FR2630736B1 - ESTER UNDECYLIC OF P-CHLOROPHENOXYISOBUTYRIC ACID AND MEDICINE CONTAINING IT FOR THE TREATMENT OF HYPERLIPIDEMIA - Google Patents

ESTER UNDECYLIC OF P-CHLOROPHENOXYISOBUTYRIC ACID AND MEDICINE CONTAINING IT FOR THE TREATMENT OF HYPERLIPIDEMIA

Info

Publication number
FR2630736B1
FR2630736B1 FR888805868A FR8805868A FR2630736B1 FR 2630736 B1 FR2630736 B1 FR 2630736B1 FR 888805868 A FR888805868 A FR 888805868A FR 8805868 A FR8805868 A FR 8805868A FR 2630736 B1 FR2630736 B1 FR 2630736B1
Authority
FR
France
Prior art keywords
undecylic
hyperlipidemia
ester
treatment
medicine containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR888805868A
Other languages
French (fr)
Other versions
FR2630736A1 (en
Inventor
Lev Natanovich Volovelsky
Valery Vladimirovich Natarov
Ivan Sergeevich Chekman
Viktor Andreevich Tumanov
Vitaly Ignatievich Zapadnjuk
Nadezhda Vasilievna Popova
Vera Nikolaevna Shneur
Sergei Alexandrovich Korotkov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH I ENDOKRINOLOG
KI MEDOTSINSKY I IME
Original Assignee
KH I ENDOKRINOLOG
KI MEDOTSINSKY I IME
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KH I ENDOKRINOLOG, KI MEDOTSINSKY I IME filed Critical KH I ENDOKRINOLOG
Publication of FR2630736A1 publication Critical patent/FR2630736A1/en
Application granted granted Critical
Publication of FR2630736B1 publication Critical patent/FR2630736B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers
    • C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C07C69/736—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR888805868A 1988-01-22 1988-05-02 ESTER UNDECYLIC OF P-CHLOROPHENOXYISOBUTYRIC ACID AND MEDICINE CONTAINING IT FOR THE TREATMENT OF HYPERLIPIDEMIA Expired - Fee Related FR2630736B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SU1988/000019 WO1989006643A1 (en) 1988-01-22 1988-01-22 UNDECYLIC ETHER n-CHLOROPHENOXYISOBUTYRIC ACID AND A PHARMACEUTICAL PREPARATION FOR TREATING HYPERLIPEMIA BASED ON IT

Publications (2)

Publication Number Publication Date
FR2630736A1 FR2630736A1 (en) 1989-11-03
FR2630736B1 true FR2630736B1 (en) 1990-08-24

Family

ID=21617183

Family Applications (1)

Application Number Title Priority Date Filing Date
FR888805868A Expired - Fee Related FR2630736B1 (en) 1988-01-22 1988-05-02 ESTER UNDECYLIC OF P-CHLOROPHENOXYISOBUTYRIC ACID AND MEDICINE CONTAINING IT FOR THE TREATMENT OF HYPERLIPIDEMIA

Country Status (6)

Country Link
JP (1) JPH02502998A (en)
DE (1) DE3891219T1 (en)
FR (1) FR2630736B1 (en)
GB (1) GB2221681A (en)
SE (1) SE8903047L (en)
WO (1) WO1989006643A1 (en)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717669A (en) * 1968-06-18 1973-02-20 American Home Prod 2-phenoxyalkanoic acid esters
FR2085634A1 (en) * 1970-04-14 1971-12-31 Synthelabo 2-(parachlorophenoxy)-2-methyl propionic esters - hypolipemics and hypocholesterolemics
GB1422679A (en) * 1972-11-16 1976-01-28 Funai Pharmaceutical Ind Ltd Substituted phenoxy-a-methylpropionic acid derivatives and a process for producing the same
NL7416412A (en) * 1973-12-27 1975-07-01 Siegfried Ag PROCESS FOR PREPARING NEW CHOLESTEROL-GENERAL COMPOUNDS.
JPS5154918A (en) * 1974-10-08 1976-05-14 Nippon Kayaku Kk Jozaino seizoho
NL184308C (en) * 1975-07-24 1989-06-16 Takeda Chemical Industries Ltd PROCESS FOR PREPARING L-ASCORBIC ACID GRANULES.
US4326882A (en) * 1978-08-28 1982-04-27 Ppg Industries, Inc. Trichlorophenoxy alkanoic acid free of chlorinated dibenzo-p-dioxins
JPS5559140A (en) * 1978-10-30 1980-05-02 Sankyo Co Ltd 3,5-dihydroxypentanoic alkyl ester derivative, its preparation and remedy for hyperlipemia containing the same as the effective component
JPS5576840A (en) * 1978-12-01 1980-06-10 Kaken Pharmaceut Co Ltd New oxyacetic acid derivative, its preparation and blood- lipid depressor containing it as active principle
SE450381B (en) * 1979-02-08 1987-06-22 Merz & Co ESTIMATES OF NICOTIC ACID AND 2- (P-CHLORPHENOXY) -ISOSMORIC ACID FOR USE AS A LIPID SENSITIVE AGENT
EP0032631A3 (en) * 1980-01-16 1981-11-11 Fbc Limited Herbicidal phenoxyalkanoic acid derivatives, their preparation, compositions containing them, and their use
AT378952B (en) * 1981-12-14 1985-10-25 Arcana Chem Pharm METHOD FOR PRODUCING PHENOXYISOBUTTERS | UREESTERS
GB2142822B (en) * 1983-06-29 1987-02-11 Alec Stanley Walter Shaw Nicotine lozenges
GB8330407D0 (en) * 1983-11-15 1983-12-21 Sterwin Ag Halocyclopropyl-substituted phenoxyalkanoic acids and esters
FR2598146B1 (en) * 1986-04-30 1989-01-20 Rech Ind NEW PROCESS FOR THE PREPARATION OF FIBRATES.

Also Published As

Publication number Publication date
FR2630736A1 (en) 1989-11-03
GB8920466D0 (en) 1989-11-01
WO1989006643A1 (en) 1989-07-27
DE3891219T1 (en) 1990-02-01
SE8903047D0 (en) 1989-09-15
JPH02502998A (en) 1990-09-20
GB2221681A (en) 1990-02-14
SE8903047L (en) 1989-09-15

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Legal Events

Date Code Title Description
ST Notification of lapse