) * 1986-04-30 1989-01-20 Rech Ind NEW PROCESS FOR THE PREPARATION OF FIBRATES.

Also Published As

Publication number Publication date
GB8920466D0 (en) 1989-11-01
FR2630736A1 (en) 1989-11-03
GB2221681A (en) 1990-02-14
FR2630736B1 (en) 1990-08-24
JPH02502998A (en) 1990-09-20
WO1989006643A1 (en) 1989-07-27
SE8903047L (en) 1989-09-15
DE3891219T1 (en) 1990-02-01

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